Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Guan-Qi Gao"'
Autor:
Rui-Meng Yang, Shi-Yang Song, Feng-Yao Wu, Rui-Feng Yang, Yan-Ting Shen, Ping-Hui Tu, Zheng Wang, Jun-Xiu Zhang, Feng Cheng, Guan-Qi Gao, Jun Liang, Miao-Miao Guo, Liu Yang, Yi Zhou, Shuang-Xia Zhao, Ming Zhan, Huai-Dong Song
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract The pathogenesis of thyroid dysgenesis (TD) is not well understood. Here, using a combination of single-cell RNA and spatial transcriptome sequencing, we identify a subgroup of NF-κB-activated thyrocytes located at the center of thyroid tis
Externí odkaz:
https://doaj.org/article/de96cbfe3add49e090d84426e4f595ec
Publikováno v:
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Graves’ disease (GD) is one of the most common autoimmune thyroid diseases (AITDs) in humans, and thyrotropin receptor antibody (TRAb) is a characterized autoantibody in GD. The use of radioactive iodine therapy (RAI) for GD tre
Externí odkaz:
https://doaj.org/article/50b78bfb6f954331bf89381fdb3afc5a
Autor:
Shuang-Xia Zhao, Wei Liu, Ming Zhan, Zhi-Yi Song, Shao-Ying Yang, Li-Qiong Xue, Chun-Ming Pan, Zhao-Hui Gu, Bing-Li Liu, Hai-Ning Wang, Liming Liang, Jun Liang, Xiao-Mei Zhang, Guo-Yue Yuan, Chang-Gui Li, Ming-Dao Chen, Jia-Lun Chen, Guan-Qi Gao, Huai-Dong Song, China Consortium for the Genetics of Autoimmune Thyroid Disease
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e57758 (2013)
To pinpoint the exact location of the etiological variant/s present at 1q21.1 harboring FCRL1-5 and CD5L genes, we carried out a refined association study in the entire FCRL region in 1,536 patients with Graves' disease (GD) and 1,516 sex-matched con
Externí odkaz:
https://doaj.org/article/4d47f18e24bb4837a4327b688e987d21
Autor:
Shuang-Xia Zhao, Chun-Ming Pan, Huang-Ming Cao, Bing Han, Jing-Yi Shi, Jun Liang, Guan-Qi Gao, Yong-De Peng, Qing Su, Jia-Lun Chen, Jia-Jun Zhao, Huai-Dong Song
Publikováno v:
PLoS ONE, Vol 5, Iss 3, p e9821 (2010)
To determine whether genetic heterogeneity exists in patients with Graves' disease (GD), the cytotoxic T-lymphocyte associated 4 (CTLA-4) gene, which is implicated a susceptibility gene for GD by considerable genetic and immunological evidence, was u
Externí odkaz:
https://doaj.org/article/7bf1d93f632f4717aa4a5b216e9715d1
Autor:
Chun-Lin Zuo, Sha-Sha Yu, Jun Liang, Guan-Qi Gao, Hui-Jun Xie, Zheng Zhou, Huai-Dong Song, Fei-Fei Yuan, Yu-Ru Ma, Wen-Hua Du, Feng Sun, Qian-Yue Zhang, Chang-Run Zhang, Shuang-Xia Zhao, Xiao-Ping Ye, Wei Liu, Lu Li, Guoyue Yuan, Ying-Xia Ying
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 105:e2600-e2608
Context Hashimoto’s thyroiditis (HT) and Graves’ disease (GD) are the 2 main autoimmune thyroid diseases that have both similarities and differences. Determining the genetic basis that distinguishes HT from GD is key for a better understanding of
Publikováno v:
BMC Endocrine Disorders
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Endocrine Disorders, Vol 21, Iss 1, Pp 1-9 (2021)
BackgroundGraves’ disease (GD) is one of the most common autoimmune thyroid diseases (AITDs) in humans, and thyrotropin receptor antibody (TRAb) is a characterized autoantibody in GD. The use of radioactive iodine therapy (RAI) for GD treatment is
Autor:
Qian-Yue, Zhang, Wei, Liu, Lu, Li, Wen-Hua, Du, Chun-Lin, Zuo, Xiao-Ping, Ye, Zheng, Zhou, Fei-Fei, Yuan, Yu-Ru, Ma, Feng, Sun, Sha-Sha, Yu, Hui-Jun, Xie, Chang-Run, Zhang, Ying-Xia, Ying, Guo-Yue, Yuan, Guan-Qi, Gao, Jun, Liang, Shuang-Xia, Zhao, Huai-Dong, Song
Publikováno v:
The Journal of clinical endocrinology and metabolism. 105(10)
Autor:
Cui-Cui Guo, Xiao-Ping Ye, Yue-Yue Wan, Ke-Yi Song, Feng Sun, Bing Han, Guan-Qi Gao, Yu-Ru Ma, Wei Liu, gang Chen, Wen-Bin Zhu, Jun-Xiu Zhang, Chang-Yi Yang, Lele Zhang, Liu Yang, Qian-Yue Zhang, Man-Man Zhang, Huai-Dong Song, Shuang-Xia Zhao
Publikováno v:
European Journal of Endocrinology
Objective Congenital hypothyroidism (CH), the most common neonatal metabolic disorder, is characterized by impaired neurodevelopment. Although several candidate genes have been associated with CH, comprehensive screening of causative genes has been l
Autor:
Zheng Zhou, Xiao-Ping Ye, Guan-Qi Gao, Ying-Xia Ying, Qian-Yue Zhang, Hui-Jun Xie, Feng Sun, Fei-Fei Yuan, Jun Liang, Wei Liu, Shuang-Xia Zhao, Yu-Ru Ma, Lu Li, Chun-Lin Zuo, Sha-Sha Yu, Guoyue Yuan, Chang-Run Zhang, Huai-Dong Song, Wen-Hua Du
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 105:e3840-e3841
Autor:
Shuang-Xia Zhao, Wen-Hua Du, Zhi-Yi Song, Xiao-Ping Ye, Guan-Qi Gao, Xiao-Mei Zhang, Sheng-Xian Li, Fengling Chen, Hai-Ning Wang, Wei Liu, Fei-Fei Yuan, Lele Zhang, Huai-Dong Song, Qian-Yue Zhang, Man-Man Zhang, Yu-Ru Ma, Jun Liang
Publikováno v:
Clinical endocrinology. 89(6)
OBJECTIVE We aimed to investigate the six susceptibility loci of GD identified from European population in Chinese Han population and further to estimate the genetic heterogeneity of them in stratification of our GD patients. DESIGN Dense mapping stu