Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Guadalupe Ortiz-Muñoz"'
Autor:
Guadalupe Ortiz-Muñoz, Mark Looney
Publikováno v:
Bio-Protocol, Vol 5, Iss 12 (2015)
The intratracheal instillation technique is used to deliver a variety of agents to the lungs ranging from pathogens (bacteria, viruses), toxins, to therapeutic agents. To model lung inflammation and injury, LPS can be administrated via intranasal, in
Externí odkaz:
https://doaj.org/article/e1a5a490cb134a10ad730973006ec91c
Autor:
Guadalupe Ortiz-Muñoz, Mark Looney
Publikováno v:
Bio-Protocol, Vol 5, Iss 12 (2015)
Transfusion-related acute lung injury (TRALI) is defined as acute lung injury that occurs within 6 hours of a blood product transfusion. TRALI continues to be a leading cause of transfusion-related mortality and we have developed a mouse model of TRA
Externí odkaz:
https://doaj.org/article/69935781ef6d488993f99455659a8d25
Autor:
Beñat Mallavia, Ainhoa Oguiza, Oscar Lopez-Franco, Carlota Recio, Guadalupe Ortiz-Muñoz, Iolanda Lazaro, Virginia Lopez-Parra, Jesus Egido, Carmen Gomez-Guerrero
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66754 (2013)
Immunity contributes to arterial inflammation during atherosclerosis. Oxidized low-density lipoproteins induce an autoimmune response characterized by specific antibodies and immune complexes in atherosclerotic patients. We hypothesize that specific
Externí odkaz:
https://doaj.org/article/eef71a76a03d448188cc0ba4f7e51e08
Autor:
Guadalupe Ortiz-Muñoz, Markus Brown, Catherine B. Carbone, Ximo Pechuan-Jorge, Vincent Rouilly, Henrik Lindberg, Alex T. Ritter, Gautham Raghupathi, Qianbo Sun, Tess Nicotra, Shreya R. Mantri, Angela Yang, Jonas Doerr, Deepti Nagarkar, Spyros Darmanis, Benjamin Haley, Sanjeev Mariathasan, Yulei Wang, Carlos Gomez-Roca, Carlos Eduardo de Andrea, David Spigel, Thomas Wu, Lelia Delamarre, Johannes Schöneberg, Zora Modrusan, Richard Price, Shannon J. Turley, Ira Mellman, Christine Moussion
Publikováno v:
Nature.
The immune phenotype of a tumour is a key predictor of its response to immunotherapy1–4. Patients who respond to checkpoint blockade generally present with immune-inflamed5–7 tumours that are highly infiltrated by T cells. However, not all inflam
Autor:
Jennifer J. Tian, Mary Ellen Kleinhenz, Serena Ranucci, Colin Valet, Emma Lefrançais, Michelle Yu, Peter M. Haggie, Kristin M. Wang, Mark R. Looney, Nicholas Kwaan, Fadi T. Khasawneh, Zhe Liu, Guadalupe Ortiz-Muñoz, Diana Dawson, Alan S. Verkman, Beñat Mallavia
Publikováno v:
The Journal of clinical investigation, vol 130, iss 4
J Clin Invest
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2020, 130 (4), pp.2041-2053. ⟨10.1172/JCI129635⟩
J Clin Invest
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2020, 130 (4), pp.2041-2053. ⟨10.1172/JCI129635⟩
Cystic fibrosis (CF) lung disease is characterized by an inflammatory response that can lead to terminal respiratory failure. The cystic fibrosis transmembrane conductance regulator (CFTR) is mutated in CF, and we hypothesized that dysfunctional CFTR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c23a51ad3f74f770f77a2c31a11111
https://escholarship.org/uc/item/0dx571vd
https://escholarship.org/uc/item/0dx571vd
Autor:
Mark R. Looney, Guadalupe Ortiz-Muñoz
Publikováno v:
Bio-protocol. 5(12)
Transfusion-related acute lung injury (TRALI) is defined as acute lung injury that occurs within 6 hours of a blood product transfusion. TRALI continues to be a leading cause of transfusion-related mortality and we have developed a mouse model of TRA
Autor:
David J. Ross, Mark R. Looney, Ariss Derhovanessian, Guadalupe Ortiz-Muñoz, John A. Belperio, David M. Sayah, Beñat Mallavia, Rajan Saggar, Jason D. Christie, Fengchun Liu, Abbas Ardehali, Axelle Caudrillier, Joseph P. Lynch, Lorraine B. Ware
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 191:455-463
Primary graft dysfunction (PGD) causes early mortality after lung transplantation and may contribute to late graft failure. No effective treatments exist. The pathogenesis of PGD is unclear, although both neutrophils and activated platelets have been
Autor:
Emily E. Thornton, Fengchun Liu, Mark B. Headley, Mark R. Looney, David M. Sayah, Guadalupe Ortiz-Muñoz, Emmanuelle Passegué, Tovo David, Matthew F. Krummel, Beñat Mallavia, Shaun R. Coughlin, Axelle Caudrillier, Andrew D. Leavitt, Emma Lefrançais
Publikováno v:
Nature
Nature, Nature Publishing Group, 2017, 544 (7648), pp.105-109. ⟨10.1038/nature21706⟩
Nature, Nature Publishing Group, 2017, 544 (7648), pp.105-109. ⟨10.1038/nature21706⟩
Platelets are critical for haemostasis, thrombosis, and inflammatory responses, but the events that lead to mature platelet production remain incompletely understood. The bone marrow has been proposed to be a major site of platelet production, althou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aa031e49b4f8ac623d4f4f4370ac1dc
https://hal-cnrs.archives-ouvertes.fr/hal-02997985
https://hal-cnrs.archives-ouvertes.fr/hal-02997985
Autor:
Virginia Lopez-Parra, Carlota Recio, Jesús Egido, Iolanda Lázaro, Susann G. Schindler, Beñat Mallavia, Oscar Lopez-Franco, Reinhard Depping, Ainhoa Oguiza, Guadalupe Ortiz-Muñoz, Carmen Gomez-Guerrero
Publikováno v:
The American Journal of Pathology. 182:1910-1921
Atherosclerosis is a chronic inflammatory disease of the arterial wall. NF-κB is a major regulator of inflammation that controls the expression of many genes involved in atherogenesis. Activated NF-κB was detected in human atherosclerotic plaques,
Autor:
Carmen Gomez-Guerrero, Oscar Lopez-Franco, Julia Blanco, Jesús Egido, Beñat Mallavia, Guadalupe Ortiz-Muñoz, Ainhoa Oguiza, Carlota Recio, Virginia Lopez-Parra, Falk Nimmerjahn
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
instname
Among patients with diabetes, increased production of immunoglobulins against proteins modified by diabetes is associated with proteinuria and cardiovascular risk, suggesting that immune mechanisms may contribute to the development of diabetes compli