Výsledky vyhledávání - "Guan-Qun Xie"

Akademický článek

The effects of Jieduquyuzishen prescription-treated rat serum on the BAFF/BAFF-R signal pathway.

Autor: De-Hong Wu, Li Xu, Cheng-Ping Wen, Guan-Qun Xie, Jin-Jun Ji, Jie-Li Pan, Yi-Feng Jiao, Yong-Sheng Fan

Publikováno v: PLoS ONE, Vol 10, Iss 2, p e0118462 (2015)

Systemic lupus erythematosus (SLE) is a chronic inflammatory disease mainly characterized by B cell hyperactivity. Glucocorticoid (GC) is widely used in SLE for its potent anti-inflammatory and immunosuppressive effects. Despite its important clinica

Externí odkaz: https://doaj.org/article/38f8392c33214630a05188de725b70a2

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Oxidative stress-induced aberrant lipid metabolism is an important causal factor for dysfunction of immunocytes from patients with systemic lupus erythematosus

Autor: Suzhen Hong, Xianlin Han, Lu Lu, Haichang Li, Wenqing Luo, Changfeng Hu, Jida Zhang, Guan-Qun Xie, Zhijun Xie, Yu Du, Chengping Wen

Publikováno v: Free Radical Biology and Medicine. 163:210-219

There exist close relationships among oxidative stress, dyslipidaemia, inflammation, and autoimmune response in patients with systemic lupus erythematosus (SLE). Dysfunction and/or dysregulation of immunocytes is one of the major characteristics of S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dba693ee84986559f8199cf6bfa0dca3
https://doi.org/10.1016/j.freeradbiomed.2020.12.006

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Metabolic Disturbance and Th17/Treg Imbalance Are Associated With Progression of Gingivitis

Autor: Weijie Wang, Du Yu, Yongsheng Fan, Guan-Qun Xie, Ting Zhao, Li Xu, Xinchang Wang, Huiqing Lv, Shuhao Lu

Publikováno v: Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology

ObjectiveThis study sought to explore the role of metabolic disturbance in immunoregulation of gingivitis targeting T helper 17 cells (Th17)/regulatory T cell (Treg).Materials and MethodsA total of 20 gingivitis patients and 19 healthy volunteers wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e5c31b657e32b4f7d61eaa8565bfb71
https://www.frontiersin.org/articles/10.3389/fimmu.2021.670178/full

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Epigallocatechin Gallate Protects against MNNG-Induced Precancerous Lesions of Gastric Carcinoma in Rats via PI3K/Akt/mTOR Pathway

Autor: Meiya Li, Feiye Zhu, Yanli Xu, Fangming Chen, Guan-Qun Xie, Jieli Pan

Publikováno v: Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2021 (2021)

Objective. To evaluate the therapeutic effect of epigallocatechin gallate (EGCG) on precancerous lesions of gastric carcinoma (PLGC) and to determine whether EGCG protects against PLGC by regulating PI3K/Akt/mTOR pathway. Methods. Twenty-four male Wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e37f2084449aa590844f1ae36d41061f
https://pubmed.ncbi.nlm.nih.gov/33628319

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Potential Molecular Mechanisms of Zhibai Dihuang Wan in Systemic Lupus Erythematosus Based on Network Biology

Autor: Min-Hong Zhong, Yongsheng Fan, Rui-Fei Xie, Ting Zhao, Zi Yang, Guan-Qun Xie

Publikováno v: Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2020 (2020)

Systemic lupus erythematosus (SLE) is a refractory autoimmune disease. Zhibai Dihuang Wan (ZDW) has frequently been used for treating SLE in China and been proved to have a prominent role in decreasing SLE patients’ morality rate. However, the acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c079f0dd9be6f0dedf8340c38b2926d
http://europepmc.org/articles/PMC7178533

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Jieduquyuziyin Prescription alleviates hepatic gluconeogenesis via PI3K/Akt/PGC-1α pathway in glucocorticoid-induced MRL/lpr mice

Autor: Yongsheng Fan, Shan Wu, Lina Ji, Dan-qing Fu, Guan-Qun Xie, Jie Bao, Si-jia Fang

Publikováno v: Journal of Ethnopharmacology. 284:114815

Ethnopharmacological relevance Jieduquyuziyin prescription (JP) is a traditional Chinese medicine (TCM) formula. According to both TCM theory and more than a decade of clinical practice, JP has been testified to be effective for systemic lupus erythe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4918bfeaf3f04ae9764cf1ad3d65f509
https://doi.org/10.1016/j.jep.2021.114815

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The Pungent and Hot Chinese Herbs Cause Heat Syndrome in Rats by Affecting the Regulatory T Cells

Autor: Yongsheng Fan, Dehong Wu, Jia Zhou, Li Xu, Guan-Qun Xie

Publikováno v: Evidence-based Complementary and Alternative Medicine : eCAM
Evidence-Based Complementary and Alternative Medicine, Vol 2019 (2019)

Heat syndrome is a folk saying in China, which is used to describe people with symptoms such as aphtha, oral ulcer, glossitis, swelling and aching of gingiva, and dry eye. Aconitum carmichaelii Debx. (A), Zingiber officinale Rosc. (Z), and Cinnamomum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa5118e7eed3a4e9281485ae2bfa0ba
https://pubmed.ncbi.nlm.nih.gov/31360212

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[Effect of Modified Leweiyin Recipe on SGC-7901 Human Gastric Cancer Cells from Crosstalk between NF-κB and STAT3]

Autor: Fei-Ye, Zhu, Guan-Qun, Xie, Yong-Sheng, Zhang, Shan, Xu

Publikováno v: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine. 37(2)

Objective To observe the effect of Modified Leweiyin Recipe (MLR) on nuclear factor kappa B (NF-κB) and crosstalk between signal transducers and activators of transcription 3 (STAT3) in SGC-7901 human gastric cancer cells. Methods SGC-7901 human gas

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::60e51dd0d04f4234f9b3471d64760343
https://pubmed.ncbi.nlm.nih.gov/30650279

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