Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Guangbiao ZHOU"'
Autor:
Yenan Fu, Xi Zhang, Xiao Liu, Peng Wang, Wenhui Chu, Wei Zhao, Yunling Wang, Guangbiao Zhou, Yu Yu, Hongquan Zhang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract PH20 is a member of the human hyaluronidase family that degrades hyaluronan in the extracellular matrix and controls tumor progression. Inhibition of DNA methyltransferases (DNMTs) leads to elevated hyaluronan levels; however, whether DNMT i
Externí odkaz:
https://doaj.org/article/23e0c21d411e441cb993a30d48244792
Publikováno v:
Chinese Journal of Lung Cancer, Vol 24, Iss 6, Pp 394-403 (2021)
Background and objective Immune checkpoint inhibitors (ICIs) such as antibodies against programmed cell death 1 (PD-1) and programmed cell death ligand 1 (PD-L1), have shown remarkable efficacies in many subtypes of cancers. However, ICIs may also ca
Externí odkaz:
https://doaj.org/article/9cc3cca518f446ec8e34c1d90acbfb4c
Autor:
Xinchun Zhao, Yongchun Zhou, Qian Hu, Sanhui Gao, Jie Liu, Hong Yu, Yanfei Zhang, Guizhen Wang, Yunchao Huang, Guangbiao Zhou
Publikováno v:
Cancer Biology & Medicine, Vol 17, Iss 1, Pp 76-87 (2020)
Objective: Oncogenes have been shown to be drivers of non-small cell lung cancer (NSCLC), yet the tumor suppressing genes involved in lung carcinogenesis remain to be systematically investigated. This study aimed to identify tumor suppressing ubiquit
Externí odkaz:
https://doaj.org/article/c3a6d085bd14496bb0bacd9f7fb6e112
Autor:
Guangbiao Zhou
Publikováno v:
Cancer Biology & Medicine, Vol 16, Iss 4, Pp 700-713 (2019)
Each year there will be an estimated 2.1 million new lung cancer cases and 1.8 million lung cancer deaths worldwide. Tobacco smoke is the No.1 risk factors of lung cancer, accounting for > 85% lung cancer deaths. Air pollution, or haze, comprises amb
Externí odkaz:
https://doaj.org/article/3bc8277838e546a29b9f14c554d8ae8c
Autor:
Lei Gao, Yong Hu, Yahui Tian, Zhenzhen Fan, Kun Wang, Hongdan Li, Qian Zhou, Guandi Zeng, Xin Hu, Lei Yu, Shiyu Zhou, Xinyuan Tong, Hsinyi Huang, Haiquan Chen, Qingsong Liu, Wanting Liu, Gong Zhang, Musheng Zeng, Guangbiao Zhou, Qingyu He, Hongbin Ji, Liang Chen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
The tumor suppressor GATA4 is frequently epigenetically silenced in lung cancer. In this study, Gao et al. demonstrate that GATA4 regulates the expression of TGFBR2 and that TGFRB1 inhibitors can synergise with chemotherapeutics to inhibit the growth
Externí odkaz:
https://doaj.org/article/a22e2b802e16470085f09c63c8826bf0
Autor:
Xiangdong Liu, Bo Liu, Ruihua Li, Fei Wang, Ning Wang, Maihe Zhang, Yang Bai, Jin Wu, Liping Liu, Dongyu Han, Zhiguang Li, Bin Feng, Guangbiao Zhou, Shujing Wang, Li Zeng, Jian Miao, Yiqun Yao, Bin Liang, Lin Huang, Qi Wang, Yingjie Wu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Non-small cell lung cancer (NSCLC) is the most deadly cancer in the world due to its often delayed diagnosis. Identification of biomarkers with high sensitivity, specificity, and accessibility for early detection, such as circulating microRNAs, is th
Externí odkaz:
https://doaj.org/article/4dbe469c23744579b8cc48d3c4704af6
Publikováno v:
Marine Drugs, Vol 19, Iss 9, p 488 (2021)
Worldwide, 19.3 million new cancer cases and almost 10.0 million cancer deaths occur each year. Recently, much attention has been paid to the ocean, the largest biosphere of the earth that harbors a great many different organisms and natural products
Externí odkaz:
https://doaj.org/article/1db06daae08a46d89467184b79302c34
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88886 (2014)
Conventional Sanger sequencing remains time-consuming and laborious. In this study, we developed a rapid improved sequencing protocol of 16S rRNA for pathogens identification by using a new combination of SYBR Green I real-time PCR and Sanger sequenc
Externí odkaz:
https://doaj.org/article/79ce892aaa954833b394b7bec99b1475
Autor:
Qun ZHAO, Mengyuan FENG, Shu JIN, Xiaobo LIU, Shengbao LI, Jian GUO, Xinran CHENG, Guangbiao ZHOU, Xianjun YU
Publikováno v:
Chinese Journal of Natural Medicines. 21:163-171
Autor:
Yenan Fu, Xi Zhang, Xiao Liu, Peng Wang, Wenhui Chu, Wei Zhao, Yunling Wang, Guangbiao Zhou, Yu Yu, Hongquan Zhang
Publikováno v:
Signal transduction and targeted therapy. 7(1)
PH20 is a member of the human hyaluronidase family that degrades hyaluronan in the extracellular matrix and controls tumor progression. Inhibition of DNA methyltransferases (DNMTs) leads to elevated hyaluronan levels; however, whether DNMT inhibitors