Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Guang-ang Tian"'
Publikováno v:
Brazilian Journal of Medical and Biological Research, Vol 57 (2024)
NLRP1, the first identified inflammasome-forming sensor, is thought to be involved in cancer, yet its definite function in lung adenocarcinoma (LUAD) remains unclear. Herein, we explored the expression and function of NLRP1 in LUAD. Decreased NLRP1 e
Externí odkaz:
https://doaj.org/article/de20bae3a2074743aee6bcbb13412ccf
Autor:
Li-Peng Hu, Kai-Xia Zhou, Yan-Miao Huo, De-Jun Liu, Qing Li, Min-Wei Yang, Pei-Qi Huang, Chun-Jie Xu, Guang-Ang Tian, Lin-Li Yao, Xue-Li Zhang, Ya-Hui Wang, Jun Li, Zhi-Gang Zhang, Shu-Heng Jiang, Xin Xing, Xu Wang, Wei-Ting Qin, Qin Yang
Publikováno v:
Oncogenesis, Vol 10, Iss 3, Pp 1-11 (2021)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers, which lacks effective treatment strategies. There is an urgent need for the development of new strategies for PDAC therapy. The genetic and phenotypic heterogeneity of
Externí odkaz:
https://doaj.org/article/b390422c94f543ee8980cc467d58e1b0
Autor:
Xu Wang, Li-Peng Hu, Wei-Ting Qin, Qin Yang, De-Yu Chen, Qing Li, Kai-Xia Zhou, Pei-Qi Huang, Chun-Jie Xu, Jun Li, Lin-Li Yao, Ya-Hui Wang, Guang-Ang Tian, Jian-Yu Yang, Min-Wei Yang, De-Jun Liu, Yong-Wei Sun, Shu-Heng Jiang, Xue-Li Zhang, Zhi-Gang Zhang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive metastatic disease characterized by an immunosuppressive microenvironment. Here the authors show that a subset of P2RX1-negative neutrophils with immunosuppressive properties accumulate i
Externí odkaz:
https://doaj.org/article/e5c9f48dd02248afa64c33593ecd5868
Autor:
Xiao-Xin Zhang, Bo Ni, Qing Li, Li-Peng Hu, Shu-Heng Jiang, Rong-Kun Li, Guang-Ang Tian, Li-Li Zhu, Jun Li, Xue-Li Zhang, Yan-Li Zhang, Xiao-Mei Yang, Qin Yang, Ya-Hui Wang, Chun-Chao Zhu, Zhi-Gang Zhang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 38, Iss 1, Pp 1-19 (2019)
Abstract Background Gastric cancer is one of the deadliest malignant tumours, with a high incidence in China, and is regulated by aberrantly overexpressed oncogenes. However, existing therapies are insufficient to meet patients’ needs; thus, the id
Externí odkaz:
https://doaj.org/article/9f06d6751bfa474aae58a9424b9acdcd
Autor:
Guang-Ang Tian, Wen-Ting Xu, Yue Sun, Jin Wang, Qing Ke, Meng-Jiao Yuan, Jin-Jin Wang, Chun Zhuang, Qian Gong
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Substantial evidence indicates that brain-derived neurotrophic factor (BDNF) plays an important role in tumorigenesis, in addition to its primary role in neuronal activity. Gastrointestinal stromal tumors (GISTs), which are the most common mesenchyma
Externí odkaz:
https://doaj.org/article/bc9d5e03eea94caf89568f117e3b683f
Autor:
Guang-Ang Tian, Chun-Jie Xu, Kai-Xia Zhou, Zhi-Gang Zhang, Jian-Ren Gu, Xue-Li Zhang, Ya-Hui Wang
Publikováno v:
Journal of Immunology Research, Vol 2020 (2020)
Accumulating evidence has pointed out that metastasis is the leading cause of death in several malignant tumor, including CRC. During CRC, metastatic capacity is closely correlated with reprogrammed energy metabolism. Mitochondrial Pyruvate Carrier 1
Externí odkaz:
https://doaj.org/article/018ed00bbf094826a0892b29d0856e6d
Autor:
Guang-Ang Tian, Wen-Ting Xu, Xue-Li Zhang, Yao-Qi Zhou, Yue Sun, Li-Peng Hu, Shu-Heng Jiang, Hui-Zhen Nie, Zhi-Gang Zhang, Lei Zhu, Jun Li, Xiao-Mei Yang, Lin-Li Yao
Publikováno v:
Matrix Biology. 117:31-45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c51b001ae327e2b5d0096a0679b8338a
https://doi.org/10.1016/j.matbio.2023.02.007
https://doi.org/10.1016/j.matbio.2023.02.007
Autor:
Zhi-Gang Zhang, Qiang Xia, Su-Jae Lee, Ho-Young Lee, Li-Peng Hu, Guang-Ang Tian, Shu-Heng Jiang, Ming-Xuan Feng, Xue-Li Zhang, Hui-Zhen Nie, Lei Zhu, Qin Yang, Ya-Hui Wang, Jun Li, Fang Fang, Xiao-Mei Yang, Qing Li, Yan-Li Zhang
Tumor-associated macrophages (TAM) represent key regulators of the complex interplay between cancer and the immune microenvironment. Matricellular protein SPON2 is essential for recruiting lymphocytes and initiating immune responses. Recent studies h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81cf09cd1af7c903d6c2fc2e038b6569
https://doi.org/10.1158/0008-5472.c.6510335
https://doi.org/10.1158/0008-5472.c.6510335
Autor:
Zhi-Gang Zhang, Yong-Wei Sun, Gary Guishan Xiao, Jun Li, Ya-Hui Wang, Xiao-Mei Yang, Qin Yang, Yan-Li Zhang, Xiao-Yan Cao, Guang-Ang Tian, Yong-Sheng Jiang, Yan-Miao Huo, Ming-Wei Yang, Li-Li Zhu, Qing Li, Ling-Ye Tao, Shu-Heng Jiang, Xiao-Xin Zhang, Li-Peng Hu
Supplymentary data figure 1-8 and table 1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c66c7b189a06e06dbce63f7d1379140
https://doi.org/10.1158/1078-0432.22467476
https://doi.org/10.1158/1078-0432.22467476
Autor:
Zhi-Gang Zhang, Yong-Wei Sun, Gary Guishan Xiao, Jun Li, Ya-Hui Wang, Xiao-Mei Yang, Qin Yang, Yan-Li Zhang, Xiao-Yan Cao, Guang-Ang Tian, Yong-Sheng Jiang, Yan-Miao Huo, Ming-Wei Yang, Li-Li Zhu, Qing Li, Ling-Ye Tao, Shu-Heng Jiang, Xiao-Xin Zhang, Li-Peng Hu
Purpose:Extensive research has reported that the tumor microenvironment components play crucial roles in tumor progression. Thus, blocking the supports of tumor microenvironment is a promising approach to prevent cancer progression. We aimed to deter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac6b6d4d06a592418739bd2f15fca3f5
https://doi.org/10.1158/1078-0432.c.6526655
https://doi.org/10.1158/1078-0432.c.6526655