Zobrazeno 1 - 10
of 214
pro vyhledávání: '"Guang⁃ming LU"'
Autor:
Guang-Ming Lu, Huan-Huan Hu, Chia-Chun Chang, Jiale Zhong, Xian Zhou, Chen-Jun Guo, Tianyi Zhang, Yi-Lan Li, Boqi Yin, Ji-Long Liu
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Background PRPP synthase (PRPS) transfers the pyrophosphate groups from ATP to ribose-5-phosphate to produce 5-phosphate ribose-1-pyrophosphate (PRPP), a key intermediate in the biosynthesis of several metabolites including nucleotides, dinu
Externí odkaz:
https://doaj.org/article/7f27df0d7dd448b29cad47f0feae8a41
Autor:
Jing Pan, Long Ma, Yu-Xia Tang, Ying Tian, Yi-Hang Lin, Long-Jiang Zhang, Feng Gao, Guang-Ming Lu
Publikováno v:
Arabian Journal of Chemistry, Vol 15, Iss 7, Pp 103908- (2022)
A series of novel 4-aminoquinazoline derivatives were designed, synthesized and biological properties on nuclear factor-kappaB (NF-κb) pathway inhibitory and potential in vitro anti-proliferation against breast cancer lines were also evaluated. Amon
Externí odkaz:
https://doaj.org/article/ab0ef43936954955b4d70ead8248b50d
Autor:
Huan-Huan Hu, Guang-Ming Lu, Chia-Chun Chang, Yilan Li, Jiale Zhong, Chen-Jun Guo, Xian Zhou, Boqi Yin, Tianyi Zhang, Ji-Long Liu
Publikováno v:
eLife, Vol 11 (2022)
Phosphoribosyl pyrophosphate (PRPP) is a key intermediate in the biosynthesis of purine and pyrimidine nucleotides, histidine, tryptophan, and cofactors NAD and NADP. Abnormal regulation of PRPP synthase (PRPS) is associated with human disorders, inc
Externí odkaz:
https://doaj.org/article/46c77353daa547c5963b470113dda424
Autor:
Jiale Zhong, Chen-Jun Guo, Xian Zhou, Chia-Chun Chang, Boqi Yin, Tianyi Zhang, Huan-Huan Hu, Guang-Ming Lu, Ji-Long Liu
Publikováno v:
eLife, Vol 11 (2022)
The bifunctional enzyme Δ1-pyrroline-5-carboxylate synthase (P5CS) is vital to the synthesis of proline and ornithine, playing an essential role in human health and agriculture. Pathogenic mutations in the P5CS gene (ALDH18A1) lead to neurocutaneous
Externí odkaz:
https://doaj.org/article/4919bfad814545dfb6cfce7ab23adc0d
Autor:
Jun-hao XIAO, Wei QUAN, Qiang XU, Zhi-jun WU, Fang YANG, Kang-jian SUN, Guang-ming LU, Zhi-qiang ZHANG
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 18, Iss 3, Pp 165-170 (2018)
Objective To observe gray matter volume changes and evaluate the relation between gray matter changes and duration of mesial temporal lobe epilepsy (mTLE) patients with different seizure types. Methods A total of 40 patients with mTLE, including 20 w
Externí odkaz:
https://doaj.org/article/0eefeb0b5c5743cc95747d3f0099479a
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 17, Iss 12, Pp 883-890 (2017)
Objective To observe and explore the activation pattern and functional reorganization mechanism of motor cortex in acute ischemic stroke patients. Methods A total of 22 patients with first-ever acute ischemic stroke were included in this study. Funct
Externí odkaz:
https://doaj.org/article/e14a34050597472d81ac7ceaadb8ad6d
Publikováno v:
Chinese Medical Journal, Vol 130, Iss 21, Pp 2591-2600 (2017)
Background: Biotherapy based on human bone marrow-derived mesenchymal stem cells (BMSCs) is currently the focus of research, especially in the field of autologous stem cell transplantation. A novel type of metastasis-associated magnetic resonance (MR
Externí odkaz:
https://doaj.org/article/78d59cf336994205bd916bdddb882962
Autor:
Guang-ming LU, Zhi-qiang ZHANG
Publikováno v:
Chinese Journal of Contemporary Neurology and Neurosurgery, Vol 18, Iss 3, Pp 153-155 (2018)
Over recent 30 years, fMRI has emerged as one of the most popular brain imaging techniques with highly spatiotemporal resolution and noninvasiveness, and has promoted the development of brain science. However, it still faces numerous challenges in th
Externí odkaz:
https://doaj.org/article/dc700d3fe7674c36a7f4c2e74df5bdb0
Publikováno v:
Chinese Medical Journal, Vol 129, Iss 24, Pp 2926-2935 (2016)
Background: The detection of solitary pulmonary nodules (SPNs) that may potentially develop into a malignant lesion is essential for early clinical interventions. However, grading classification based on computed tomography (CT) imaging results remai
Externí odkaz:
https://doaj.org/article/4ab4bf92557e4052b6e7855437bfed2d
Autor:
Lin Ou-yang, Guang-ming Lu
Publikováno v:
Chronic Diseases and Translational Medicine, Vol 1, Iss 2, Pp 96-104 (2015)
Objective: Using a dynamic computed tomographic perfusion (CTP) imaging method to explore the age-related distribution of the microcirculation perfusion function in the vertebral marrow, the bone material density (BMD), and the intervertebral discal
Externí odkaz:
https://doaj.org/article/efa7880d029b43fe89d2337119ce065e