Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Guanfang Shi"'
Autor:
Jen Chin Wang, Guanfang Shi, Chi Chen, Ching Wong, Vladimir Gotlieb, Gardith Joseph, Kiron V Nair, Lakshmi Boyapati, Enayati Ladan, James T. Symanowski, Lishi Sun
Publikováno v:
Mediators of Inflammation, Vol 2024 (2024)
We investigated the role of toll-like receptors (TLRs) in inflammatory pathways in Philadelphia chromosome-negative myeloproliferative neoplasms (Ph(−)MPNs). TLR2 expression was increased in ET, PV, and MPN (grouped as (PV + (ET) + MF)), whereas TL
Externí odkaz:
https://doaj.org/article/0bbd7efcd772411a889e3e97d678ed93
Autor:
Jen C Wang, Guanfang Shi, Stacey Baptiste, Maryna Yarotska, Hemant Sindhu, Ching Wong, Madhumati Kalavar, Vladimir Gotlieb, Andrei Bandarchuk, Hui Chen
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0165299 (2016)
Endogenous erythroid colony (EEC) formation is one of the minor criteria for diagnosing polycythemia vera (PV) according to 2008 WHO diagnostic criteria. But EEC requires bone marrow aspiration and sophisticated laboratory procedures; therefore, prac
Externí odkaz:
https://doaj.org/article/bbf472abbe104baf9494e57151db5661
Publikováno v:
Blood. 140:12185-12186
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27a136a28c636ad8bfd04431db49956a
https://doi.org/10.1182/blood-2022-158120
https://doi.org/10.1182/blood-2022-158120
Publikováno v:
European Journal of Haematology. 103:573-577
To make a definite diagnosis of essential thrombocytosis (ET) from reactive thrombocytosis (RT), the most reliable criteria are the presence of driver mutations, namely JAK2, CALR, or MPL gene mutations. In the absence of these driver mutations, so-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cec63edcbe9a9e2e7c571503e3538023
https://doi.org/10.1111/ejh.13323
https://doi.org/10.1111/ejh.13323
Autor:
Ching Wong, Kiron Nair, Preethi Ramachandran, Guanfang Shi, Vladimir Gotlieb, Chi Chen, Gardith Joseph, Maksim Liaukovich, Jen-Chin Wang
Publikováno v:
Blood. 136:31-32
Recent evidence of increased constitutional symptoms and inflammatory cytokines in Philadelphia chromosome negative (Ph (-)) MPN suggests that an inflammatory response is important in the pathogenesis of Ph (-) MPN. Toll-like receptors (TLR), Recepto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43c2965109d4eeeb7982279cff586288
https://doi.org/10.1182/blood-2020-134988
https://doi.org/10.1182/blood-2020-134988
Publikováno v:
Blood. 136:14-15
We previously reported that by flow cytometry study of mononuclear cells (peripheral blood) of IGF-1 R (insulin growth factor -1 receptor) can help in differentiating polycythemia vera (PV) from secondary erythrocytosis (PLoS ONE 11(11): e016529), in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58be182bdc29d7849d01de29a79d95c9
https://doi.org/10.1182/blood-2020-134863
https://doi.org/10.1182/blood-2020-134863
Autor:
Preethi Ramachandran, Vladimir Gotlieb, Karan Josan, Guanfang Shi, Gardith Joseph, Sherif A. Nasr, Jen-Chin Wang
Publikováno v:
Blood. 134:5386-5386
We previously reported that autophagy was defective in classical Philadelphia negative (Ph -) Myeloproliferative Neoplasm (MPN) by demonstrating increased p62, decreased Beclin-1 by RT-PCR and Western Blot (WB) methods and decreased LC3-II by WB (ASH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a91b0aecc9bdee5e7c57c4e3205ee02
https://doi.org/10.1182/blood-2019-127949
https://doi.org/10.1182/blood-2019-127949
Publikováno v:
Blood. 134:5389-5389
We previously reported that assaying blood MNC (Mononuclear cells) IGF-1 levels by Flow cytometry, will be helpful in differentiating Polycythemia vera (PV) from secondarypolycythemia (1). Patients with chronic polycythemia who are negative for JAK2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f837fe4ba95c08064c66b0f9d63d8d7c
https://doi.org/10.1182/blood-2019-123006
https://doi.org/10.1182/blood-2019-123006
Autor:
Craig N. Morrell, Guanfang Shi
Publikováno v:
Thrombosis Research. 127:387-390
Platelets are dynamic cells with activities that extend beyond thrombosis including an important role in initiating and sustaining vascular inflammation. A role for platelets has been described in many physiologic and pathophysiologic processes such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19c8e377f6d5fcbce1e0594c8ebafc9e
https://doi.org/10.1016/j.thromres.2010.10.019
https://doi.org/10.1016/j.thromres.2010.10.019
Publikováno v:
Blood. 132:3069-3069
Introduction: We and others have reported markedly increased ROS formation in primary myelofibrosis (MF) including post-ET or PV-MF when compared with essential thrombocytosis (ET), polycythemia vera (PV) and normal controls. A growing body of eviden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b1a2bfc7b95a159bb1e0dbd5f9651c84
https://doi.org/10.1182/blood-2018-99-112406
https://doi.org/10.1182/blood-2018-99-112406