Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Guang Xiu Wang"'
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 20, Iss 12, Pp 1076-1084 (2020)
Objective To study the expression of protein kinase N1 (PKN1) in glioma and its influence on the biological behavior of glioma cells. Methods The expression of PKN1 gene was verified via GEPIA database, and LN229, U87 and A172 gliomas cells were dete
Externí odkaz:
https://doaj.org/article/7033cb6f328e4d06b230b03ead8cf322
Autor:
Fei, Tong, Ji-Xing, Zhao, Zi-Yuan, Fang, Xiao-Teng, Cui, Dong-Yuan, Su, Xing, Liu, Jun-Hu, Zhou, Guang-Xiu, Wang, Zhi-Jun, Qiu, Shi-Zhong, Liu, Jun-Qi, Fu, Chun-Sheng, Kang, Jia-Chong, Wang, Qi-Xue, Wang
Publikováno v:
Pharmacological Research. 187:106606
Epidermal growth factor receptor variant III (EGFRvIII) is a mutant isoform of EGFR with a deletion of exons 2-7 making it insensitive to EGF stimulation and downstream signal constitutive activation. However, the mechanism underlying the stability o
Autor:
Pei-yu Pu, Zhi-fan Jia, Guang-xiu Wang, Xiao Yue, Yan-chao Fu, An-ling Zhang, Lei Han, Chun-zhi Zhang, Qing-yu Zhang, Chun-sheng Kang
Publikováno v:
BMC Cancer, Vol 10, Iss 1, p 367 (2010)
Abstract Background MicroRNAs (miRNAs) can function as either oncogenes or tumor suppressor genes via regulation of cell proliferation and/or apoptosis. MiR-221 and miR-222 were discovered to induce cell growth and cell cycle progression via direct t
Externí odkaz:
https://doaj.org/article/a6c24e6b990643d2a1eb9e62af749527
Autor:
Zhou Hx, Mingzhe Qiu, Zhi-yong Zhang, Peiyu Pu, Jiang H, Guang-xiu Wang, Zhifan Jia, Chunsheng Kang, Jin Chang, Shizhu Yu
Publikováno v:
Cancer Gene Therapy. 13:530-538
Epidermal growth factor receptor (EGFR) had been reported as one of the major responsible genes for malignant progression and phenotype reversion of gliomas, and has been used as one of the most important therapeutic targets. In the present study, sm
Publikováno v:
Chinese Journal of Cancer Research. 14:100-104
Objective: To evaluate the effect of Cx43 gene on gap junction intercellular communication (GJIC) and proliferation of glioma cells. Methods: Cx43 cDNA was transfected into TJ905 human glioblastoma cells using lipofectamine. The expression of Cx43 wa
Publikováno v:
Chinese Journal of Cancer Research. 11:164-168
Objective: To study the effect of antisense EGFR RNA on the growth of human glioma cells in vitro and evaluate the feasibility of targeting EGFR gene for gene therapy of gliomas. Methods: Southern and Northern blot analysis, in situ hybridization and
Autor:
Shizhu Yu, Xuan Zhou, Yue Zhong, Peiyu Pu, Jing Sheng, Peng Xu, Zhifan Jia, Xubo Yuan, Yu Ren, Lei Han, Chunsheng Kang, Guang Xiu Wang
Publikováno v:
Journal of biomaterials science. Polymer edition. 21(3)
MicroRNAs have been demonstrated to be deregulated in different types of cancer. miR-21 is a key player in the majority of cancers. Down-regulation of miR-21 in glioblastoma cells leads to repression of cell growth, increased cellular apoptosis and c
Autor:
Chun-zhi, Zhang, Chun-sheng, Kang, Pei-yu, Pu, Guang-xiu, Wang, Zhi-fan, Jia, An-ling, Zhang, Lei, Han, Peng, Xu
Publikováno v:
Zhonghua zhong liu za zhi [Chinese journal of oncology]. 31(10)
To study the inhibitory effect of knocking down microRNA(miR)-221 and miR-222 on human glioma cell growth and its possible mechanism.miRNA-221/222 antisense oligonucleotides (antisense miR221/222) were transfected into human glioma U251 cells by lipo
Publikováno v:
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. 26(5)
To study the effect of silencing Dicer by small interference RNA (siRNA) to suppress the global microRNA (miRNAs) expression on the biological characteristics of TJ905 glioblastoma cells.The silencing effect of RNA interference on Dicer expression wa
Autor:
Guang-xiu, Wang, Zhi-yong, Zhang, Pei-yu, Pu, Chun-sheng, Kang, Shi-zhu, Yu, Zhi-fan, Jia, Peng, Xu, Xuan, Zhou
Publikováno v:
Zhonghua bing li xue za zhi = Chinese journal of pathology. 38(7)