Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Guangchi Sun"'
Autor:
Pengzhan Zhao, Yutian Wei, Guangchi Sun, Lei Xu, Tian Wang, Yufei Tian, Honglu Chao, Yiming Tu, Jing Ji
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-24 (2022)
Abstract Background The microglia-mediated inflammatory response is a vital mechanism of secondary damage following traumatic brain injury (TBI), but the underlying mechanism of microglial activation is unclear. Methods Controlled cortical impact (CC
Externí odkaz:
https://doaj.org/article/eb5ac8db9cc14d6bba024db5fda1c262
Autor:
Zong Miao, Wei Tian, Yangfan Ye, Wei Gu, Zhongyuan Bao, Lei Xu, Guangchi Sun, Chong Li, Yiming Tu, Honglu Chao, Sin Man Lam, Ning Liu, Jing Ji
Publikováno v:
Cell Death and Disease, Vol 13, Iss 6, Pp 1-14 (2022)
Abstract Ferroptosis is a newly identified form of regulated cell death (RCD) characterized by the iron-dependent lipid reactive oxygen species (ROS) accumulation, but its mechanism in gliomas remains elusive. Acyl–coenzyme A (CoA) synthetase long-
Externí odkaz:
https://doaj.org/article/d0452af9e4cf41a3b6bf632b55e0c68c
Autor:
Zhongyuan Bao, Yinlong Liu, Binglin Chen, Zong Miao, Yiming Tu, Chong Li, Honglu Chao, Yangfan Ye, Xiupeng Xu, Guangchi Sun, Pengzhan Zhao, Ning Liu, Yan Liu, Xiaoming Wang, Sin Man Lam, Valerian E. Kagan, Hülya Bayır, Jing Ji
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Prokineticin-2 (Prok2) is a secreted protein involved in many physiological processes. Here, the authors show that Prok2 prevents neuronal cell ferroptosis after traumatic brain injury and its administration before cortical injury reduces neuronal de
Externí odkaz:
https://doaj.org/article/014cfde24f7647fc8390c531c4a06ca5
Autor:
Jing Ji, Yun Chen, Yan Qu, Yongping You, Chong Li, Liang Fan, Honglu Chao, Zhongyuan Bao, Guangchi Sun, Pengzhan Zhao, Zhenyao Chen, Yiming Tu
Supplemental Figure S10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdd9a03406df64678cb7a8a5a4b6c7e8
https://doi.org/10.1158/1078-0432.22473816.v1
https://doi.org/10.1158/1078-0432.22473816.v1
Autor:
Jing Ji, Yun Chen, Yan Qu, Yongping You, Chong Li, Liang Fan, Honglu Chao, Zhongyuan Bao, Guangchi Sun, Pengzhan Zhao, Zhenyao Chen, Yiming Tu
Purpose:Glioblastoma (GBM) is one of the most aggressive and lethal cancer types in humans. The standard treatment approach is surgery followed by chemoradiation. However, the molecular mechanisms of innate tumor radioresistance remain poorly underst
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::092b95b5027b6c808d4c670a13015f41
https://doi.org/10.1158/1078-0432.c.6528606.v1
https://doi.org/10.1158/1078-0432.c.6528606.v1
Autor:
Jing Ji, Yun Chen, Yan Qu, Yongping You, Chong Li, Liang Fan, Honglu Chao, Zhongyuan Bao, Guangchi Sun, Pengzhan Zhao, Zhenyao Chen, Yiming Tu
Supplemental information
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f2e1b2fb964d4fc33e01c42f981e1e
https://doi.org/10.1158/1078-0432.22473786.v1
https://doi.org/10.1158/1078-0432.22473786.v1
Autor:
Yiming Tu, Lei Xu, Jia Xu, Zhongyuan Bao, Wei Tian, Yangfan Ye, Guangchi Sun, Zong Miao, Honglu Chao, Yongping You, Ning Liu, Jing Ji
Publikováno v:
Oncogene. 41:2597-2608
Glioblastoma (GBM) is the most aggressive primary brain tumor as one of the deadliest cancers. The TGF-β signaling acts as an oncogenic factor in GBM, and plays vital roles in development of GBM. SMAD7 is a major inhibitor of TGF-β signaling, while
Autor:
Ning Liu, Zong Miao, Wei Tian, Zhongyuan Bao, Guangchi Sun, Lei Xu, Chong Li, Yangfan Ye, Yiming Tu, honglu Chao, Sin Man Lam, Jing Ji
Background: Ferroptosis is a newly identified form of regulated cell death (RCD) characterized by the iron-dependent lipid reactive oxygen species (ROS) accumulation, but its exact mechanism in gliomas remains elusive. Acyl–coenzyme A (CoA) synthet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8b511ee018a62259a17fd71637a36fd
https://doi.org/10.21203/rs.3.rs-1131699/v1
https://doi.org/10.21203/rs.3.rs-1131699/v1
Autor:
Binglin Chen, Jing Ji, Honglu Chao, Chong Li, Zhongyuan Bao, Pengzhan Zhao, Yiming Tu, Xiaoliu Du, Liang Fan, Guangchi Sun
Publikováno v:
Journal of Cellular and Molecular Medicine
Microglial cells are key component of central nervous system (CNS) and mediate the immune response of the brain under physiological or pathological conditions. It tends to activate into a pro‐inflammatory M1 phenotype after traumatic brain injury (
Autor:
Chong Li, Yiming Tu, Liang Fan, Yan Qu, Yongping You, Guangchi Sun, Zhongyuan Bao, Zhenyao Chen, Jing Ji, Pengzhan Zhao, Yun Chen, Honglu Chao
Publikováno v:
Clinical Cancer Research. 26:1749-1762
Purpose: Glioblastoma (GBM) is one of the most aggressive and lethal cancer types in humans. The standard treatment approach is surgery followed by chemoradiation. However, the molecular mechanisms of innate tumor radioresistance remain poorly unders