Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Guangcheng Jiang"'
Autor:
Pierre Riviere, John J. Dwyer, John Kraus, Claudio D. Schteingart, Guangcheng Jiang, Nicky Ferdyan, Jennifer Hartwig, Yung-Chih Wang, Kazimierz Wiśniewski, Karthik Srinivasan, Steve Qi, Mark Lu, Dorain Thompson, Sudarkodi Alagarsamy, Monica Mares, Regent Laporte, Halina Wiśniewska, Robert Galyean, Alexander P. Posch, Glenn Croston, Javier Sueiras-Diaz, Diane M. Hargrove
Publikováno v:
Journal of Medicinal Chemistry. 59:3129-3139
Glucagon-like peptide-2 receptor agonists have therapeutic potential for the treatment of intestinal diseases. The native hGLP-2, a 33 amino acid gastrointestinal peptide, is not a suitable clinical candidate, due to its very short half-life in human
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d0de85816c7c44911645bd01597a6a
https://doi.org/10.1021/acs.jmedchem.5b01909
https://doi.org/10.1021/acs.jmedchem.5b01909
Publikováno v:
European Journal of Mass Spectrometry. 7:259-266
We report the electrospray mass spectra and tandem mass (MS/MS) spectra of a series of chemically-stable somatostatin (SRIF) and gonadotropin-releasing hormone (GnRH) analogs which incorporate acylated or alkylated/acylated aminoglycine residues (bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b39fcfb5b6e47bf64fc578375f88562e
https://doi.org/10.1255/ejms.436
https://doi.org/10.1255/ejms.436
Autor:
Struthers Rs, Catherine Rivier, A. G. Craig, Jean Rivier, Guangcheng Jiang, Dean A. Kirby, Laura A. Cervini, S. C. Koerber, John B. Porter
Publikováno v:
Journal of Medicinal Chemistry. 43:807-818
In three earlier papers, the structures and biological potencies of numerous mono- and dicyclic antagonists of GnRH were reported. Among these, two families, each containing two to four members were identified that had very high antagonist potencies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57641cb5dd57c8291421aae94e5c665a
https://doi.org/10.1021/jm990116+
https://doi.org/10.1021/jm990116+
Autor:
Arnold T. Hagler, John S. Porter, Anne Z. Corrigan, Jean Rivier, Guangcheng Jiang, S L Lahrichi, Lila M. Gierasch, Steven C. Koerber, Catherine Rivier, Josep Rizo, Wylie Vale
Publikováno v:
Human Reproduction. 11:133-147
To whom correspondence should be addressedWhile the clinical significance of gonadotrophin-releasing hormone (GnRH)agonists is well recognized, the potential use of GnRH antagonists in humansawaits the availability of potent analogues with no untowar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c21bddb113256904b5670739071fdb
https://doi.org/10.1093/humrep/11.suppl_3.133
https://doi.org/10.1093/humrep/11.suppl_3.133
Publikováno v:
Protein & Peptide Letters. 3:219-224
Abstract: Title glycine derivatives FmocNRlCH(NR2Boc)CO2H (I; Fmoc =9-fluorenyl-methyloxycarbonyl; Boc = Me3CO2C; Rl = H, Me; R2 = H, Me), useful as templates for the introduction of desired functionalities into peptides, were prepared by condensatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c240dfb3acc1e1f2f78a4cc17c775105
https://doi.org/10.2174/092986650304220615122758
https://doi.org/10.2174/092986650304220615122758
Autor:
Jean Rivier, Guangcheng Jiang, Carl A. Hoeger, John B. Porter, A. G. Craig, Steven C. Koerber, L. Simon
Publikováno v:
Proceedings of the National Academy of Sciences. 93:2031-2036
Betidamino acids (a contraction of "beta" position and "amide") are N'-monoacylated (optionally, N'-monoacylated and N-mono- or N,N'-dialkylated) aminoglycine derivatives in which each N'acyl/alkyl group may mimic naturally occurring amino acid side
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2322b9104bc1de75e856812f6368af3e
https://doi.org/10.1073/pnas.93.5.2031
https://doi.org/10.1073/pnas.93.5.2031
Autor:
A Corrigan, C Hoeger, A. G. Craig, John B. Porter, Jean Rivier, Guangcheng Jiang, Wylie Vale, Catherine Rivier
Publikováno v:
Journal of Medicinal Chemistry. 38:2649-2662
A series of antagonists of gonadotropin-releasing hormone (GnRH) homologous to azaline B ([Ac-DNal1,DCpa2,DPal3,Aph5(Atz),DAph6+ ++(Atz),ILys8,DAla10]GnRH) was synthesized, characterized, and tested in a rat antiovulatory assay (AOA). Selected analog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c13aac0d1f44aa0a92d97886170f4da
https://doi.org/10.1021/jm00014a017
https://doi.org/10.1021/jm00014a017
Publikováno v:
Experimental Animals. 44:233-239
Several serotypes of Pseudomonas (P.) aeruginosa were isolated from the oral cavities of researchers, but no positive cases were found among the animals they had contacted or in the environment. These results indicated that researchers are not a sour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d848f4fb65051bcc665ac6d3781f6bd
https://doi.org/10.1538/expanim.44.233
https://doi.org/10.1538/expanim.44.233
Autor:
Steven C. Koerber, Catherine Rivier, A. Grey Craig, Laura A. Cervini, John S. Porter, R. Scott Struthers, Dean A. Kirby, Jean Rivier, Guangcheng Jiang
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::708b62fdba2528cd30f220b834cac21a
https://doi.org/10.1002/chin.200022173
https://doi.org/10.1002/chin.200022173
Autor:
R. Scott Struthers, S L Lahrichi, Laura A. Cervini, Steven C. Koerber, Catherine Rivier, Jean Rivier, Dean A. Kirby, Guangcheng Jiang, Michel Ibea, John S. Porter
Publikováno v:
ChemInform. 31
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a295a5f80a82d18fc783b20a24f99bed
https://doi.org/10.1002/chin.200022171
https://doi.org/10.1002/chin.200022171