Zobrazeno 1 - 10 of 57 pro vyhledávání: '"Guangguo, Tan"'
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Untargeted metabolomics reveals the combination effects and mechanisms of Huangqi-fuzi herb-pair against doxorubicin-induced cardiotoxicity
Autor: Zhen Xue, Lingxin Zhuo, Bowen Zhang, Lingmeng Zhu, Xinran Xiang, Chunxia Zhang, Wenyuan Liu, Guangguo Tan, Wenting Liao
Publikováno v: Journal of Ethnopharmacology. 305:116109
Qifu decoction (QFD) is a famous traditional Chinese medicine (TCM) composed of Astragali Radix (HuangQi) and Aconiti Lateralis Radix Praeparaia (Fuzi), which can alleviate doxorubicin (DOX)-induced cardiotoxicity (DIC). However, its protective mecha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e61e80aa27a3ddfca52a02b208e32717
https://doi.org/10.1016/j.jep.2022.116109
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4
Akademický článek
Metabolic profiling provides a system understanding of hypothyroidism in rats and its application.
Autor: Si Wu, Guangguo Tan, Xin Dong, Zhenyu Zhu, Wuhong Li, Ziyang Lou, Yifeng Chai
Publikováno v: PLoS ONE, Vol 8, Iss 2, p e55599 (2013)
BACKGROUND: Hypothyroidism is a chronic condition of endocrine disorder and its precise molecular mechanism remains obscure. In spite of certain efficacy of thyroid hormone replacement therapy in treating hypothyroidism, it often results in other sid
Externí odkaz: https://doaj.org/article/718058a31ead485fab5929578d836d96
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5
Chemical profile of Swertia mussotii Franch and its potential targets against liver fibrosis revealed by cross-platform metabolomics
Autor: Ya Zhang, Qian Zhou, Guangguo Tan, Jing Ma, Xin Ding
Publikováno v: Journal of ethnopharmacology. 274
Ethnopharmacological relevance Swertia mussotii Franch (SMF) is a well-known Tibetan medicine for the treatment of liver disease in China. However, the chemical profile and molecular mechanism of SMF against hepatic fibrosis are not yet well explored
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::073b225f8ebb8e8237f008be78778c6e
https://pubmed.ncbi.nlm.nih.gov/33746001
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6
Akademický článek
Metabonomic profiles delineate the effect of traditional Chinese medicine sini decoction on myocardial infarction in rats.
Autor: Guangguo Tan, Wenting Liao, Xin Dong, Genjing Yang, Zhenyu Zhu, Wuhong Li, Yifeng Chai, Ziyang Lou
Publikováno v: PLoS ONE, Vol 7, Iss 4, p e34157 (2012)
BACKGROUND: In spite of great advances in target-oriented Western medicine for treating myocardial infarction (MI), it is still a leading cause of death in a worldwide epidemic. In contrast to Western medicine, Traditional Chinese medicine (TCM) uses
Externí odkaz: https://doaj.org/article/4c6ec630c9434d768502a4722b9bfb21
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7
Cross-platform metabolic profiling deciphering the potential targets of Shenfu injection against acute viral myocarditis in mice
Autor: Qian Zhou, Wenting Liao, Guangguo Tan, Kui Liu, Hong Wu, Ling Li, Xin Dong
Publikováno v: Journal of Pharmaceutical and Biomedical Analysis. 160:1-11
Acute viral myocarditis (AVMC) is typically caused by cardiotropic viral infection. There is a paucity of specific treatment options available with proven efficacy. Chinese patented pharmaceutical product Shenfu injection (SFI) has potent efficacy on
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::233f5f58c130d153a7b41c9c29d7f99e
https://doi.org/10.1016/j.jpba.2018.07.042
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8
Akademický článek
Potential biomarkers in mouse myocardium of doxorubicin-induced cardiomyopathy: a metabonomic method and its application.
Autor: Guangguo Tan, Ziyang Lou, Wenting Liao, Zhenyu Zhu, Xin Dong, Wei Zhang, Wuhong Li, Yifeng Chai
Publikováno v: PLoS ONE, Vol 6, Iss 11, p e27683 (2011)
BACKGROUND: Doxorubicin (DOX) is one of the most potent antitumor agents available; however, its clinical use is limited because of the risk of severe cardiotoxicity. Though numerous studies have ascribed DOX cardiomyopathy to specific cellular pathw
Externí odkaz: https://doaj.org/article/6e72953c1a834dfd979529f3ee2d19dd
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9
HILIC-MS-based metabolomics reveal that Astragalus polysaccharide alleviates doxorubicin-induced cardiomyopathy by regulating sphingolipid and glycerophospholipid homeostasis
Autor: Haibo Wang, Qian Zhou, Xin Ding, Ya Zhang, Guangguo Tan
Publikováno v: Journal of Pharmaceutical and Biomedical Analysis. 203:114177
Doxorubicin (DOX) is widely used against cancer but carries the risk of a progressive cardiomyopathy. Astragalus polysaccharides (ASP) is the main active ingredient of Astragalus membranaceus Bunge. It has been proved to be effective against DOX-indu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77174c4cb3df36a3ec21749e4057457
https://doi.org/10.1016/j.jpba.2021.114177
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