Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Guang-Di Chen"'
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Hearing impairment is a cardinal feature of Down syndrome (DS), but its clinical manifestations have been attributed to multiple factors. Murine models could provide mechanistic insights on various causes of hearing loss in DS. To investigate mechani
Externí odkaz:
https://doaj.org/article/775fe0127b654807a470ff617fc72d58
Autor:
Senthilvelan Manohar, Guang-Di Chen, Dalian Ding, Lijie Liu, Jian Wang, Yu-Chen Chen, Lin Chen, Richard Salvi
Publikováno v:
Frontiers in Integrative Neuroscience, Vol 16 (2022)
Noise-induced hearing loss (NIHL), caused by direct damage to the cochlea, reduces the flow of auditory information to the central nervous system, depriving higher order structures, such as the hippocampus with vital sensory information needed to car
Externí odkaz:
https://doaj.org/article/11ca1c467da340bfa8f24f88b76d5811
Autor:
Dalian Ding, Haiyan Jiang, Senthilvelan Manohar, Xiaopeng Liu, Li Li, Guang-Di Chen, Richard Salvi
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
2-Hyroxypropyl-beta-cyclodextrin (HPβCD) is being used to treat Niemann-Pick C1, a fatal neurodegenerative disease caused by abnormal cholesterol metabolism. HPβCD slows disease progression, but unfortunately causes severe, rapid onset hearing loss
Externí odkaz:
https://doaj.org/article/5630d4e5b7dc49d89ae5af957b8acc13
Autor:
Guang-Di Chen
Publikováno v:
Journal of Otology, Vol 13, Iss 2, Pp 37-43 (2018)
Pure tone audiometry is a routine clinical examination used to identify hearing loss. A normal pure tone audiogram is usually taken as evidence of normal hearing. Auditory deficits detected in subjects with normal audiograms, such as poor sound discr
Externí odkaz:
https://doaj.org/article/f219e608df9744c4ab5e6dd50c8f6aa9
Autor:
Wen Sun, Yan Sheng, Yu Weng, Chun-Xiao Xu, Susan E.I. Williams, Yu-Tao Liu, Michael A. Hauser, R. Rand Allingham, Ming-Juan Jin, Guang-Di Chen
Publikováno v:
International Journal of Ophthalmology, Vol 7, Iss 3, Pp 550-556 (2014)
AIM: To study the associations between lysyl oxidase-like 1 (LOXL1) polymorphisms and primary open angle glaucoma (POAG) remain inconsistent. In this study, we have performed a meta-analysis to investigate the association of LOXL1 polymorphisms with
Externí odkaz:
https://doaj.org/article/71e71fe3345e4f619863ae662aee7bb4
Autor:
Yu-Chen Chen, Xiaowei Li, Lijie Liu, Jian Wang, Chun-Qiang Lu, Ming Yang, Yun Jiao, Feng-Chao Zang, Kelly Radziwon, Guang-Di Chen, Wei Sun, Vijaya Prakash Krishnan Muthaiah, Richard Salvi, Gao-Jun Teng
Publikováno v:
eLife, Vol 4 (2015)
Hearing loss often triggers an inescapable buzz (tinnitus) and causes everyday sounds to become intolerably loud (hyperacusis), but exactly where and how this occurs in the brain is unknown. To identify the neural substrate for these debilitating dis
Externí odkaz:
https://doaj.org/article/4cb0539c75b24803a50fc6797fc50931
Publikováno v:
Neural Plasticity, Vol 2014 (2014)
Previous studies have shown that sodium salicylate (SS) activates not only central auditory structures, but also nonauditory regions associated with emotion and memory. To identify electrophysiological changes in the nonauditory regions, we recorded
Externí odkaz:
https://doaj.org/article/9408acbe678c47a4aad6d1c1419564f4
Publikováno v:
Hearing research. 426
Hyperacusis is a debilitating loudness intolerance disorder that can evoke annoyance, fear and aural facial pain. Although the auditory system seems to be the "central" player, hyperacusis is linked to more than twenty non-auditory medical disorders
Publikováno v:
Hearing Research. 431:108726
Publikováno v:
Neuromethods ISBN: 9781071620212
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96b1348ebbd0a8fc699899bef2fca668
https://doi.org/10.1007/978-1-0716-2022-9_17
https://doi.org/10.1007/978-1-0716-2022-9_17