Zobrazeno 1 - 10
of 336
pro vyhledávání: '"Guang Shu"'
Autor:
Wanhong He, Haijun Zhu, Sufen Zhang, Guang Shu, Han Lei, Maonan Wang, Gang Yin, Xiaohua Ni, Qihan Wu
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
ABSTRACTDrug resistance is the primary contributor to the high mortality rate of ovarian cancer (OC). The loss of BRCA1/2 function is linked to drug sensitivity in OC cells. The aim of this study is to enhance the drug sensitivity of OC cells by indu
Externí odkaz:
https://doaj.org/article/b7ff626e9d9a4df49e95f8f75fa20415
Autor:
Pengyan Lu, Shumin Deng, Jiaxin Liu, Qing Xiao, Zhengwei Zhou, Shuojie Li, Jiaxuan Xin, Guang Shu, Bo Yi, Gang Yin
Publikováno v:
MedComm, Vol 5, Iss 6, Pp n/a-n/a (2024)
Abstract Colorectal cancer (CRC) is one of the leading cancers worldwide, with metastasis being a major cause of high mortality rates among patients. In this study, dysregulated gene Tweety homolog 3 (TTYH3) was identified by Gene Expression Omnibus
Externí odkaz:
https://doaj.org/article/f0aa1de1ca4144098e509b24bc9c04ef
Autor:
Wanhong He, Haijun Zhu, Sufen Zhang, Guang Shu, Han Lei, Gang Yin, Xiaohua Ni, Maonan Wang, Qihan Wu
Publikováno v:
Clinical and Experimental Obstetrics & Gynecology, Vol 51, Iss 5, p 109 (2024)
Background: Ovarian cancer has a poor prognosis, and DNA damage-response (DDR) genes are associated with both its occurrence and prognosis. However, previous studies have mostly focused on genetic mutations, with no clear conclusions on epigenetic fa
Externí odkaz:
https://doaj.org/article/2fe8ade770c9429882de5dfb8f3a9a28
Autor:
Jiaxin Liu, Yimin Li, Qing Xiao, Yuanyuan Li, Yuqian Peng, Yaqi Gan, Guang Shu, Hanxi Yi, Gang Yin
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background The incidence of colorectal cancer (CRC) is considered to be the third-highest malignant tumor among all carcinomas. The alterations in cellular bioenergetics (metabolic reprogramming) are associated with several malignant phenoty
Externí odkaz:
https://doaj.org/article/072de8884c574f9588cfb2ccde61b7da
Autor:
Jiaqi Liu, Guang Shu, Anqi Wu, Xiaojun Zhang, Zhengwei Zhou, Ayesha B. Alvero, Gil Mor, Gang Yin
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Ovarian cancer (OC) is one of the leading gynecologic cancers worldwide. Cancer stem-like cells are correlated with relapse and resistance to chemotherapy. Twist1, which is involved in ovarian cancer stem-like cell differentiation, is positi
Externí odkaz:
https://doaj.org/article/6776039f3d7a469d9fb97b18f73d4388
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-14 (2022)
Abstract Multiple evidence shows that metformin serves as a potential agent for Colorectal Cancer (CRC) treatment, while its molecular mechanisms still require detailed investigation. Here, we revealed that metformin specifically suppressed the proli
Externí odkaz:
https://doaj.org/article/c442c496f6824f8f90d2662db5df06cd
Autor:
Yimin Li, Yaqi Gan, Jiaxin Liu, Juanni Li, Zhengwei Zhou, Ruotong Tian, Ruizheng Sun, Jiaqi Liu, Qing Xiao, Yuanyuan Li, Pengyan Lu, Yulong Peng, Yuqian Peng, Guang Shu, Gang Yin
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract Oxaliplatin is widely used in the frontline treatment of colorectal cancer (CRC), but an estimated 50% of patients will eventually stop responding to treatment due to acquired resistance. This study revealed that diminished MEIS1 expression
Externí odkaz:
https://doaj.org/article/1c11cfd15991407f8e4f20af73aa6c5c
Autor:
Jiaqi Liu, Qing Xiao, Jiani Xiao, Chenxi Niu, Yuanyuan Li, Xiaojun Zhang, Zhengwei Zhou, Guang Shu, Gang Yin
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-23 (2022)
Abstract The Wnt/β-catenin pathway comprises a family of proteins that play critical roles in embryonic development and adult tissue homeostasis. The deregulation of Wnt/β-catenin signalling often leads to various serious diseases, including cancer
Externí odkaz:
https://doaj.org/article/910400280fd140a69090e0dab18737eb
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Natural killer (NK) cells are an important component of the innate immune system due to their strong ability to kill virally infected or transformed cells without prior exposure to the antigen (Ag). However, the biology of human NK (hNK) cells has la
Externí odkaz:
https://doaj.org/article/4d5774e4ac8d45a3be0cccea4b8151ea
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-15 (2019)
Abstract N6-methyladenosine (m6A) is methylation that occurs in the N6-position of adenosine, which is the most prevalent internal modification on eukaryotic mRNA. Accumulating evidence suggests that m6A modulates gene expression, thereby regulating
Externí odkaz:
https://doaj.org/article/9552dd5f313a45ddacdda62c1c50dc63