Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Guang-Ping Shen"'
Autor:
Girja S. Shukla, Guang-Ping Shen, Christopher J. Murray, Melodie Estabrook, Volker Schellenberger, David N. Krag
Publikováno v:
International Journal of Cancer. 120:2233-2242
A novel β-lactamase scaffold library in which the target-binding moiety is built into the enzyme was generated using phage display technology. The binding element is composed of a fully randomized 8 amino acid loop inserted at position between Y34 a
Autor:
Susan Burdette-Radoux, Susan P. Fuller, Stephanie C. Pero, Christian Thomas, Guang-Ping Shen, Donald L. Weaver, David N. Krag, Girja S. Shukla, Taka Ashikaga
Publikováno v:
Cancer Research. 66:7724-7733
Phage display has been used extensively in vitro and in animal models to generate ligands and to identify cancer-relevant targets. We report here the use of phage-display libraries in cancer patients to identify tumor-targeting ligands. Eight patient
Publikováno v:
Current Genetics. 29:136-142
The A-pathway of development in the basidiomycete fungus Schizophyllum commune may be activated by either of two mating-type loci, A alpha and A beta. A alpha consists of two multiallelic genes, Y and Z. Y contains a putative homeodomain; Z contains
Publikováno v:
Experimental Mycology. 19:16-25
A alpha 1, A alpha 3, and A alpha 4 ds- and ss-DNA probes from the polymorphic A alpha mating-type locus of Schizophyllum commune were used to probe Northern blots of poly(A+) RNA extracted from strains of various A alpha mating types. The purpose of
Publikováno v:
2006 5th IEEE Conference on Sensors.
A novel lumped parameter SPICE model for a thermal flow sensor is presented. The model is constructed by 13 circuit cells consisting of thermal resistors and thermal capacitors. The circuit cell originates from the heat conduction equation using the
Publikováno v:
Radiation research. 161(4)
Most of the DNA damage produced by ionizing radiation is repaired by the base excision repair (BER) pathway. To determine whether the BER genes were up-regulated by low doses of ionizing radiation, we investigated their expression in TK6 human lympho
Publikováno v:
The Journal of biological chemistry. 279(18)
Transcription and repair of many DNA helix-distorting lesions such as cyclobutane pyrimidine dimers have been shown to be coupled in cells across phyla from bacteria to humans. The signal for transcription-coupled repair appears to be a stalled trans
Publikováno v:
DNA repair. 2(6)
There are numerous studies documenting the increase of oxidative DNA damage in the nuclei and mitochondria of senescing cells as well as in tissues of aging animals. Here, we show that in IMR 90 human diploid fibroblasts, DNA repair activity is robus
Autor:
Charles P. Novotny, Zhihua Peng, Guang-Ping Shen, Yabing Chen, Robert C. Ullrich, Dongguang Song
Publikováno v:
Current genetics. 39(5-6)
We have isolated and examined the Aalpha6 mating-type locus of Schizophyllum commune as a first step toward resolving a functional difference between this locus and the Aalpha loci previously studied. Our analyses show Aalpha6 to be remarkably simila
Publikováno v:
Genetics. 147(1)
The Aα locus of the basidiomycete fungus, Schizophyllum commune, regulates sexual development via proteins Y and Z. Each Aα mating type encodes unique Y and Z isoforms. We used two isoforms of Y (Y4 and Y5) and two isoforms of Z (Z4 and Z5) in affi