Genuine antiplasticizing effect of water on a glass-former drug

Autor: Guadalupe N. Ruiz, Michela Romanini, Astrid Hauptmann, Thomas Loerting, Evgenyi Shalaev, Josep Ll. Tamarit, Luis C. Pardo, Roberto Macovez

Publikováno v: Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)

Abstract Water is the most important plasticizer of biological and organic hydrophilic materials, which generally exhibit enhanced mechanical softness and molecular mobility upon hydration. The enhancement of the molecular dynamics upon mixing with w

Externí odkaz: https://doaj.org/article/206172ee526846c7a8f67c7d23b70070

Tuning molecular dynamics by hydration and confinement: Antiplasticizing effect of water in hydrated prilocaine nanoclusters

Autor: Luis Carlos Pardo, Guadalupe N. Ruiz, Izaskun Combarro-Palacios, Roberto Macovez, Gustavo Ariel Schwartz, Silvina Cerveny, Sylvia E. McLain

Publikováno v: UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
Recercat. Dipósit de la Recerca de Catalunya
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Digital.CSIC. Repositorio Institucional del CSIC

In glass-forming substances, the addition of water tends to produce the effect of lowering the glass transition temperature, T. In a previous work by some of us (Ruiz et al., Sci. Rep., 2017, 7, 7470) we reported on a rare anti-plasticizing effect of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b62968c44429627dbaf215f6d2d62cc0
http://hdl.handle.net/2117/177201

Pressure-induced transformations in LiCl - H2O at 77 K

Autor: Guadalupe N. Ruiz, Livia E. Bove, Horacio R. Corti, Thomas Loerting

Publikováno v: Physical Chemistry Chemical Physics
Physical Chemistry Chemical Physics, Royal Society of Chemistry, 2014, pp.1. ⟨10.1039/C4CP01786B⟩
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Physical Chemistry Chemical Physics, 2014, pp.1. ⟨10.1039/C4CP01786B⟩

A systematic study of the properties of high-density amorphous ice (HDA) in the presence of increasing amounts of salt is missing, especially because it is challenging to avoid ice crystallization upon cooling the pressurized liquid. In order to be a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1918abff755fc427556b0e4b1a2fb369
https://hal.archives-ouvertes.fr/hal-01050527