Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Guang Y. Li"'
Autor:
Cheng J Ma, Jun P Ren, Guang Y Li, Xiao Y Wu, Dirk G Brockstedt, Peter Lauer, Jonathan P Moorman, Zhi Q Yao
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87821 (2014)
In this study, we engineered Listeria monocytogens (Lm) by deleting the LmΔactA/ΔinlB virulence determinants and inserting HCV-NS5B consensus antigens to develop a therapeutic vaccine against hepatitis C virus (HCV) infection. We tested this recomb
Externí odkaz:
https://doaj.org/article/b77d27cafb5d4771b2591c8646fd8eca
Autor:
Cheng J Ma, Guang Y Li, Yong Q Cheng, Jia M Wang, Ruo S Ying, Lei Shi, Xiao Y Wu, Toshiro Niki, Mitsumi Hirashima, Chuan F Li, Jonathan P Moorman, Zhi Q Yao
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72488 (2013)
Human monocytes/macrophages (M/M(Ф)) of the innate immunity sense and respond to microbial products via specific receptor coupling with stimulatory (such as TLR) and inhibitory (such as Tim-3) receptors. Current models imply that Tim-3 expression on
Externí odkaz:
https://doaj.org/article/c4c46906c0644f28a303916cdbc9c78f
Autor:
Zhi Q. Yao, Zhan S. Jia, Jonathan P. Moorman, Jun P. Ren, Ying Zhang, Guang Y. Li, Yun Zhou, Chang X. Huang, Shun B. Ning, Jian Q. Lian, Ling Wang, Juan Zhao
Publikováno v:
Journal of Leukocyte Biology. 100:1201-1211
T cell dysfunction has a crucial role in establishing and maintaining viral persistence. We have previously shown a decline in miR-181a, which regulates CD4+ T cell responses via DUSP6 overexpression, in individuals with hepatitis C virus (HCV) infec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee946cde1cae30286aeed3112cb6ed74
https://doi.org/10.1189/jlb.5a0316-119rr
https://doi.org/10.1189/jlb.5a0316-119rr
Autor:
Zheng D. Morrison, Shun B. Ning, Juan Zhao, Mohamed El Gazzar, Jun Dai, Jun P. Ren, Zhi Q. Yao, Guang Y. Li, Xiao Y. Wu, Jonathan P. Moorman, Ling Wang, Jeddidiah W. D. Griffin
Publikováno v:
Immunology. 148:377-386
T cells play a pivotal role in controlling viral infection; however, the precise mechanisms responsible for regulating T-cell differentiation and function during infections are incompletely understood. In this study, we demonstrated an expansion of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1170d25f3d99b1bc75570abd2d8b7ac
https://doi.org/10.1111/imm.12616
https://doi.org/10.1111/imm.12616
Autor:
Yong Q. Cheng, Jonathan P. Moorman, Yun Zhou, Zhi Q. Yao, Jia M. Wang, Guang Y. Li, Jun P. Ren, Juan Zhao
Publikováno v:
Immunology. 145:485-497
Host immune responses must be tightly regulated by an intricate balance between positive and negative signals while fighting pathogens; persistent pathogens may usurp these regulatory mechanisms to dampen host immunity to facilitate survival in vivo.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30c01b2e191df932a3589d0803ae07fa
https://doi.org/10.1111/imm.12463
https://doi.org/10.1111/imm.12463
Autor:
Guang Y. Li, Zhi Q. Yao, Jeddidiah W. D. Griffin, Yun Zhou, Chuan F. Li, Zhan S. Jia, Ruo S. Ying, Lei Shi, Jonathan P. Moorman, Jun P. Ren, Yong Q. Cheng
Publikováno v:
Hepatology. 61:1163-1173
T cells play a crucial role in viral clearance or persistence; however, the precise mechanisms that control their responses during viral infection remain incompletely understood. MicroRNA (miR) has been implicated as a key regulator controlling diver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8be60b0b50f119c883a89afd30d67b00
https://doi.org/10.1002/hep.27634
https://doi.org/10.1002/hep.27634
Publikováno v:
Journal of Innate Immunity. 7:116-126
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature suppressor cells that are generated due to aberrant myelopoiesis under pathological conditions. Although MDSCs have been recognized for more than 20 years under the g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eeaaaed35f0939865a1d51ce9a033c4
https://doi.org/10.1159/000368233
https://doi.org/10.1159/000368233
Autor:
Jeddidiah W. D. Griffin, Jia M. Wang, Zhi Q. Yao, Guang Y. Li, Shu M. Lin, Ruo S. Ying, Jun P. Ren, Yong Q. Cheng, Lei Shi, Jonathan P. Moorman, Xiao Y. Wu
Publikováno v:
The Journal of Immunology. 192:649-657
Coinfection of hepatitis B virus (HBV) with hepatitis C virus (HCV) is quite common, leading to an increase in morbidity and mortality. As such, HBV vaccination is recommended in HCV-infected individuals. However, HBV vaccine responses in HCV-infecte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deb42b1af33071925a4442dd479a74f4
https://doi.org/10.4049/jimmunol.1302069
https://doi.org/10.4049/jimmunol.1302069
Autor:
Shigeto Yamada, Toshiro Kawashima, Guang Y. Li, Naoki Kojima, Toshifumi Muraoka, Itaru Watanabe, Yutaka Kunitake, Kazuhiro Sugataka
Publikováno v:
Psychiatry and Clinical Neurosciences. 62:562-567
Aims: A large number of studies on the monoamine systems in Alzheimer's disease (AD) have found abnormalities of the noradrenergic system in the brain, but there has been no report concerning the relationship between noradrenergic activity and cognit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf5bc434a535663dba1408bb0e820095
https://doi.org/10.1111/j.1440-1819.2008.01850.x
https://doi.org/10.1111/j.1440-1819.2008.01850.x
Autor:
Xiao Y. Wu, Jonathan P. Moorman, Zhi Q. Yao, Dirk G. Brockstedt, Cheng J. Ma, Peter Lauer, Jun P. Ren, Guang Y. Li
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 1, p e87821 (2014)
PLoS ONE, Vol 9, Iss 1, p e87821 (2014)
In this study, we engineered Listeria monocytogens (Lm) by deleting the LmΔactA/ΔinlB virulence determinants and inserting HCV-NS5B consensus antigens to develop a therapeutic vaccine against hepatitis C virus (HCV) infection. We tested this recomb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d38360b7186ad8de1a59e19bc0bbb7c6
http://europepmc.org/articles/PMC3909257
http://europepmc.org/articles/PMC3909257