Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Guanghan, Ou"'
Autor:
Keyue Xu, Miyuki Shimizu, Toma Yamashita, Mako Fujiwara, Shunya Oikawa, Guanghan Ou, Naho Takazakura, Taichi Kusakabe, Keisuke Takahashi, Keisuke Kato, Kento Yoshioka, Keisuke Obara, Yoshio Tanaka
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract We studied the inhibitory actions of docosahexaenoic acid (DHA) on the contractions induced by carbachol (CCh), angiotensin II (Ang II), and bradykinin (BK) in guinea pig (GP) gastric fundus smooth muscle (GFSM), particularly focusing on the
Externí odkaz:
https://doaj.org/article/841d30230a424536a7c329e8b7221e49
Autor:
Guanghan Ou, Akane Komura, Misaki Hojo, Rina Kato, Masahiro Ikeda, Miki Fujisawa, Keyue Xu, Kento Yoshioka, Keisuke Obara, Yoshio Tanaka
Publikováno v:
Journal of Pharmacological Sciences, Vol 153, Iss 3, Pp 119-129 (2023)
We examined whether U46619 (a prostanoid TP receptor agonist) could enhance the contractions of guinea pig urinary bladder smooth muscle (UBSM) in response to acetylcholine (ACh) and an ATP analog (α,β-methylene ATP (αβ-MeATP)) through stimulatio
Externí odkaz:
https://doaj.org/article/399fcfd3f8a14d0ab0732f60693196b4
Autor:
Kento Yoshioka, Keisuke Obara, Shunya Oikawa, Kohei Uemura, Akina Yamaguchi, Kazuki Fujisawa, Hitomi Hanazawa, Miki Fujiwara, Taison Endoh, Taichi Suzuki, Montserrat De Dios Regadera, Daichi Ito, Noboru Saitoh, Yutaka Nakagome, Toma Yamashita, Mayu Kiguchi, Yuka Saito, Yuri Nakao, Hinako Miyaji, Guanghan Ou, Keyue Xu, Yoshio Tanaka
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract This study was performed to elucidate whether eicosapentaenoic acid (EPA) suppresses spasm-prone blood vessel contractions induced by a thromboxane mimetic (U46619) and prostaglandin F2α (PGF2α) and determine whether the primary target of
Externí odkaz:
https://doaj.org/article/10857a2eae444486b3a4c1d213f72d59
Autor:
Keyue Xu, Miyuki Shimizu, Chika Murai, Miki Fujisawa, Daichi Ito, Noboru Saitoh, Yutaka Nakagome, Mio Yamashita, Azusa Murata, Shunya Oikawa, Guanghan Ou, Kento Yoshioka, Keisuke Obara, Yoshio Tanaka
Publikováno v:
Pharmacology Research & Perspectives, Vol 10, Iss 3, Pp n/a-n/a (2022)
Abstract The inhibitory effects of docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), and linoleic acid (LA) on the contractions induced by five prostanoids and U46619 (a TP receptor agonist) were examined in guinea pig gastric fundus smooth mu
Externí odkaz:
https://doaj.org/article/f72ed198a11f44b28d567848e7428224
Autor:
Mirai Kawakita, Keisuke Obara, Fumiko Yamaki, Ayana Kawaguchi, Keyue Xu, Guanghan Ou, Haruna Yamashita, Rikako Inaba, Yoshio Tanaka, Kento Yoshioka, Rika Yamaguchi
Publikováno v:
Biological and Pharmaceutical Bulletin. 44:1129-1139
Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are n-3 polyunsaturated fatty acids (PUFAs), and are abundant in fish oil. These n-3 PUFAs have been reported to improve the lower gastrointestinal (LGI) disorders such as ulcerative colitis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::982131ca8f96d70ee290545ae674f711
https://doi.org/10.1248/bpb.b21-00362
https://doi.org/10.1248/bpb.b21-00362
Autor:
Kento Yoshioka, Keisuke Obara, Shunya Oikawa, Kohei Uemura, Akina Yamaguchi, Kazuki Fujisawa, Hitomi Hanazawa, Miki Fujiwara, Taison Endoh, Taichi Suzuki, Montserrat De Dios Regadera, Daichi Ito, Noboru Saitoh, Yutaka Nakagome, Toma Yamashita, Mayu Kiguchi, Yuka Saito, Yuri Nakao, Hinako Miyaji, Guanghan Ou, Keyue Xu, Yoshio Tanaka
Publikováno v:
Scientific reports. 12(1)
This study was performed to elucidate whether eicosapentaenoic acid (EPA) suppresses spasm-prone blood vessel contractions induced by a thromboxane mimetic (U46619) and prostaglandin F2α (PGF2α) and determine whether the primary target of EPA is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c436f252b5515dd146972b02c3082175
https://pubmed.ncbi.nlm.nih.gov/35896794
https://pubmed.ncbi.nlm.nih.gov/35896794
Autor:
Guanghan, Ou, Miki, Fujisawa, Ayano, Yashiro, Keyue, Xu, Kento, Yoshioka, Keisuke, Obara, Yoshio, Tanaka
Publikováno v:
Life sciences. 287
We examined the potential stimulatory effects of U46619 (a prostanoid TP receptor agonist) and five prostanoids on the contractile activities of urinary bladder smooth muscle (UBSM), focusing on the role of the TP receptor and its associated CaChange
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6b6ec664da4b73965b6b5383a7bd645b
https://pubmed.ncbi.nlm.nih.gov/34767807
https://pubmed.ncbi.nlm.nih.gov/34767807
Autor:
Kento, Yoshioka, Keisuke, Obara, Shunya, Oikawa, Kohei, Uemura, Akina, Yamaguchi, Kazuki, Fujisawa, Hitomi, Hanazawa, Miki, Fujiwara, Taison, Endoh, Taichi, Suzuki, Montserrat, De Dios Regadera, Daichi, Ito, Guanghan, Ou, Keyue, Xu, Yoshio, Tanaka
Publikováno v:
European journal of pharmacology. 908
Docosahexaenoic acid (DHA, an n-3 polyunsaturated fatty acid) inhibits U46619 (a TP receptor agonist)- and prostaglandin F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::42dce07f58ef5a27aa9b93b6bfe84dfd
https://pubmed.ncbi.nlm.nih.gov/34329614
https://pubmed.ncbi.nlm.nih.gov/34329614
Autor:
Kento Yoshioka, Keisuke Obara, Shunya Ikawa, Kohei Uemura, Akina Yamaguch, Kazuki Fujisawa, Hitomi Hanazawa, Guanghan Ou, Keyue Xu, Yoshio Tanaka
Publikováno v:
Proceedings for Annual Meeting of The Japanese Pharmacological Society. 95:2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a12aa2d0f6f6810085d9e5dc2299ecc
https://doi.org/10.1254/jpssuppl.95.0_2-p-145
https://doi.org/10.1254/jpssuppl.95.0_2-p-145
Autor:
Keisuke Obara, Miki Fujisawa, Keyue Xu, Guanghan Ou, Kento Yoshioka, Ayano Yashiro, Yoshio Tanaka
Publikováno v:
Life Sciences. 287:120130
Aims We examined the potential stimulatory effects of U46619 (a prostanoid TP receptor agonist) and five prostanoids on the contractile activities of urinary bladder smooth muscle (UBSM), focusing on the role of the TP receptor and its associated Ca2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d46e86f4533e0843b67845f2ce02ebea
https://doi.org/10.1016/j.lfs.2021.120130
https://doi.org/10.1016/j.lfs.2021.120130