Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Guan-Liang Cao"'
Autor:
Guan Liang Cao, Jelena Platisa, Davide Raccuglia, Vincent A. Pieribone, Michael N. Nitabach, Michael Kunst
Publikováno v:
Cell. 154(4):904-913
SummaryNervous systems process information by integrating the electrical activity of neurons in complex networks. This motivates the long-standing interest in using optical methods to simultaneously monitor the membrane potential of multiple genetica
Autor:
Guan-Liang Cao, Pei Tsai, Alan S. Cross, Bruce Tomczuk, Paul Shapiro, Peter D. Suzdak, Gerald M. Rosen
Publikováno v:
Current Microbiology. 64:379-384
Macrophages, upon phagocytosing endospores of Bacillus anthracis, up-regulate the expression of the immunological isoform of nitric oxide synthase, NOS 2, concomitant with production of nitric oxide (NO•) from metabolism of l-arginine. We have prev
Autor:
Xue Hong Xu, Gui Fang Yan, Meng Meng Xu, Guan Liang Cao, Chu Yu Zhang, Odell Jones, Hai-Ping He
Publikováno v:
Key Engineering Materials. :349-355
Calcium carbonate is often used as an efficient antacid that absorbs and neutralizes stomach acid while providing calcium for healthy bones. Taking advantage of the lack of adverse side effects of calcium, new drug delivery systems consisting of drug
Autor:
John Weaver, Les Baillie, Guan-Liang Cao, Tae Jin Kang, Kimberly W. Raines, Stephen Hibbs, Gerald M. Rosen, Pei Tsai, Alan S. Cross
Publikováno v:
Infection and Immunity. 75:3894-3901
The ability of the endospore-forming, gram-positive bacterium Bacillus anthracis to survive in activated macrophages is key to its germination and survival. In a previous publication, we discovered that exposure of primary murine macrophages to B. an
Publikováno v:
Biochemical Journal. 397:329-336
nNOS (neuronal nitric oxide synthase) is a constitutively expressed enzyme responsible for the production of NO• from L-arginine and O2. NO• acts as both an intra- and an inter-cellular messenger that mediates a variety of signalling pathways. Pr
Autor:
Pei Tsai, Kimberly W. Raines, Alan S. Cross, Guan-Liang Cao, Gerald M. Rosen, Tae Jin Kang, John Weaver, Stephen Hibbs, Les Baillie
Publikováno v:
Infection and Immunity. 74:2268-2276
The spore-forming, gram-positive bacterium Bacillus anthracis , the causative agent of anthrax, has achieved notoriety due to its use as a bioterror agent. In the environment, B. anthracis exists as a dormant endospore. Upon infection, germination of
Autor:
Linda J. Roman, John Weaver, Anatoly A. Starkov, Gerald M. Rosen, Sovitj Pou, Guan Liang Cao, Pei Tsai
Publikováno v:
Biochemical Pharmacology. 69:971-979
Tetrahydrobiopterin (H(4)B) in the absence of L-arginine has been shown to be an important factor in promoting the direct formation of hydrogen peroxide (H(2)O(2)) at the expense of superoxide (O(2)(*-)) by neuronal nitric oxide synthase (NOS1) [Rose
Autor:
Marian J. Jackson, Joseph B. Domachowske, Supatra Porasuphatana, Bin Zhang, Gerald M. Rosen, Guan-Liang Cao
Publikováno v:
Analytical Biochemistry. 286:198-205
Nitric oxide (NO*), generated by nitric oxide synthase (NOS II) from immunostimulated cells during infection, plays an important role in host immune defense against microbial invasion. The impact of different rates of NO* production on host cell func
Autor:
Howard J. Halpern, Sovitj Pou, Bradley E. Sturgeon, Daniel J. Hassett, Gerald M. Rosen, Michael J. Barber, Myron S. Cohen, Kennyatta Cosby, Bradley E. Britigan, Guan Liang Cao
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 2. :297-300
One of the difficult tasks confronting the study of free radicals in biology is the inability to measure “on line” injury to a biological target, while characterizing the reactive species responsible for the toxic event. This is particularly rele
Autor:
Bin Zhang, Roman E. Ratych, Michelle Centra, Harry L. Malech, Gerald M. Rosen, Joseph B. Domachowske, Guan Liang Cao
Publikováno v:
Immunology Letters. 58:113-120
We have recently demonstrated that endothelial cells cultured on Gelfoam blocks, but not monolayer matrices can phagocytose and kill Staphylococcus aureus. Experiments determined that penicillin G, included in the endothelial cell growth medium, indu