Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Guangcheng Qin"'
Autor:
Xiaoyan Zhang, Wei Zhang, Yanyun Wang, Yun Zhang, Dunke Zhang, Guangcheng Qin, Jiying Zhou, Lixue Chen
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
BackgroundCentral sensitization is one of the pivotal pathological mechanisms in chronic migraine (CM). Silent information regulator 1 (SIRT1) was shown to be involved in CM, but its specific mechanism is unclear. Reactive oxygen species (ROS) are in
Externí odkaz:
https://doaj.org/article/e384697e07a54700afec1458178f7827
Autor:
Wei Zhang, Xiaoyan Zhang, Ming Lei, Dunke Zhang, Guangcheng Qin, Jiying Zhou, Lichun Ji, Lixue Chen
Publikováno v:
Antioxidants, Vol 13, Iss 6, p 725 (2024)
Chronic migraine is a disabling disorder without effective therapeutic medicine. AMPA receptors have been proven to be essential to pathological pain and headaches, but the related regulatory mechanisms in chronic migraine have not yet been explored.
Externí odkaz:
https://doaj.org/article/08bcd00126a4419b830101624d9dc761
Autor:
Yun Zhang, Yixin Zhang, Yanyun Wang, Xiaoyan Zhang, Guangcheng Qin, Dunke Zhang, Lixue Chen, Jiying Zhou
Publikováno v:
The Journal of Headache and Pain, Vol 24, Iss 1, Pp 1-17 (2023)
Abstract Background Prior clinical studies suggest a shared mechanism between vestibular symptoms and migraine headache. However, the specific neuroanatomical substrate connecting vestibular symptoms with migraine remains to be largely unknown. Thus,
Externí odkaz:
https://doaj.org/article/b6d0e52b41484f6aa5ab5459ca830604
Autor:
Yanyun Wang, Liang Dong, Yun Zhang, Yixin Zhang, Guangcheng Qin, Dunke Zhang, Lixue Chen, Wei He, Jiying Zhou
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
BackgroundExcessive use of headache treatments often leads to the development, progression and exacerbation of primary headache, which is defined as medication overuse headache (MOH). A significant pathophysiological mechanism of MOH is central sensi
Externí odkaz:
https://doaj.org/article/5cac087387bc4884900cfac57c3b6de6
Publikováno v:
The Journal of Headache and Pain, Vol 23, Iss 1, Pp 1-17 (2022)
Abstract Background The pathogenesis of chronic migraine remains unresolved. Recent studies have affirmed the contribution of GLUA1-containing AMPA receptors to chronic migraine. The dopamine D2 receptor, a member of G protein-coupled receptor superf
Externí odkaz:
https://doaj.org/article/054372d473ae4a038f0fb93492d87ea7
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-19 (2022)
Abstract Background Perioperative neurocognitive disorders (PNDs) are considered the most common postoperative complication in geriatric patients. However, its pathogenesis is not fully understood. Surgery-triggered neuroinflammation is a major contr
Externí odkaz:
https://doaj.org/article/abd63b20455f4392a5d0fa8861bac254
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
BackgroundAccording to our previous study, the loss of inhibitory interneuron function contributes to central sensitization in chronic migraine (CM). Synaptic plasticity is a vital basis for the occurrence of central sensitization. However, whether t
Externí odkaz:
https://doaj.org/article/29daba9e4baf466baa1a2ec010a069db
Autor:
Ruimin Tian, Yun Zhang, Qi Pan, Yunfeng Wang, Qianwen Wen, Xiaoping Fan, Guangcheng Qin, Dunke Zhang, Lixue Chen, Yixin Zhang, Jiying Zhou
Publikováno v:
The Journal of Headache and Pain, Vol 23, Iss 1, Pp 1-18 (2022)
Abstract Background Vestibular symptoms are frequently reported in patients with chronic migraine (CM). However, whether vestibular symptoms arise through overlapping neurobiology of migraine remains to be elucidated. The neuropeptide calcitonin gene
Externí odkaz:
https://doaj.org/article/adc79ee0d31943c1a1e539f3c5f7857c
Autor:
Qi Pan, Yunfeng Wang, Ruimin Tian, Qianwen Wen, Guangcheng Qin, Dunke Zhang, Lixue Chen, Yixin Zhang, Jiying Zhou
Publikováno v:
The Journal of Headache and Pain, Vol 23, Iss 1, Pp 1-14 (2022)
Abstract Background Central sensitization is an important pathophysiological mechanism of chronic migraine (CM), and microglia activation in trigeminocervical complex (TCC) contributes to the development of central sensitization. Emerging evidence im
Externí odkaz:
https://doaj.org/article/fb486b5f54d349f69c83b42af8c1ef0c
Autor:
Qianwen Wen, Yunfeng Wang, Qi Pan, Ruimin Tian, Dunke Zhang, Guangcheng Qin, Jiying Zhou, Lixue Chen
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-25 (2021)
Abstract Background Previous studies have confirmed that the microglial activation and subsequent inflammatory responses in the trigeminal nucleus caudalis (TNC) are involved in the central sensitization of chronic migraine (CM). MicroRNA-155-5p has
Externí odkaz:
https://doaj.org/article/e23ab591161644af8d55717515d51f40