Zobrazeno 1 - 10
of 167
pro vyhledávání: '"Guang‐Xiu Lu"'
Autor:
Jian-Fang Che, Hui-Xia Wu, Si-Cong Zeng, Yue-Ren Wu, Jing Dai, De-Hua Cheng, Fei Gong, Guang-Xiu Lu, Ge Lin, Can Dai
Publikováno v:
Asian Journal of Andrology, Vol 26, Iss 2, Pp 175-182 (2024)
Phospholipase C zeta (PLCζ) is a key sperm-borne oocyte-activating factor that triggers Ca2+ oscillations and the subsequent block to polyspermy following gamete fusion. Mutations in PLCZ1, the gene encoding PLCζ, cause male infertility and intracy
Externí odkaz:
https://doaj.org/article/ff3defbd861a4349a5ed4f941e30b62b
Autor:
Jihong Guo, Wen-Bin He, Lei Dai, Fen Tian, Zhenqing Luo, Fang Shen, Ming Tu, Yu Zheng, Liu Zhao, Chen Tan, Yongteng Guo, Lan-Lan Meng, Wei Liu, Mei Deng, Xinghan Wu, Yu Peng, Shuju Zhang, Guang-Xiu Lu, Ge Lin, Hua Wang, Yue-Qiu Tan, Yongjia Yang
Publikováno v:
HGG Advances, Vol 5, Iss 1, Pp 100256- (2024)
Summary: In this study, we report on mosaic variegated aneuploidy (MVA) syndrome with tetraploidy and predisposition to infertility in a family. Sequencing analysis identified that the CEP192 biallelic variants (c.1912C>T, p.His638Tyr and c.5750A>G,
Externí odkaz:
https://doaj.org/article/67694e929e9e453aa535bdd7f4b671dc
Autor:
Yuan Li, Quan Wen, Jing Hu, Jingnan Liao, Xiangxiu Fan, Huijun Chen, Qi Zhao, Guang-Xiu Lu, Ge Lin, Fei Gong
Publikováno v:
BMC Pregnancy and Childbirth, Vol 23, Iss 1, Pp 1-6 (2023)
Abstract Objective To evaluate the clinical availability and stability of histological endometrial dating as a tool for personalized frozen-thawed embryo transfer (pFET) in patients with repeated implantation failure (RIF) in natural cycles. Methods
Externí odkaz:
https://doaj.org/article/7284ddc729af478c8731f00a4a6376ba
Autor:
Dong-Yan Li, Xiao-Xuan Yang, Chao-Feng Tu, Wei-Li Wang, Lan-Lan Meng, Guang-Xiu Lu, Yue-Qiu Tan, Qian-Jun Zhang, Juan Du
Publikováno v:
Asian Journal of Andrology, Vol 24, Iss 4, Pp 359-366 (2022)
Spermiogenesis is a complex and tightly regulated process, consisting of acrosomal biogenesis, condensation of chromatin, flagellar assembly, and disposal of extra cytoplasm. Previous studies have reported that sperm flagellar 2 (SPEF2) deficiency ca
Externí odkaz:
https://doaj.org/article/ef7599ad93e6460984f29901b6aa9b33
Autor:
Yurong Wang, Ling Liu, Chen Tan, Guiquan Meng, Lanlan Meng, Hongchuan Nie, Juan Du, Guang-Xiu Lu, Ge Lin, Wen-Bin He, Yue-Qiu Tan
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Background: Infertility is a global health concern. MEIOB has been found to be associated with premature ovarian insufficiency (POI) and non-obstructive azoospermia (NOA), but its variants have not been reported in Chinese patients. The aim of this s
Externí odkaz:
https://doaj.org/article/65a1368ddce549be97d248cb97243b58
Autor:
Yuan Li, Quan Wen, Jingnan Liao, Shujuan Ma, Shuoping Zhang, Yifan Gu, Yi Tang, Keli Luo, Xiaoyi Yang, Guang-Xiu Lu, Ge Lin, Fei Gong
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
ObjectiveTo evaluate whether trophectoderm (TE) biopsy differentially influence the level of serum β-human chorionic gonadotropin (β-hCG) with different TE-scored blastocysts transferred in early pregnancy.MethodsThis retrospective cohort study con
Externí odkaz:
https://doaj.org/article/6d67b195b3584e7c8c792c57c9c2aedc
Publikováno v:
Reproductive and Developmental Medicine, Vol 4, Iss 3, Pp 156-162 (2020)
Objective: Overweight and obesity are increasingly epidemic and negatively related to reproductive outcome. The aim of this study was to investigate the advantages of a modified ultra-long downregulation protocol on pregnancy outcomes of patients wit
Externí odkaz:
https://doaj.org/article/8ce44cd3377b45c89a625f38116487b5
Autor:
Yin‐Li Zhang, Wei Zheng, Peipei Ren, Huiling Hu, Xiaomei Tong, Shuo‐Ping Zhang, Xiang Li, Haichao Wang, Jun‐Chao Jiang, Jiamin Jin, Weijie Yang, Lanrui Cao, Yuanlin He, Yerong Ma, Yingyi Zhang, Yifan Gu, Liang Hu, Keli Luo, Fei Gong, Guang‐Xiu Lu, Ge Lin, Heng‐Yu Fan, Songying Zhang
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 12, Pp n/a-n/a (2021)
Abstract Early embryonic arrest and fragmentation (EEAF) is a common phenomenon leading to female infertility, but the genetic determinants remain largely unknown. The Moloney sarcoma oncogene (MOS) encodes a serine/threonine kinase that activates th
Externí odkaz:
https://doaj.org/article/4c2cd6de5312404d872f47f428ad7192
Autor:
Xiao Hu, Wen‐Bin He, Shuo‐Ping Zhang, Ke‐Li Luo, Fei Gong, Jing Dai, Yi Zhang, Zhen‐Xing Wan, Wen Li, Shi‐Min Yuan, Yue‐Qiu Tan, Guang‐Xiu Lu, Ge Lin, Juan Du
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 9, Iss 5, Pp n/a-n/a (2021)
ABSTRACT Background Mosaicism poses challenges for genetic counseling and preimplantation genetic testing for monogenic disorders (PGT‐M). NGS‐based PGT‐M has been extensively used to prevent the transmission of monogenic defects, but it has no
Externí odkaz:
https://doaj.org/article/ddd32b4c9a2e4117888791000cb84b5d
Autor:
Ya‐Xin Zhang, Wen‐Bin He, Wen‐Juan Xiao, Lan‐Lan Meng, Chen Tan, Juan Du, Guang‐Xiu Lu, Ge Lin, Yue‐Qiu Tan
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 4, Pp n/a-n/a (2020)
Abstract Background Premature ovarian insufficiency (POI) is one major cause of female infertility, minichromosome maintenance complex component 8 (MCM8) has been reported to be responsible for POI. Methods Whole‐exome sequencing was performed to i
Externí odkaz:
https://doaj.org/article/2f4d6a6515e24df7a6b5a738ab90684e