Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Guan-Lin Sun"'
Autor:
Jian-Hua Ni, Ting-Dong Zhang, Guan-Lin Sun, Xiu-Shong Li, Wei Tang, Kan-Qi Yang, Qian-Yao Qiu, Zhi-Wen Fang, Yan-Ting Wang, Peng Zhang, Zhen-Yi Wang, Zhu Chen, Li Zhou, Jun Zhu, Yu Chen, Shu-Min Xiong, Guo-Qiang Chen, Zhi-Xiang Shen, Jun Ma, Sai-Juan Chen
Publikováno v:
Blood. 89:3354-3360
The therapeutic effect of arsenic trioxide (As2O3 ) in the treatment of acute promyelocytic leukemia (APL) was evaluated among 15 APL patients at relapse after all-trans retinoic acid (ATRA) induced and chemotherapy maintained complete remission (CR)
Autor:
Xue-Geng Shi, Gui-Ying Si, Xiu-Shong Li, Hao-Jie Zhong, Sai-Juan Chen, Guan-Lin Sun, Shu-Ming Xong, Ting-Dong Zhang, Peng Zhang, Claude Gazin, Tomoki Naoe, Zhen-Yi Wang, Jun Zhu, Jian-Hua Ni, Xiao-Long Jin, Guo-Qiang Chen, Jun Ma, Zhi-Xiang Shen, Zhu Chen, Wei Tang
Publikováno v:
Blood. 88:1052-1061
It has been shown recently in China that arsenic trioxide (As2O3) is a very effective treatment for acute promyelocytic leukemia (APL). APL patients resistant to all-trans retinoic acid (ATRA) and conventional chemotherapy can still respond to AS2O3.
Autor:
Jia-Hua Tong, S. Dong, Zhen-Yi Wang, Jin-Ren Cai, Christian-Jacques Larsen, Yu Wu, Shu-Rong Chen, Zhu Chen, Guan-Lin Sun, Roland Berger, Sai-Juan Chen, Jie-Ping Geng
Publikováno v:
Genes, Chromosomes and Cancer. 6:133-139
DNA studies of the translocation t(15;17) in acute promyelocytic leukemia (APL) have shown that the retinoic acid receptor alpha (RARA) gene on chromosome 17 is juxtaposed to the promyelocytic leukemia (PML) gene on chromosome 15. The PML breakpoints
Autor:
Ji Zhang, Huiping Sun, Yanzhi Du, Guo-Qiang Chen, Ying-Li Wu, Kankan Wang, Guan-Lin Sun, Zhu Chen, Sai-Juan Chen, Tong Yin
Publikováno v:
Blood. 104(13)
Imatinib (STI571, Gleevec) is a tailored drug for chronic myelogenous leukemia (CML), whereas arsenic compounds were used as ancient remedies for CML with certain efficacy. The aim of this study was to investigate the potential benefit of combination
Publikováno v:
Zhongguo shi yan xue ye xue za zhi. 12(1)
To investigate the effects of TGF-beta1 on biological characteristics of hematopoietic progenitor cells (HPC) in umbilical cord blood (UCB) during ex-vivo expansion and feasibility of using it for expansion of UCB HPC, different concentrations of TGF
Publikováno v:
Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi. 24(11)
To investigate the synergistic effect of As(2)S(2) and STI 571 on K562 cells and its mechanism.The inhibitive effect of As(2)S(2) on the proliferation of K562 cells was determined by cell number count. Cell apoptosis was assessed by flow cytometry, D
Publikováno v:
Zhongguo shi yan xue ye xue za zhi. 11(6)
This study was to investigate dynamics of biological properties of CD133(+) cells from human umbilical cord blood (UCB) during short-term culture containing the combination of hematopoietic growth factors and the feasibility of in vitro expansion of
Publikováno v:
Zhonghua zhong liu za zhi [Chinese journal of oncology]. 25(3)
To investigate the apoptotic inducing effect of As(2)S(2) on K562 cells.The apoptotic inducing effect of As(2)S(2) on K562 cells was determined by flow cytometry, DNA fragmentation analysis and morphology observation. Expression of protein was determ
Publikováno v:
Zhongguo shi yan xue ye xue za zhi. 9(1)
In this research, the effect of novel retinoid SX-116 on acute promyelocytic leukemia cell line NB4 was studied in vitro. Cell proliferation, cell morphological characters, flow cytometry, DNA electrophoresis and RT-PCR were observational parameters.
Publikováno v:
Acta pharmacologica Sinica. 23(11)
To investigate the apoptotic effect of As2S2 on K562 cells and its mechanism.The effect of As2S2 on proliferation of K562 cells was determined by counting the number of cells. Apoptosis was assessed by flow cytometry, DNA fragmentation analysis, and