Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Guangjun Bao"'
Autor:
Guangjun Bao, Xinyi Song, Yiping Li, Zeyuan He, Quan Zuo, Ruiyao E, Tingli Yu, Kai Li, Junqiu Xie, Wangsheng Sun, Rui Wang
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-9 (2024)
Abstract Late-stage specific and selective diversifications of peptides and proteins performed at target residues under ambient conditions are recognized to be the most facile route to various and abundant conjugates. Herein, we report an orthogonal
Externí odkaz:
https://doaj.org/article/368bd739b5164b6abd195fee1139373e
Autor:
Quan Zuo, Yiping Li, Xuanliang Lai, Guangjun Bao, Lu Chen, Zeyuan He, Xinyi Song, Ruiyao E, Pengxin Wang, Yuntao Shi, Huixin Luo, Wangsheng Sun, Rui Wang
Publikováno v:
Advanced Science, Vol 11, Iss 21, Pp n/a-n/a (2024)
Abstract Peptide and protein postmodification have gained significant attention due to their extensive impact on biomolecule engineering and drug discovery, of which cysteine‐specific modification strategies are prominent due to their inherent nucl
Externí odkaz:
https://doaj.org/article/d4f74ca4aea840099933e523b5ba2cfd
Autor:
Yuyang Liu, Zeyuan He, Wen Ma, Guangjun Bao, Yiping Li, Changjun Yu, Jingyue Li, Ruiyao E, Zhaoqing Xu, Rui Wang, Wangsheng Sun
Publikováno v:
Organic Letters. 24:9248-9253
We have developed a method of introducing biological oxime ether fragments into peptides by CuI-catalyzed late-stage modification and functionalization of peptides, utilizing their acid moiety and varied 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b37bf7dd4e567325021ecde4b71c7ccb
https://doi.org/10.1021/acs.orglett.2c03813
https://doi.org/10.1021/acs.orglett.2c03813
Autor:
Changjun Yu, Ruiyao E., Xiao‐Wei Zhang, Wen‐Qian Hu, Guangjun Bao, Yiping Li, Yuyang Liu, Zeyuan He, Jingyue Li, Wen Ma, Ling‐Yun Mou, Rui Wang, Wangsheng Sun
Publikováno v:
ChemMedChem. 18
Innovations in synthetic chemistry have a profound impact on the drug discovery process, and will always be a necessary driver of drug development. As a result, it is of significance to develop novel simple and effective synthetic installation of med
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::763b9971e41d5d3ee78e0a0b74c520a8
https://doi.org/10.1002/cmdc.202200651
https://doi.org/10.1002/cmdc.202200651
Autor:
Hui Liu, Chao Zhong, Li Wang, Guangjun Bao, Jingman Ni, Xu Ouyang, Sanhu Gou, Beibei Li, Yun Zhang, Xinyue Chen
Publikováno v:
Br J Pharmacol
Background and purpose Apolipoprotein A-I (apoA-I) mimetic peptides (AAMPs) are short peptides that can mimic the physiological effects of apoA-I, including the suppression of atherosclerosis by reversely transporting peripheral cholesterol to the li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acbc897e56c5bd434968aa57f16aad52
https://doi.org/10.1111/bph.15213
https://doi.org/10.1111/bph.15213
Autor:
Yiping Li, Jingyue Li, Guangjun Bao, Changjun Yu, Yuyang Liu, Zeyuan He, Peng Wang, Wen Ma, Junqiu Xie, Wangsheng Sun, Rui Wang
Publikováno v:
Organic letters. 24(5)
Herein, we explored an unprecedented mild, nonirritating, conveniently available, and recyclable coupling reagent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::135e7ad31975162115a6ccc57b033d1c
https://pubmed.ncbi.nlm.nih.gov/34994572
https://pubmed.ncbi.nlm.nih.gov/34994572
Autor:
Rui Wang, Yuyang Liu, Jing Rao, Zeyuan He, Tian-Tian Zhao, Liang Hong, Guofeng Li, Yiping Li, Changjun Yu, Guangjun Bao, Junqiu Xie, Peng Wang, Wangsheng Sun
Publikováno v:
Angewandte Chemie (International ed. in English). 60(10)
A non-catalytic, mild, and easy-to-handle protecting group switched 1,3-dipolar cycloaddition (1,3-DC) between bi- or mono-N-protected Dha and C,N-cyclic azomethine imines, which afford various quaternary amino acids with diverse scaffolds, is disclo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01c594e19b947f2d6e372e2bbc447036
https://pubmed.ncbi.nlm.nih.gov/33179384
https://pubmed.ncbi.nlm.nih.gov/33179384
Autor:
Yiping Li, Wangsheng Sun, Zeyuan He, Junxian Yang, Liang Hong, Rui Wang, Guangjun Bao, Changjun Yu, Yuyang Liu
Publikováno v:
Organic Letters. 20:7080-7084
A convenient and functional-group-tolerant organocatalytic asymmetric 1,4-addition of azlactones and dehydroalanine is disclosed. The reaction is used for the first synthesis of chiral α,γ-diamino diacid derivatives with nonadjacent stereogenic cen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d0cb2d923e0ec266986f0450fd78a6
https://doi.org/10.1021/acs.orglett.8b03020
https://doi.org/10.1021/acs.orglett.8b03020
Publikováno v:
ACS Catalysis. 8:1810-1816
Switching the chemo- or regioselectivity from identical starting materials under readily tunable reaction conditions represents a great challenge in medicinal and synthetic organic chemistry. Herein, we report the asymmetric dearomatization/oxa-Micha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b809fd17e1880394b1f8c32f4b13d1b6
https://doi.org/10.1021/acscatal.7b03268
https://doi.org/10.1021/acscatal.7b03268
Autor:
Wangsheng Sun, Guangjun Bao, Gongming Zhu, Liang Hong, Yiping Li, Guofeng Li, Rui Wang, Liwu Huang
Publikováno v:
Organic & Biomolecular Chemistry. 16:3655-3661
A highly efficient strategy for the regio- and stereospecific Friedel-Crafts alkylation of indoles with spiro-epoxyoxindoles has been developed in the mixed solvents of HFIP/H2O (1 : 9) without the use of catalysts. This protocol provides an atomical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acde70928a10bb0fb541fcf54e60afe5
https://doi.org/10.1039/c8ob00861b
https://doi.org/10.1039/c8ob00861b