Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Guang-dan Zhu"'
Autor:
Hua Fang, Xiequn Xu, Kulvinder Kaur, Matthew Dedek, Guang-dan Zhu, Bae J. Riley, Frank G. Espin, Andria L. Del Tredici, Tanya A. Moreno
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Purpose:HLA-B∗15:02 is strongly associated with life-threatening severe skin hypersensitivity reactions in patients treated with carbamazepine (CBZ) and structurally related medications. FDA-approved labeling recommends HLA-B∗15:02 screening befo
Externí odkaz:
https://doaj.org/article/63105fec94a04c3db4e6542ead2950d1
Autor:
Andria L. Del Tredici, Alka Malhotra, Matthew Dedek, Frank Espin, Dan Roach, Guang-dan Zhu, Joseph Voland, Tanya A. Moreno
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
The CYP2D6 gene encodes an enzyme important in the metabolism of many commonly used medications. Variation in CYP2D6 is associated with inter-individual differences in medication response, and genetic testing is used to optimize medication therapy. T
Externí odkaz:
https://doaj.org/article/f9f5843a4af04f8092783aec5fa9bbe7
Autor:
Guang-Dan, Zhu, Penn, Whitley, Leah, LaRue, Brandon, Adkins, Eric, Dawson, Angela, Huskey, Edmund V, Capparelli, Andria L, Del Tredici
Publikováno v:
The pharmacogenomics journal. 22(1)
Urine drug testing (UDT) is a tool for monitoring drug use, including oxycodone. While variation in cytochrome P450 (CYP) genes is known to alter oxycodone metabolism, its impact on UDT results of oxycodone and its metabolites has not been well-studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85cb1b5c437451451f57c96e7162ec2c
https://pubmed.ncbi.nlm.nih.gov/34480108
https://pubmed.ncbi.nlm.nih.gov/34480108
Publikováno v:
Pharmacogenomics and Personalized Medicine
Background Genetic variants in the BCHE (butyrylcholinesterase) gene are associated with reduced BChE enzyme activity and prolonged post-succinylcholine neuromuscular blockade, which can lead to postanesthetic apnea and respiratory depression. Testin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7cc710fb5aca46d2f7ca7f6dccc42dbd
https://pubmed.ncbi.nlm.nih.gov/33061533
https://pubmed.ncbi.nlm.nih.gov/33061533
Autor:
Hua, Fang, Xiequn, Xu, Kulvinder, Kaur, Matthew, Dedek, Guang-Dan, Zhu, Bae J, Riley, Frank G, Espin, Andria L, Del Tredici, Tanya A, Moreno
Publikováno v:
Frontiers in Pharmacology
Purpose: HLA-B∗15:02 is strongly associated with life-threatening severe skin hypersensitivity reactions in patients treated with carbamazepine (CBZ) and structurally related medications. FDA-approved labeling recommends HLA-B∗15:02 screening bef
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::82b3d865a47e402b71ecf6f6f9989b77
https://pubmed.ncbi.nlm.nih.gov/30971914
https://pubmed.ncbi.nlm.nih.gov/30971914
Autor:
Dan Roach, Joseph R. Voland, Frank G. Espin, Alka Malhotra, Guang dan Zhu, Andria L. Del Tredici, Tanya Moreno, Matthew Dedek
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 9 (2018)
Frontiers in Pharmacology, Vol 9 (2018)
The CYP2D6 gene encodes an enzyme important in the metabolism of many commonly used medications. Variation in CYP2D6 is associated with inter-individual differences in medication response, and genetic testing is used to optimize medication therapy. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704b12c2210dc02d6bd7e85c23f79f30
http://europepmc.org/articles/PMC5895772
http://europepmc.org/articles/PMC5895772
Autor:
Elizabeth J. Gleason, Paul D. Hartley, Robby M. Weimer, Tim L. Kroft, Steven W. L'Hernault, Suzanne Cordovado, Guang-dan Zhu, Melissa Henderson, Paul W. Price, Katherine L. Hill-Harfe
Publikováno v:
Genetics. 191:477-491
Secretory vesicles are used during spermatogenesis to deliver proteins to the cell surface. In Caenorhabditis elegans, secretory membranous organelles (MO) fuse with the plasma membrane to transform spermatids into fertilization-competent spermatozoa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f920f8c5c505734ec669ee52953a80c8
https://doi.org/10.1534/genetics.112.139618
https://doi.org/10.1534/genetics.112.139618
Autor:
Gloria Salazar, Steven W. L'Hernault, Michele M. Doucette, Craig J. Heilman, Allan I. Levey, Stephanie A. Zlatic, Victor Faundez, Babar Fiza, Guang-dan Zhu
Publikováno v:
Molecular Biology of the Cell. 20:1223-1240
Yeast and animal homotypic fusion and vacuole protein sorting (HOPS) complexes contain conserved subunits, but HOPS-mediated traffic in animals might require additional proteins. Here, we demonstrate that SPE-39 homologues, which are found only in an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b9995b98e8916c27e50cef2c257f61
https://doi.org/10.1091/mbc.e08-07-0728
https://doi.org/10.1091/mbc.e08-07-0728
Autor:
Guang-dan Zhu, Steven W. L'Hernault
Publikováno v:
Genetics. 165:145-157
Caenorhabditis elegans spermatid formation involves asymmetric partitioning of cytoplasm during the second meiotic division. This process is mediated by specialized ER/Golgi-derived fibrous body-membranous organelles (FB-MOs), which have a fibrous bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974551ca00b0d99d2e61bdb8572baaa4
https://doi.org/10.1093/genetics/165.1.145
https://doi.org/10.1093/genetics/165.1.145
Autor:
Tim L. Kroft, Katherine L. Hill, Guang-dan Zhu, Elizabeth J. Gleason, Miriam Ratliff, Steven W. L'Hernault, Paul D. Hartley
Publikováno v:
Biology of Reproduction. 77:65-65
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd58ab686c3042e6a44b7c21d2a7817c
https://doi.org/10.1093/biolreprod/77.s1.65b
https://doi.org/10.1093/biolreprod/77.s1.65b