Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Guang Huan-Tu"'
Autor:
Pamela Zhang, Guang Huan Tu, Jie Wei, Pamela Santiago, Lance R. Larrabee, Sindy Liao-Chan, Tina Mistry, Matthew Ling-Hon Chu, Tao Sai, Kevin Lindquist, Hua Long, Javier Chaparro-Riggers, Shahram Salek-Ardakani, Yik Andy Yeung
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3117-3123.e5 (2019)
Summary: Agonistic antibodies targeting the tumor necrosis factor (TNF) superfamily of co-stimulatory receptors (TNFRSF) are progressing through various stages of clinical development for cancer treatment, but the desired and defining features of the
Externí odkaz:
https://doaj.org/article/44cb539f22be4485ababb5654bc38b0f
Autor:
John C. Lin, Todd VanArsdale, Mengli Xiong, Chi Ying, Hui Wang, Xiaoai Li, Konstantinos Tsaparikos, Guang Huan Tu, Kathryn Logronio, Winston Evering, Mark Elliott, Bart Jessen, Timothy S. Fisher, Li-Fen Lee, Shihao Chen
Supplementary Figure S1. Anti-4-1BB and anti-PD-1 synergized to suppress B16F10 tumor growth. Supplementary Figure S2. The flow cytometric gating strategy to analyze immune cells. Supplementary Figure S3. Elevated expression of genes associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8200d54b7a2a76d4decd0c9ef8219587
https://doi.org/10.1158/2326-6066.22537411.v1
https://doi.org/10.1158/2326-6066.22537411.v1
Autor:
John C. Lin, Todd VanArsdale, Mengli Xiong, Chi Ying, Hui Wang, Xiaoai Li, Konstantinos Tsaparikos, Guang Huan Tu, Kathryn Logronio, Winston Evering, Mark Elliott, Bart Jessen, Timothy S. Fisher, Li-Fen Lee, Shihao Chen
Immunotherapies targeting the programmed death 1 (PD-1) coinhibitory receptor have shown great promise for a subset of patients with cancer. However, robust and safe combination therapies are still needed to bring the benefit of cancer immunotherapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a374458d21a5aed28dfc01f5d484e052
https://doi.org/10.1158/2326-6066.c.6548434.v1
https://doi.org/10.1158/2326-6066.c.6548434.v1
Autor:
John C. Lin, Todd VanArsdale, Mengli Xiong, Chi Ying, Hui Wang, Xiaoai Li, Konstantinos Tsaparikos, Guang Huan Tu, Kathryn Logronio, Winston Evering, Mark Elliott, Bart Jessen, Timothy S. Fisher, Li-Fen Lee, Shihao Chen
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2db9bbc98bbd2a05f3a1308d43491afa
https://doi.org/10.1158/2326-6066.22537414
https://doi.org/10.1158/2326-6066.22537414
Autor:
Shahram Salek-Ardakani, Matthew Ling-Hon Chu, Tina Mistry, Javier Chaparro-Riggers, Pamela Zhang, Yik Andy Yeung, Jie Wei, Tao Sai, Pamela Rojas De Santiago, Kevin Lindquist, Sindy Liao-Chan, Hua Long, Lance R. Larrabee, Guang Huan Tu
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3117-3123.e5 (2019)
Summary: Agonistic antibodies targeting the tumor necrosis factor (TNF) superfamily of co-stimulatory receptors (TNFRSF) are progressing through various stages of clinical development for cancer treatment, but the desired and defining features of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09837041a8fb9346d913b0ce723e67f3
https://doi.org/10.1016/j.celrep.2019.05.027
https://doi.org/10.1016/j.celrep.2019.05.027
Autor:
Guang-Huan Tu, Wenwu Zhai, Li-Fen Lee, Yolanda S. Kap, Nikki van Driel, Jan Bauer, John C. Lin, Bert A. 't Hart, Jon D. Laman, Jordon Dunham, Irene Ni
Publikováno v:
Journal of NeuroImmune Pharmacology, 11(1), 73-83. Springer New York
Journal of neuroimmune pharmacology, 11(1), 73-83. SPRINGER
Journal of neuroimmune pharmacology, 11(1), 73-83. SPRINGER
Non-human primate models of human disease have an important role in the translation of a new scientific finding in lower species into an effective treatment. In this study, we tested a new therapeutic antibody against the IL-7 receptor alpha chain (C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::748cee3b79b00416d7294bf807cdc869
https://pure.eur.nl/en/publications/37786209-5455-440c-b75f-23dec1a41d1e
https://pure.eur.nl/en/publications/37786209-5455-440c-b75f-23dec1a41d1e
Autor:
Colleen Brown, John C. Lin, Li Mei, Timothy Affolter, Jessica Yu, Sherman Michael Chin, Jeanette Dilley, Irene Ni, Wenwu Zhai, Bora Han, Arvind Rajpal, Kathryn Logronio, Guang Huan Tu, Li-Fen Lee, Charles Takeshi Appah
Publikováno v:
Proceedings of the National Academy of Sciences. 109:12674-12679
Genetic variation in the IL-7 receptor-α ( IL-7R ) gene is associated with susceptibility to human type 1 diabetes (T1D). Here we investigate the therapeutic efficacy and mechanism of IL-7Rα antibody in a mouse model of T1D. IL-7Rα antibody induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::118df3cc4d7cde592d22227550353b6a
https://doi.org/10.1073/pnas.1203795109
https://doi.org/10.1073/pnas.1203795109
Autor:
Melissa Gonzalez-Edick, Minh C. Nguyen, Kathryn E. Koprivnikar, Guang Huan Tu, Karin Jooss, Thomas Harding
Publikováno v:
Cancer Immunology, Immunotherapy. 59:1313-1323
A critical factor in clinical development of cancer immunotherapies is the identification of tumor-associated antigens that may be related to immunotherapy potency. In this study, protein microarrays containing >8,000 human proteins were screened wit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c39107d0bea1060d6ca40c728c0fdb0
https://doi.org/10.1007/s00262-010-0858-5
https://doi.org/10.1007/s00262-010-0858-5
Autor:
Thomas Harding, Melinda VanRoey, Andrew Simmons, Karin Jooss, Guang Huan Tu, Jianmin Fang, Saili Yi, Minh Nguyen
Publikováno v:
Molecular Therapy. 15(6):1153-1159
Monoclonal antibody (mAb) delivery by gene transfer in vivo may be an attractive alternative to current mAb therapies for applications that require long-term therapy. This article describes a transfer system that allows inducible high-level expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22b127d8c51bb81b83f4c8e155afdbd1
Autor:
Tim Clackson, Melissa Gonzalez-Edick, Thomas Harding, Karin Jooss, Victor M. Rivera, Minh C. Nguyen, Guang Huan-Tu
Publikováno v:
Molecular Therapy. 15(5):912-920
Regulated gene expression may be required for the clinical development of certain gene therapies. Several approaches have been developed that allow pharmacologic control of transgene expression, including the dimerizer-regulated transcriptional syste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98faab08328390127a9b5f5058a86944