Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Guangjun Han"'
Publikováno v:
Pharmaceutics, Vol 13, Iss 2, p 262 (2021)
The salt-dependent polymorphs of glycine crystals formed from bulk solutions have been a longstanding riddle. In this study, in order to shed fresh light, we studied the effects of seven common salts on primary nucleation of the metastable α-glycine
Externí odkaz:
https://doaj.org/article/e685a0358feb46bc89201cad0900b22a
Autor:
Yin Yani, Reginald B. H. Tan, Vernissa Dilys Chia, Pui Shan Chow, Guangjun Han, Sendhil K. Poornachary
Publikováno v:
Crystal Growth & Design. 17:4844-4854
This study investigated the effects of polymeric additives such as hydroxypropyl methyl cellulose (HPMC) and polyvinylpyrrolidone (PVP) on the growth kinetics of naproxen crystal, a model poorly water-soluble active pharmaceutical ingredient. These a
Publikováno v:
Crystal Growth & Design. 16:6499-6505
The effects of typical inorganic salts on solution-mediated polymorphic transformation from metastable α-glycine to stable γ-glycine were investigated, with the measurement of induction times of γ-glycine nucleation being the key objective. Intere
Publikováno v:
Crystal Growth & Design. 16:749-758
Antisolvent precipitation aided by polymeric additives has increasingly been explored as a method to produce micron-sized/submicron particles of active pharmaceutical ingredients with low aqueous solubility—so as to enhance their dissolution rate a
Publikováno v:
CrystEngComm. 18:462-470
Mechanistic exploration of the salt-dependent polymorphic outcome of solution crystallization of an important classical model compound, glycine, was carried out by measuring the growth rates of α-glycine and γ-glycine single seed crystals in the pr
Publikováno v:
Crystal Growth & Design. 15:1082-1088
The growth of two structurally similar polar crystals, γ-glycine and dl-alanine, in their aqueous supersaturated solutions in the presence of typical inorganic salts was studied using in situ microscopic observations. Surprisingly, it was found that
Publikováno v:
Journal of Molecular Structure. 1076:679-686
Crystal structural investigations and Hirshfeld surface analysis of three halogen atoms (4-Cl, 6-Cl and 4-Br) substituted indole-3-acetonitrile (IAN) were reported in this work. The structures of the present three compounds were characterized by Infr
Publikováno v:
Crystal Growth & Design. 14:1406-1411
The effects of common electrolytes (including inorganic acids, bases, and salts) on dl-alanine nucleation in aqueous solutions have been systematically investigated via measurement of nucleation induction times. It is observed that all the electrolyt
Publikováno v:
Crystal Growth & Design. 12:5555-5560
The effects of various anions and cations dissociated from a spectrum of inorganic salts on the growth of dl-alanine polar c-axis have been systematically investigated using in situ microscopic observations on single seed crystals. Surprisingly, it i
Publikováno v:
Crystal Growth & Design. 12:2213-2220
The growth rates of α- and γ-glycine in basic and acidic aqueous glycine solutions were investigated systematically using in situ microscopic observations on single crystal seeds. The most unexpected observation was that inorganic bases (e.g., NaOH