Zobrazeno 1 - 10 of 43 pro vyhledávání: '"Guanglan, Mo"'
1
Akademický článek
Spatial transcriptomics analysis of neoadjuvant cabozantinib and nivolumab in advanced hepatocellular carcinoma identifies independent mechanisms of resistance and recurrence
Autor: Shuming Zhang, Long Yuan, Ludmila Danilova, Guanglan Mo, Qingfeng Zhu, Atul Deshpande, Alexander T. F. Bell, Jennifer Elisseeff, Aleksander S. Popel, Robert A. Anders, Elizabeth M. Jaffee, Mark Yarchoan, Elana J. Fertig, Luciane T. Kagohara
Publikováno v: Genome Medicine, Vol 15, Iss 1, Pp 1-14 (2023)
Abstract Background Novel immunotherapy combination therapies have improved outcomes for patients with hepatocellular carcinoma (HCC), but responses are limited to a subset of patients. Little is known about the inter- and intra-tumor heterogeneity i
Externí odkaz: https://doaj.org/article/098a7d924d184c9b829632f226e3bd36
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2
Akademický článek
Cancer-associated fibroblast heterogeneity is associated with organ-specific metastasis in pancreatic ductal adenocarcinoma
Autor: Xingyi Pan, Jiaojiao Zhou, Qian Xiao, Kenji Fujiwara, Mengwen Zhang, Guanglan Mo, Wei Gong, Lei Zheng
Publikováno v: Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-6 (2021)
Abstract Background Metastasis occurs in the majority of pancreatic ductal adenocarcinoma (PDAC) patients at diagnosis or following resection. Patients with liver metastasis and those with lung metastasis have significantly different prognosis. Here,
Externí odkaz: https://doaj.org/article/f238506938f847eba77d51ab06e86993
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3
Akademický článek
Integrated immunological analysis of a successful conversion of locally advanced hepatocellular carcinoma to resectability with neoadjuvant therapy
Autor: Ihab Kamel, Elizabeth Jaffee, Qingfeng Zhu, Robert Anders, Won Jin Ho, Mark Yarchoan, Matthew Weiss, Elana J Fertig, Gaurav Sharma, Aleksandra Popovic, Jennifer Durham, Genevieve Stein-O'Brien, Guanglan Mo
Publikováno v: Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Hepatocellular carcinoma (HCC) is the fourth leading cause of cancer death worldwide with a minority of patients being diagnosed early enough for curative-intent interventions. We report the first use of preoperative cabozantinib plus nivolumab to su
Externí odkaz: https://doaj.org/article/bf44b57a61c04baba0f2158f01636ee6
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9
Supplementary Figures 1 through 10 from Heterogeneous Stromal Signaling within the Tumor Microenvironment Controls the Metastasis of Pancreatic Cancer
Autor: Lei Zheng, Elizabeth M. Jaffee, Jennifer Van Eyk, Angen Liu, Guanglan Mo, Rajni Sharma, Annie A. Wu, Jennifer Kleponis, Qian Xiao, Pingbo Zhang, Kelly Foley, Agnieszka A. Rucki
Supplemental Figure S1. Inhibition of Src and IGF-1R kinases results in decreased phosphorylation of AnxA2 at Tyrosine 23 on the cell surface of PDAC cells. Supplemental Figure S2. Inhibition of EGFR kinase does not affect phosphorylation of AnxA2 at
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::103bf4285a7289bc1fc9cf7cbe9540ca
https://doi.org/10.1158/0008-5472.22413704.v1
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