Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Guanghui Yi"'
Autor:
Bodeng Wu, Weilun Pan, Shihua Luo, Xiangrong Luo, Yitao Zhao, Qi Xiu, Mingzhen Zhong, Zhenxun Wang, Tong Liao, Ningcen Li, Chunchen Liu, Chengtao Nie, Guanghui Yi, Shan Lin, MengChen Zou, Bo Li, Lei Zheng
Publikováno v:
Advanced Science, Vol 11, Iss 18, Pp n/a-n/a (2024)
Abstract Regulation of excessive inflammation and impaired cell proliferation is crucial for healing diabetic wounds. Although plant‐to‐mammalian regulation offers effective approaches for chronic wound management, the development of a potent pla
Externí odkaz:
https://doaj.org/article/877dc799a1424f559838cdae48491d01
Publikováno v:
mBio, Vol 13, Iss 6 (2022)
ABSTRACT The interferon (IFN)-inducible 2′,5′-oligoadenylate synthetase (OAS)-RNase L pathway plays a critical role in antiviral immunity. Group A rotaviruses, including the simian SA11 strain, inhibit this pathway through two activities: an E3-l
Externí odkaz:
https://doaj.org/article/4d9dc90e24a146c1948eb37978821ed6
Autor:
Xin Zhang, Wei Yang, Maigeng Zhou, Xianping Wu, You Li, Guanghui Yi, Xiaobo Zhou, Yin Deng, Jing Zeng, Xinyin Xu, Ting Dong, Shuwen Cheng, Ling Niu, Lishi Zhang
Publikováno v:
BMJ Open, Vol 12, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/e9a3b20d052c441d8af335b642425541
Autor:
Baoyu Zhao, Guanghui Yi, Fenglei Du, Yin-Chih Chuang, Robert C. Vaughan, Banumathi Sankaran, C. Cheng Kao, Pingwei Li
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
Zika virus infection can cause human birth defects and Guillain-Barré syndrome. Here the authors present the structures of the full-length nonstructural protein 5 and its RNA-dependent RNA polymerase domain of Zika virus, which are targets for inhib
Externí odkaz:
https://doaj.org/article/5f7cf37477dd4b07ab2f1f59b91eee8b
Publikováno v:
mBio, Vol 7, Iss 5 (2016)
ABSTRACT The world is at the precipice of a postantibiotic era in which medical procedures and minor injuries can result in bacterial infections that are no longer effectively treated by antibiotics. Cathelicidins are peptides produced by animals to
Externí odkaz:
https://doaj.org/article/dcedfdf085814beaaa83ce5dfbefb490
Publikováno v:
PLoS ONE, Vol 8, Iss 10, p e77846 (2013)
The STING (stimulator of interferon genes) protein can bind cyclic dinucleotides to activate the production of type I interferons and inflammatory cytokines. The cyclic dinucleotides can be bacterial second messengers c-di-GMP and c-di-AMP, 3'5'-3'5'
Externí odkaz:
https://doaj.org/article/db6f370cfc1141f9970cb2e98f85c7a8
Autor:
Yvonne Lai, Guanghui Yi, Alice Chen, Kanchan Bhardwaj, Brady J Tragesser, Rodrigo A Valverde, Adam Zlotnick, Suchetana Mukhopadhyay, C T Ranjith-Kumar, C Cheng Kao
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25837 (2011)
Toll-like Receptor 3 (TLR3) detects double-stranded (ds) RNAs to activate innate immune responses. While poly(I:C) is an excellent agonist for TLR3 in several cell lines and in human peripheral blood mononuclear cells, viral dsRNAs tend to be poor ag
Externí odkaz:
https://doaj.org/article/5f68fb6114f049728ebe21c4cd9f312e
Publikováno v:
Clinica Chimica Acta. 531:177-182
Double stranded DNA (dsDNA) is known to act as a damage-associated molecular pattern (DAMP) that stimulates the body's innate immune response. In general, cyclicGMP-AMP(cGAMP)synthase(cGAS), a DNA sensor, detects these disease-causing DNA and activat
Autor:
Yuncheng Qiao, Dongming Guo, Lei Meng, Qingnan Liu, Xiaohui Liu, Chaoke Tang, Guanghui Yi, Zuo Wang, Weidong Yin, Guoping Tian, Zhonghua Yuan
Publikováno v:
Molecular Medicine Reports. 27
Publikováno v:
Exp Biol Med (Maywood)
Cardiovascular and cerebrovascular diseases, such as coronary heart disease and stroke, caused by atherosclerosis have become the “number one killer”, seriously endangering human health in developing and developed countries. Atherosclerosis mainl