Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Guanghui Qian"'
Autor:
Bihe Zeng, Qin Shen, Bo Wang, Xuan Tang, Jiaqi Jiang, Yiming Zheng, Hongbiao Huang, Wenyu Zhuo, Wang Wang, Yang Gao, Xuan Li, Shuhui Wang, Wenjie Li, Guanghui Qian, Jie Qin, Miao Hou, Haitao Lv
Publikováno v:
Nutrition & Metabolism, Vol 21, Iss 1, Pp 1-13 (2024)
Abstract Background Spexin, a 14 amino acid peptide, has been reported to regulate obesity and its associated complications. However, little is known about the underlying molecular mechanism. Therefore, this study aimed to investigate the effects of
Externí odkaz:
https://doaj.org/article/a8dc69cbdb3a463082ba0c6317b2dd42
Emerging evidence of microbial infection in causing systematic immune vasculitis in Kawasaki disease
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Kawasaki disease (KD) is a systematic vasculitis that is often complicated by coronary artery lesions and is a leading cause of acquired heart disease in developed countries. Previous studies have suggested that genetic susceptibility, together with
Externí odkaz:
https://doaj.org/article/2b262e43cb7a46caa538dc902ba74aa9
Autor:
Hongbiao Huang, Jiaqi Jiang, Xiaosong Shi, Jie Qin, Jinfeng Dong, Lei Xu, Chengcheng Huang, Ying Liu, Yiming Zheng, Miao Hou, Qin Shen, Bihe Zeng, Guanghui Qian, Fang Yang, Haitao Lv
Publikováno v:
Annals of Medicine, Vol 54, Iss 1, Pp 442-453 (2022)
Objective We aimed to develop a nomogram to predict risk of resistance to intravenous immunoglobulin (IVIG) in children with Kawasaki disease in eastern China. Methods We retrospectively analysed the data of children with Kawasaki disease who receive
Externí odkaz:
https://doaj.org/article/11ca87d93a9e448eb4d8a3e2caa62c8b
Autor:
Shuhui Wang, Chuxin Ding, Qiyue Zhang, Miao Hou, Ye Chen, Hongbiao Huang, Guanghui Qian, Daoping Yang, Changqing Tang, Yiming Zheng, Li Huang, Lei Xu, Jiaying Zhang, Yang Gao, Wenyu Zhuo, Bihe Zeng, Haitao Lv
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
BackgroundPredicting intravenous immunoglobulin (IVIG)-resistant Kawasaki disease (KD) can aid early treatment and prevent coronary artery lesions. A clinically consistent predictive model was developed for IVIG resistance in KD.MethodsIn this retros
Externí odkaz:
https://doaj.org/article/1f34ae48bc5d4ff7a260a351ef135587
Autor:
Hongbiao Huang, Jinfeng Dong, Jiaqi Jiang, Fang Yang, Yiming Zheng, Shuhui Wang, Nana Wang, Jin Ma, Miao Hou, Yueyue Ding, Lijun Meng, Wenyu Zhuo, Daoping Yang, Weiguo Qian, Qiaobin Chen, Guoping You, Guanghui Qian, Lei Gu, Haitao Lv
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
AimsThe Ca+/NFAT (Nuclear factor of activated T cells) signaling pathway activation is implicated in the pathogenesis of Kawasaki disease (KD); however, we lack detailed information regarding the regulatory network involved in the human coronary endo
Externí odkaz:
https://doaj.org/article/d54b4b14ae1c467d867c78bd5641bfa3
Autor:
Wei Quan, Jingnan An, Gang Li, Guanghui Qian, Meifang Jin, Chenxi Feng, Si Li, Xiaozhong Li, Yunyun Xu, Xiaohan Hu
Publikováno v:
BMC Pediatrics, Vol 21, Iss 1, Pp 1-10 (2021)
Abstract Background Childhood-onset systemic lupus erythematosus (cSLE) is a kind of chronic inflammatory disease characterized by a highly abnormal immune system. This study aimed to detect the serum levels of Th (T helper) cytokines (IL-2, IL-4, IL
Externí odkaz:
https://doaj.org/article/69917231ce3e48d28a51a04c6b2c21a6
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Viral infectious diseases pose a great challenge to human health around the world. Type I interferons (IFN-Is) function as the first line of host defense and thus play critical roles during virus infection by mediating the transcriptional induction o
Externí odkaz:
https://doaj.org/article/f041c91a33974640bfc5283bfa740969
Autor:
Gen Li, Tianquan Yang, Yanling Chen, Jianping Bao, Di Wu, Xiaohan Hu, Chenxi Feng, Lixiao Xu, Mei Li, Gang Li, Meifang Jin, Yunyun Xu, Rui Zhang, Guanghui Qian, Jian Pan
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Glioblastoma multiforme (GBM) is one of the most malignant primary tumors in humans. Despite standard therapeutic strategy with tumor resection combined with radiochemotherapy, the prognosis remains disappointed. Recently, deubiquitinating enzymes (D
Externí odkaz:
https://doaj.org/article/6b96b017cdee4ad38ce02f9a93c0efb6
Autor:
Jin Ma, Huan Gui, Yunjia Tang, Yueyue Ding, Guanghui Qian, Mengjie Yang, Mei Wang, Xiudao Song, Haitao Lv
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Kawasaki disease (KD) causes acute systemic vasculitis and has unknown etiology. Since the acute stage of KD is the most relevant, the aim of the present study was to identify hub genes in acute KD by bioinformatics analysis. We also aimed at constru
Externí odkaz:
https://doaj.org/article/f618b12ebc4c47dcaaab72531737e321
Autor:
Zhiheng Li, Su Lin Lim, Yanfang Tao, Xiaolu Li, Yi Xie, Chun Yang, Zimu Zhang, You Jiang, Xianbing Zhang, Xu Cao, Hairong Wang, Guanghui Qian, Yi Wu, Mei Li, Fang Fang, Ying Liu, Mingcui Fu, Xin Ding, Zhenghong Zhu, Haitao Lv, Jun Lu, Sheng Xiao, Shaoyan Hu, Jian Pan
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Neuroblastoma (NB) is one of the most common solid tumors in childhood. To date, targeting MYCN, a well-established driver gene in high-risk neuroblastoma, is still challenging. In recent years, inhibition of bromodomain and extra terminal (BET) prot
Externí odkaz:
https://doaj.org/article/1552ef23c4cf4bafb0e15c11abdd4462