Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Guang-Quan Zhao"'
Publikováno v:
The Scientific World Journal, Vol 2, Pp 801-810 (2002)
The formation of germ cells during embryogenesis bears the ultimate importance for the continuation of every species. It becomes evident that mechanisms governing germ cell fate specification are not well conserved across the animal kingdom. In most
Externí odkaz:
https://doaj.org/article/dda7afd2df7a47d58a346f84b26f35e9
Autor:
Miwako Yamamoto, F. Kent Hamra, Robert E. Hammer, Karen M. Chapman, Guang Quan Zhao, Timothy E. Richardson, Bray Denard, Jing Hao
Publikováno v:
Stem Cells. 26:1587-1597
The spermatogenesis and oogenesis-specific transcription factor Sohlh2 is normally expressed only in premeiotic germ cells. In this study, Sohlh2 and several other germ cell transcripts were found to be induced in mouse embryonic stem cells when cult
Publikováno v:
Developmental Biology. 290:81-91
Embryonic stem (ES) cells rely on growth factors provided by feeder cells or exogenously to maintain their pluripotency. In order to identify such factors, we have established sub-lines of STO feeder cells which exhibit variable ability in supporting
Autor:
Kay Carnes, John A. Hassell, Hyunjung Jade Lim, Vadim Grigura, Chen Chen, Marie Claude Hofmann, Theresa L. Murphy, Rex A. Hess, Kenneth M. Murphy, Varadaraj Chandrashekar, Natasza A. Kurpios, Wenjun Ouyang, Silvia Arber, Guang Quan Zhao, Qing Zhou, Alec M. Cheng
Publikováno v:
Nature. 436:1030-1034
Division of spermatogonial stem cells1 produces daughter cells that either maintain their stem cell identity or undergo differentiation to form mature sperm. The Sertoli cell, the only somatic cell within seminiferous tubules, provides the stem cell
Autor:
Guang Quan Zhao, Xiaoxia Qi, Jie Hu, Ya Xiong Chen, Dan Wang, Jing Hao, Yuji Mishina, Teng Guo Li, David L. Garbers
Publikováno v:
Developmental Biology. 276(1):158-171
Bone morphogenetic proteins (BMPs) play essential roles in many aspects of developmental biology. We have previously shown that Bmp7, Bmp8a, and Bmp8b of the 60A class of Bmp genes have additive effects in spermatogenesis and in maintaining the epidi
Autor:
Guang-Quan Zhao
Publikováno v:
genesis. 35:43-56
During the past two decades, a significant amount of data has been accumulated revealing the intriguing functions of bone morphogenetic proteins (BMPs) in all aspects of embryonic development and organogenesis. Numerous genes encoding BMPs, BMP recep
Publikováno v:
Developmental Biology. 240(1):212-222
The specificity of bone morphogenetic proteins (BMPs) to their putative heteromeric receptor complexes in vivo is largely unclear. Closely related BMPs may use the same or different receptor complexes for signaling in a time- and space-dependent mann
Autor:
Ying Ying, Guang-Quan Zhao
Publikováno v:
Developmental Biology. 232:484-492
The primordial germ cells (PGCs) of the mouse are derived from proximal epiblast cells that are adjacent to the extraembryonic ectoderm during gastrulation. Previous studies have demonstrated that extraembryonic ectoderm-derived BMP4 and BMP8B are bo
Autor:
Ying Ying, Guang-Quan Zhao
Publikováno v:
Biology of Reproduction. 63:1781-1786
Decidualization is a process characterized by morphological and functional changes in the uterine stromal cells. In addition to steroid hormones, growth factors are implicated in this process. Using in situ hybridization, we found that mRNAs for seve
Publikováno v:
Molecular Endocrinology. 14:1053-1063
In the mouse embryo, the generation of primordial germ cells (PGCs) from the epiblast requires a bone morphogenetic protein-4 (BMP4) signal from the adjacent extraembryonic ectoderm. In this study, we report that Bmp8b, a member of the Gbb-60A class