Výsledky vyhledávání - "Guang-Yun Song"

Modified vaccinia Ankara expressing survivin combined with gemcitabine generates specific antitumor effects in a murine pancreatic carcinoma model

Autor: Guang-Yun Song, Don J. Diamond, Tumul Srivastava, Joshua D. I. Ellenhorn, Sabrina Sun, Hidenobu Ishizaki, Edwin R. Manuel

Publikováno v: Cancer Immunology, Immunotherapy. 60:99-109

Survivin is overexpressed by 70-80% of pancreatic cancers, and is associated with resistance to chemotherapy and a poor prognosis. Gemcitabine has been a standard treatment for patients with advanced pancreatic cancer for a decade. Recent reports hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5741ff5f681bc84c33d56aa5f9072564
https://doi.org/10.1007/s00262-010-0923-0

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Heterologous Prime/Boost Immunization With p53-based Vaccines Combined With Toll-like Receptor Stimulation Enhances Tumor Regression

Autor: Edwin R. Manuel, Hidenobu Ishizaki, Kyla Driscoll Carroll, Tumul Srivastava, Guang-Yun Song, Joshua D. I. Ellenhorn, Don J. Diamond, Vafa Shahabi

Publikováno v: Journal of Immunotherapy. 33:609-617

The p53 gene product is overexpressed in approximately 50% of cancers, making it an ideal target for cancer immunotherapy. We previously demonstrated that a modified vaccinia Ankara (MVA) vaccine expressing human p53 (MVA-p53) was moderately active w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95bb7f45396c45c5d4544955073becab
https://doi.org/10.1097/cji.0b013e3181e032c6

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An MVA vaccine overcomes tolerance to human p53 in mice and humans

Autor: Zhongde Wang, Monica Hollstein, Eric C.C. Huang, Wahajul Haq, Glen R. Gibson, Tumul Srivasta, Pirouz Daftarian, Don J. Diamond, Guang Yun Song, Joshua D. I. Ellenhorn

Publikováno v: Cancer Immunology, Immunotherapy. 56:1193-1205

The cellular regulatory protein p53 is overexpressed by almost 50% of all malignancies making it an attractive target for a vaccine approach to cancer. A number of immunotherapy approaches targeting p53 have been evaluated successfully in murine mode

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6e7f2c23b5f6303e3755d0472b2b07d
https://doi.org/10.1007/s00262-006-0270-3

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Two Distinct Pathways of Immuno-Modulation Improve Potency of p53 Immunization in Rejecting Established Tumors

Autor: Joshua D. I. Ellenhorn, Jeff Longmate, Don J. Diamond, Guang Yun Song, Saima Ali, Pirouz Daftarian, Moshe Faynsod

Publikováno v: Cancer Research. 64:5407-5414

The p53 gene product is overexpressed by almost 50% of cancers, making it an ideal target for cancer immunotherapy. We previously demonstrated rejection of established p53-overexpressing tumors without stimulating autoimmunity by immunization with mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bf6ee6be24bf5c0647190045b92e2c4
https://doi.org/10.1158/0008-5472.can-04-0169

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The heterogeneity in the immune response and efficiency of viral dissemination in brain infected with herpes simplex virus type 1 through peripheral or central route

Autor: William Jia, Guang-Yun Song

Publikováno v: Acta Neuropathologica. 97:649-656

Using immunohistochemistry on adjacent brain sections, we studied the correlation between the dissemination of the virus, the inflammatory responses and the expression of major histocompatibility complex (MHC) proteins in rat brain infected with herp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c062ce846a69f632de4b6c6015ae8a8
https://doi.org/10.1007/s004010051042

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Cell surface expression of MHC molecules in glioma cells infected with herpes simplex virus type-1

Autor: William Jia, Gery DeJong, Guang-Yun Song

Publikováno v: Journal of Neuroimmunology. 93:1-7

9L glioma cells consistently expressed major histocompatibility complex (MHC) class I but not class II molecules. Herpes simplex type-1 virus (HSV-1) infection significantly reduced the expression of MHC I on the cell surface. Recombinant interferons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f938464d38a83bf0346c35ec265a633
https://doi.org/10.1016/s0165-5728(98)00167-2

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Abstract 2420: Modified vaccinia Ankara (MVA) expressing survivin combined with gemcitabine generates specific antitumor effects in a murine pancreatic carcinoma model

Autor: Hidenobu Ishizaki, Joshua D. I. Ellenhorn, Tumul Srivastava, Edwin R. Manuel, Don J. Diamond, Guang-Yun Song

Publikováno v: Cancer Research. 70:2420-2420

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::861e3f33a0a1834b504dcca42da2749e
https://doi.org/10.1158/1538-7445.am10-2420

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Akademický článek

An MVA vaccine overcomes tolerance to human p53 in mice and humans.

Autor: Guang-Yun Song, Gibson, Glen, Wahajul Haq, Huang, Eric C. C., Srivasta, Tumul, Hollstein, Monica, Daftarian, Pirouz, Zhongde Wang, Diamond, Don, Ellenhorn, Joshua D. I.

Publikováno v: Cancer Immunology, Immunotherapy; Aug2007, Vol. 56 Issue 8, p1193-1205, 13p, 5 Graphs

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