Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Guang Sheng, Ling"'
Autor:
Ronghui Liang, Zi-Wei Ye, Zhenzhi Qin, Yubin Xie, Xiaomeng Yang, Haoran Sun, Qiaohui Du, Peng Luo, Kaiming Tang, Bodan Hu, Jianli Cao, Xavier Hoi-Leong Wong, Guang-Sheng Ling, Hin Chu, Jiangang Shen, Feifei Yin, Dong-Yan Jin, Jasper Fuk-Woo Chan, Kwok-Yung Yuen, Shuofeng Yuan
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Host survival depends on the elimination of virus and mitigation of tissue damage. Herein, we report the modulation of D-mannose flux rewires the virus-triggered immunometabolic response cascade and reduces tissue damage. Safe and inexpensiv
Externí odkaz:
https://doaj.org/article/172ab913f5fd4fd68985cd7d66bf32cb
Autor:
Chi-Ho Lee, Victor Gray, Jia Ming Nickolas Teo, Anthony Raymond Tam, Carol Ho-Yi Fong, David Tak-Wai Lui, Polly Pang, Kwok Hung Chan, Ivan Fan-Ngai Hung, Kathryn Choon-Beng Tan, Guang Sheng Ling
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Acquiring protective immunity through vaccination is essential, especially for patients with type 2 diabetes who are vulnerable for adverse clinical outcomes during coronavirus disease 2019 (COVID-19) infection. Type 2 diabetes (T2D) is associated wi
Externí odkaz:
https://doaj.org/article/0e4fa53a78da437098c91497385d9875
Autor:
Bao-Zhong Zhang, Huiping Shuai, Hua-Rui Gong, Jing-Chu Hu, Bingpeng Yan, Terrence Tsz-Tai Yuen, Ye-Fan Hu, Chaemin Yoon, Xiao-Lei Wang, Yuxin Hou, Xuansheng Lin, Xiner Huang, Renhao Li, Yee Man Au-Yeung, Wenjun Li, Bingjie Hu, Yue Chai, Ming Yue, Jian-Piao Cai, Guang Sheng Ling, Ivan Fan-Ngai Hung, Kwok-Yung Yuen, Jasper Fuk-Woo Chan, Jian-Dong Huang, Hin Chu
Publikováno v:
JCI Insight, Vol 7, Iss 11 (2022)
SARS-CoV-2 has been confirmed in over 450 million confirmed cases since 2019. Although several vaccines have been certified by the WHO and people are being vaccinated on a global scale, it has been reported that multiple SARS-CoV-2 variants can escap
Externí odkaz:
https://doaj.org/article/c9913ac58afe4a5f88ec82e6ea2668a0
Autor:
Norzawani Buang, Lunnathaya Tapeng, Victor Gray, Alessandro Sardini, Chad Whilding, Liz Lightstone, Thomas D. Cairns, Matthew C. Pickering, Jacques Behmoaras, Guang Sheng Ling, Marina Botto
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Lupus pathogenesis is associated with high type 1 interferon stimulated gene (ISG) expression. Here, the authors correlate ISG expression in CD8+ T cells from lupus nephritis patients with abnormal mitochondrial function, implicating increased NAD co
Externí odkaz:
https://doaj.org/article/956b2c52bede4e939180a254c3701f31
Autor:
Zi-Wei Ye, Chon Phin Ong, Kaiming Tang, Yilan Fan, Cuiting Luo, Runhong Zhou, Peng Luo, Yun Cheng, Victor Sebastien Gray, Pui Wang, Hin Chu, Jasper Fuk-Woo Chan, Kelvin Kai-Wang To, Honglin Chen, Zhiwei Chen, Kwok-Yung Yuen, Guang Sheng Ling, Shuofeng Yuan, Dong-Yan Jin
Publikováno v:
Cellular & Molecular Immunology. 19:588-601
Live attenuated vaccines might elicit mucosal and sterilizing immunity against SARS-CoV-2 that the existing mRNA, adenoviral vector and inactivated vaccines fail to induce. Here, we describe a candidate live attenuated vaccine strain of SARS-CoV-2 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5e4f516a45ead462b233debb5d384a7
https://doi.org/10.1038/s41423-022-00855-4
https://doi.org/10.1038/s41423-022-00855-4
Autor:
Roberta Bulla, Claudio Tripodo, Damiano Rami, Guang Sheng Ling, Chiara Agostinis, Carla Guarnotta, Sonia Zorzet, Paolo Durigutto, Marina Botto, Francesco Tedesco
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-11 (2016)
C1q is known to initiate the activation of the complement classical pathway. Here, the authors show the C1q is expressed in the tumour microenvironment and can promote cancer cell migration and adhesion in a complement activation-independent manner.
Externí odkaz:
https://doaj.org/article/2b1fca59ed134efe8e0682260b30cecc
Autor:
Alessandro Sardini, Marina Botto, Jacques Behmoaras, Chad Whilding, Norzawani Buang, Victor Gray, Lunnathaya Tapeng, Guang Sheng Ling, Matthew C. Pickering, Thomas D. Cairns, Liz Lightstone
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
The majority of patients with systemic lupus erythematosus (SLE) have high expression of type I IFN-stimulated genes. Mitochondrial abnormalities have also been reported, but the contribution of type I IFN exposure to these changes is unknown. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ddd655a2f9ffa791029ab75a1223cad
https://doaj.org/article/956b2c52bede4e939180a254c3701f31
https://doaj.org/article/956b2c52bede4e939180a254c3701f31
Autor:
Weixin, Chen, Jia Ming Nickolas, Teo, Siu Wah, Yau, Melody Yee-Man, Wong, Chun-Nam, Lok, Chi-Ming, Che, Asif, Javed, Yuanhua, Huang, Stephanie, Ma, Guang Sheng, Ling
Publikováno v:
Cell reports. 41(7)
Identifying signals that govern the differentiation of tumor-infiltrating CD8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5d223d9a656a64fb855c583a41bef814
https://pubmed.ncbi.nlm.nih.gov/36384131
https://pubmed.ncbi.nlm.nih.gov/36384131
Autor:
Weixin Chen, Jia Ming Nickolas Teo, Siu Wah Yau, Yee-Man Melody Wong, Chun-Nam Lok, Chi-Ming Che, Asif Javed, Yuanhua Huang, Stephanie Ma, Guang Sheng Ling
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d73d890ddb1791f3484e30cdb4fb165f
https://doi.org/10.2139/ssrn.4055642
https://doi.org/10.2139/ssrn.4055642
Publikováno v:
Journal of Autoimmunity. 132:102861
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by multiple organ inflammatory damage and wide spectrum of autoantibodies. The autoantibodies, especially anti-dsDNA and anti-Sm autoantibodies are highly specific to SLE, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1ddb5d3f344e80693ab85ef6bd9b44a
https://doi.org/10.1016/j.jaut.2022.102861
https://doi.org/10.1016/j.jaut.2022.102861