Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Guangfan, Chi"'
Publikováno v:
Guoji laonian yixue zazhi, Vol 45, Iss 02, Pp 247-251 (2024)
Pathology is a bridge between basic medicine and clinical medicine, and pathology diagnosis is regarded as the "gold standard" of disease diagnosis.Therefore, undergraduate clinical medicine education should be "early clinical" .This paper mainly exp
Externí odkaz:
https://doaj.org/article/5be2b6db152f455a8523cd340a4aa610
Autor:
Xi chen, Zhenchuan Wang, Chen Li, Zhao Zhang, Shan Lu, Xuanzhong Wang, Qi Liang, Xiaoxi Zhu, Chengliang Pan, Qingxuan Wang, Zhilin Ji, Yubo Wang, Meihua Piao, Guangfan Chi, Pengfei Ge
Publikováno v:
Redox Biology, Vol 69, Iss , Pp 103030- (2024)
Ferroptosis is a type of programmed cell death resulting from iron overload-dependent lipid peroxidation, and could be promoted by activating transcription factor 3 (ATF3). SIRT1 is an enzyme accounting for removing acetylated lysine residues from ta
Externí odkaz:
https://doaj.org/article/115613e89ac6441d8510c0023297c5f8
Autor:
Jinying Xu, Tong Ji, Guichen Li, Haiying Zhang, Yangyang Zheng, Meiying Li, Jie Ma, Yulin Li, Guangfan Chi
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract Background Brain lactate concentrations are enhanced in response to cerebral ischemia and promote the formation of reactive astrocytes, which are major components of the neuroinflammatory response and functional recovery, following cerebral
Externí odkaz:
https://doaj.org/article/b93ab8228d714a148f735ba3c578232e
Autor:
Shuang Lv, Jinying Xu, Lin Chen, Haitao Wu, Wei Feng, Yangyang Zheng, Pengdong Li, Haiying Zhang, Lihong Zhang, Guangfan Chi, Yulin Li
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-17 (2020)
Abstract Background Human bone marrow-derived mesenchymal stem cells (hBMSCs) have chondrocyte differentiation potential and are considered to be a cell source for cell-transplantation-mediated repair of cartilage defects, including those associated
Externí odkaz:
https://doaj.org/article/06996a04be314a6c89fafe63be8656e7
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-16 (2020)
Abstract Background The development of somatic reprogramming, especially purely chemical reprogramming, has significantly advanced biological research. And chemical-induced extraembryonic endoderm-like (ciXEN) cells have been confirmed to be an indis
Externí odkaz:
https://doaj.org/article/c3c58903cbe44c5fbf00bf58d614c9d4
The Dual Role of Astrocyte-Derived Exosomes and Their Contents in the Process of Alzheimer’s Disease
Publikováno v:
Journal of Alzheimer's Disease. 91:33-42
Millions of patients worldwide are affected by Alzheimer’s disease (AD), and the number of patients with AD is increasing. However, current treatment can only improve symptoms but cannot cure the disease. Astrocytes, glial cells in the central nerv
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Stem cells constantly encounter as well as respond to a variety of signals in their microenvironment. Although the role of biochemical factors has always been emphasized, the significance of biophysical signals has not been studied until recently. Ad
Externí odkaz:
https://doaj.org/article/2d52bbcdee574c7389c58c899860b7e0
Autor:
Zhijun Li, Yifei Yu, Juanjuan Kang, Yangyang Zheng, Jinying Xu, Kan Xu, Kun Hou, Yi Hou, Guangfan Chi
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 14 (2020)
Schwann cell (SC) transplantation is a promising approach for the treatment of spinal cord injury (SCI); however, SC grafts show a low migratory capacity within the astrocytic environment, which inevitably hampers their therapeutic efficacy. The purp
Externí odkaz:
https://doaj.org/article/7f4bbbec20b943cab26cfa70f74f0f31
Autor:
Meiyu Sun, Guangfan Chi, Juanjuan Xu, Ye Tan, Jiayi Xu, Shuang Lv, Ziran Xu, Yuhan Xia, Lisha Li, Yulin Li
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-13 (2018)
Abstract Background Human mesenchymal stem cell (hMSC) differentiation into osteoblasts has important clinical significance in treating bone injury, and the stiffness of the extracellular matrix (ECM) has been shown to be an important regulatory fact
Externí odkaz:
https://doaj.org/article/53211b917522402d986341a7a6103023
Autor:
Pengdong Li, Shuang Lv, Wenyue Jiang, Lihui Si, Baojian Liao, Guifang Zhao, Ziran Xu, Lina Wang, Jia Zhang, Haitao Wu, Qian Peng, Zhaohui Li, Ling Qi, Guangfan Chi, Yulin Li
Publikováno v:
Annals of translational medicine. 10(18)
Osteoarthritis (OA) is one of the most common joint diseases and a major global public health concern. Mesenchymal stem cells (MSCs) have been widely used for the treatment of OA owing to their paracrine secretion of trophic factors, a phenomenon in