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Non-canonical Wnt signaling triggered by WNT2B drives adrenal aldosterone production.

Autor: Borges KS; Division of Endocrinology, Boston Children's Hospital, Boston, MA, 02115, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA., Little DW 3rd; Doctoral Program in Cancer Biology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, MI, 48109, USA., Magalhães TA; Department of Cell Biology, Harvard Medical School, Boston, MA, 02115, USA., Ribeiro C; Division of Endocrinology, Boston Children's Hospital, Boston, MA, 02115, USA., Dumontet T; Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, MI, 48109, USA., Lapensee C; Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, MI, 48109, USA., Basham KJ; Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, 84112, USA., Seth A; Division of Endocrinology, Boston Children's Hospital, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, Cambridge MA, 02142., Azova S; Division of Endocrinology, Boston Children's Hospital, Boston, MA, 02115, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA., Guagliardo NA; Department of Pharmacology, University of Virginia, Charlottesville, VA, 22908-0735, USA., Barrett PQ; Department of Pharmacology, University of Virginia, Charlottesville, VA, 22908-0735, USA., Berber M; Division of Endocrinology, Boston Children's Hospital, Boston, MA, 02115, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA., O'Connell AE; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA.; Division of Newborn Medicine, Boston Children's Hospital, Boston, MA, 02115, USA., Turcu AF; Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, MI, 48109, USA., Lerario AM; Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, MI, 48109, USA., Mohan DR; Doctoral Program in Cancer Biology, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, MI, 48109, USA.; Medical Scientist Training Program, University of Michigan, Ann Arbor, MI 48109, USA., Rainey W; Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, MI, 48109, USA.; Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, MI, 48109, USA., Carlone DL; Division of Endocrinology, Boston Children's Hospital, Boston, MA, 02115, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA.; Harvard Stem Cell Institute, Cambridge, MA, 02138, USA., Hirschhorn JN; Division of Endocrinology, Boston Children's Hospital, Boston, MA, 02115, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, Cambridge MA, 02142., Salic A; Department of Cell Biology, Harvard Medical School, Boston, MA, 02115, USA., Breault DT; Division of Endocrinology, Boston Children's Hospital, Boston, MA, 02115, USA.; Department of Pediatrics, Harvard Medical School, Boston, MA, 02115, USA.; Broad Institute of MIT and Harvard, Cambridge MA, 02142.; Harvard Stem Cell Institute, Cambridge, MA, 02138, USA., Hammer GD; Department of Internal Medicine, Division of Metabolism, Endocrinology, and Diabetes, University of Michigan, Ann Arbor, MI, 48109, USA.; Endocrine Oncology Program, Rogel Cancer Center, University of Michigan, Ann Arbor, MI, 48109, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Aug 24. Date of Electronic Publication: 2024 Aug 24.

Rosette morphology in zona glomerulosa formation and function.

Autor: Leng S; Division of Endocrinology, Boston Children's Hospital, Boston, MA, 02115, USA. Electronic address: sining.leng@gmail.com., Carlone DL; Division of Endocrinology, Boston Children's Hospital, Boston, MA, 02115, USA. Electronic address: diana.carlone@childrens.harvard.edu., Guagliardo NA; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, VA, USA. Electronic address: Nag4g@virginia.edu., Barrett PQ; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, VA, USA. Electronic address: Pqb4b@virginia.edu., Breault DT; Division of Endocrinology, Boston Children's Hospital, Boston, MA, 02115, USA. Electronic address: david.breault@childrens.harvard.edu.

Publikováno v: Molecular and cellular endocrinology [Mol Cell Endocrinol] 2021 Jun 15; Vol. 530, pp. 111287. Date of Electronic Publication: 2021 Apr 21.

Pannexin 1 channels in renin-expressing cells influence renin secretion and blood pressure homeostasis.

Autor: DeLalio LJ; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Masati E; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Mendu S; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Ruddiman CA; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Yang Y; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA; Department of Pharmacology, Dalian Medical University, Dalian, China., Johnstone SR; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Milstein JA; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Keller TCS 4th; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA; Department of Molecular Physiology and Biophysics, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Weaver RB; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Guagliardo NA; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Best AK; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Ravichandran KS; Department of Microbiology, Immunology, and Cancer, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Bayliss DA; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Sequeira-Lopez MLS; Pediatric Center of Excellence in Nephrology, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Sonkusare SN; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA; Department of Molecular Physiology and Biophysics, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Shu XH; Department of Pharmacology, Dalian Medical University, Dalian, China., Desai B; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Barrett PQ; Department of Pharmacology, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Le TH; Department of Medicine, Division of Nephrology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA., Gomez RA; Pediatric Center of Excellence in Nephrology, University of Virginia School of Medicine, Charlottesville, Virginia, USA., Isakson BE; Robert M. Berne Cardiovascular Research Center, University of Virginia School of Medicine, Charlottesville, Virginia, USA; Department of Molecular Physiology and Biophysics, University of Virginia School of Medicine, Charlottesville, Virginia, USA. Electronic address: brant@virginia.edu.

Publikováno v: Kidney international [Kidney Int] 2020 Sep; Vol. 98 (3), pp. 630-644. Date of Electronic Publication: 2020 May 21.

Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes.

Autor: Guagliardo NA; Departments of Pharmacology, Charlottesville, VA, USA., Klein PM; Departments of Pharmacology, Charlottesville, VA, USA.; Neuroscience Graduate Program, University of Virginia, Charlottesville, VA, USA., Gancayco CA; Research Computing, University of Virginia, Charlottesville, VA, USA., Lu A; Departments of Pharmacology, Charlottesville, VA, USA.; Neuroscience Graduate Program, University of Virginia, Charlottesville, VA, USA., Leng S; Division of Endocrinology, Boston Children's Hospital, Boston, MA, USA., Makarem RR; Departments of Pharmacology, Charlottesville, VA, USA., Cho C; Departments of Pharmacology, Charlottesville, VA, USA., Rusin CG; Department of Pediatrics-Cardiology, Baylor College of Medicine, and Harvard Stem Cell Institute, Cambridge, MA, USA., Breault DT; Division of Endocrinology, Boston Children's Hospital, Boston, MA, USA., Barrett PQ; Departments of Pharmacology, Charlottesville, VA, USA., Beenhakker MP; Departments of Pharmacology, Charlottesville, VA, USA. mpb5y@virginia.edu.; Neuroscience Graduate Program, University of Virginia, Charlottesville, VA, USA. mpb5y@virginia.edu.

Publikováno v: Nature communications [Nat Commun] 2020 Apr 03; Vol. 11 (1), pp. 1679. Date of Electronic Publication: 2020 Apr 03.