Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Guanghu Wang"'
Publikováno v:
Fire, Vol 7, Iss 6, p 180 (2024)
The use of existing natural gas pipelines for the transport of hydrogen/natural gas mixtures can achieve large-scale, long-distance and low-cost hydrogen transportation. A jet fire induced by the leakage of high-pressure pure hydrogen and hydrogen-bl
Externí odkaz:
https://doaj.org/article/8ff244e8c21042e7ac66f2b56c1479c5
Autor:
Ahmed Elsherbini, Alexander S. Kirov, Michael B. Dinkins, Guanghu Wang, Haiyan Qin, Zhihui Zhu, Priyanka Tripathi, Simone M. Crivelli, Erhard Bieberich
Publikováno v:
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-19 (2020)
Abstract Amyloid-β (Aβ) associates with extracellular vesicles termed exosomes. It is not clear whether and how exosomes modulate Aβ neurotoxicity in Alzheimer’s disease (AD). We show here that brain tissue and serum from the transgenic mouse mo
Externí odkaz:
https://doaj.org/article/9759f320d29f4d0ba469088d49ff8979
Autor:
Priyanka Tripathi, Zhihui Zhu, Haiyan Qin, Ahmed Elsherbini, Simone M. Crivelli, Emily Roush, Guanghu Wang, Stefka D. Spassieva, Erhard Bieberich
Publikováno v:
Journal of Lipid Research, Vol 62, Iss , Pp 100021- (2021)
Abstract: Microtubules are polymers composed of αβ-tubulin subunits that provide structure to cells and play a crucial role in in the development and function of neuronal processes and cilia, microtubule-driven extensions of the plasma membrane tha
Externí odkaz:
https://doaj.org/article/1869a351c8ab4cc1b4eb3f8d67de99aa
Autor:
Ji-Na Kong, Zhihui Zhu, Yutaka Itokazu, Guanghu Wang, Michael B. Dinkins, Liansheng Zhong, Hsuan-Pei Lin, Ahmed Elsherbini, Silvia Leanhart, Xue Jiang, Haiyan Qin, Wenbo Zhi, Stefka D. Spassieva, Erhard Bieberich
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 3, Pp 488-506 (2018)
We reported that amyloid β peptide (Aβ42) activated neutral SMase 2 (nSMase2), thereby increasing the concentration of the sphingolipid ceramide in astrocytes. Here, we show that Aβ42 induced mitochondrial fragmentation in wild-type astrocytes, bu
Externí odkaz:
https://doaj.org/article/2e953d848a4e4bdf95da608fbf87f121
Autor:
Liansheng Zhong, Ji Na Kong, Michael B. Dinkins, Silvia Leanhart, Zhihui Zhu, Stefka D. Spassieva, Haiyan Qin, Hsuan-Pei Lin, Ahmed Elsherbini, Rebecca Wang, Xue Jiang, Mariana Nikolova-Karakashian, Guanghu Wang, Erhard Bieberich
Publikováno v:
Journal of Lipid Research, Vol 59, Iss 5, Pp 795-804 (2018)
Sphingolipids are key signaling lipids in cancer. Genome-wide studies have identified neutral SMase-2 (nSMase2), an enzyme generating ceramide from SM, as a potential repressor for hepatocellular carcinoma. However, little is known about the sphingol
Externí odkaz:
https://doaj.org/article/5fdac2cab1a34351b8c39e1c023183be
Autor:
Xue Jiang, Zhihui Zhu, Haiyan Qin, Priyanka Tripathi, Liansheng Zhong, Ahmed Elsherbini, Sanjib Karki, Simone M. Crivelli, Wenbo Zhi, Guanghu Wang, Stefanka D. Spassieva, Erhard Bieberich
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 7 (2019)
Ceramide-rich platforms (CRPs) mediate association of proteins with the sphingolipid ceramide and may regulate protein interaction in membrane contact sites to the cytoskeleton, organelles, and infectious pathogens. However, visualization of ceramide
Externí odkaz:
https://doaj.org/article/e785207524be4ff8905dc698f262b049
Publikováno v:
Journal of Lipid Research, Vol 50, Iss 10, Pp 2103-2110 (2009)
The primary cilium is an important sensory organelle, the regulation of which is not fully understood. We found that in polarized Madin-Darby Canine Kidney cells, the sphingolipid ceramide is specifically distributed to a cis-Golgi compartment at the
Externí odkaz:
https://doaj.org/article/afd78567af324628ac5b90ea286c93fd
Autor:
Jeane Silva, Somsankar Dasgupta, Guanghu Wang, Kannan Krishnamurthy, Edmond Ritter, Erhard Bieberich
Publikováno v:
Journal of Lipid Research, Vol 47, Iss 4, Pp 724-733 (2006)
Bone is the most common site to which breast cancer cells metastasize. We found that osteoblast-like MG63 cells and human bone tissue contain the bile acid salt sodium deoxycholate (DC). MG63 cells take up and accumulate DC from the medium, suggestin
Externí odkaz:
https://doaj.org/article/b157258faedf41e090c918be10cf5409
Autor:
Eric Bradley, Somsankar Dasgupta, Xue Jiang, Xiaying Zhao, Gu Zhu, Qian He, Michael Dinkins, Erhard Bieberich, Guanghu Wang
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110119 (2014)
The sphingosine-1-phosphate (S1P) transporter Spns2 regulates myocardial precursor migration in zebrafish and lymphocyte trafficking in mice. However, its function in cancer has not been investigated. We show here that ectopic Spns2 expression induce
Externí odkaz:
https://doaj.org/article/caf2f567ac1f417c9c79ad0795b0605c
Autor:
Guanghu Wang
Publikováno v:
Dose-Response, Vol 11 (2013)
Although the adult human brain has a small number of neural stem cells, they are insufficient to repair the damaged brain to achieve significant functional recovery for neurodegenerative diseases and stroke. Stem cell therapy, by either enhancing end
Externí odkaz:
https://doaj.org/article/51e4a27f90ee4bd0b85ce86b5b998e9d