Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Guadalupe J. Jasso"'
Autor:
Guadalupe J Jasso, Alok Jaiswal, Mukund Varma, Tyler Laszewski, Angelo Grauel, Abdifatah Omar, Nilsa Silva, Glenn Dranoff, Jeffrey A Porter, Keith Mansfield, Viviana Cremasco, Aviv Regev, Ramnik J Xavier, Daniel B Graham
Publikováno v:
PLoS Biology, Vol 20, Iss 1, p e3001532 (2022)
Chronic inflammation is often associated with the development of tissue fibrosis, but how mesenchymal cell responses dictate pathological fibrosis versus resolution and healing remains unclear. Defining stromal heterogeneity and identifying molecular
Externí odkaz:
https://doaj.org/article/56ff678867654cd1ac04c58c9f8ec4d5
Autor:
Daniel B. Graham, Jennifer G. Abelin, Daniel J. O’Connell, Kara L. Conway, Chengwei Luo, Moran Yassour, Guadalupe J. Jasso, Steven A. Carr, Mukund Varma, Caline G Matar, Eric M. Brown, Ariel Lefkovith, Ramnik J. Xavier
Identifying immunodominant T cell epitopes remains a significant challenge in the context of infectious disease, autoimmunity, and immuno-oncology. To address the challenge of antigen discovery, we developed a quantitative proteomic approach that ena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::425eeb80f638e12da3f6f708049591da
https://europepmc.org/articles/PMC6312190/
https://europepmc.org/articles/PMC6312190/
Autor:
Guadalupe J. Jasso, Daniel B. Graham, Gautam Goel, John G. Doench, Amanda Mok, Mukund Varma, Clary B. Clish, Steven A. Carr, Raivo Kolde, David E. Root, Aylwin Ng, Ramnik J. Xavier
Phagocyte microbiocidal mechanisms and inflammatory cytokine production are temporally coordinated, although their respective interdependencies remain incompletely understood. Here, we identify a nitric-oxide-mediated antioxidant response as a negati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63fdbc34baf48e884fcb9a39d07cac74
https://europepmc.org/articles/PMC6156773/
https://europepmc.org/articles/PMC6156773/
Endogenous dendritic cells from the tumor microenvironment support T-ALL growth via IGF1R activation
Autor:
Andrea N. Marcogliese, Hilary J. Selden, Xi Chen, Utpal P. Davé, Kim Cardenas, Guadalupe J. Jasso, Zicheng Hu, Jessica N. Lancaster, LiQi Li, Todd A. Triplett, Sadhana Balasubramanyam, Lauren I.R. Ehrlich, Kathy Chan, Paul E. Love
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Primary T-cell acute lymphoblastic leukemia (T-ALL) cells require stromal-derived signals to survive. Although many studies have identified cell-intrinsic alterations in signaling pathways that promote T-ALL growth, the identity of endogenous stromal
Autor:
Li LiQi, Sadhana Balasubramanyam, Zicheng Hu, Hilary J. Selden, Kim Cardenas, Todd A. Triplett, Paul E. Love, Jessica Jones, Guadalupe J. Jasso, Lauren I.E. Ehrlich
Publikováno v:
Clinical Cancer Research. 21:A02-A02
Though many cell-intrinsic genetic and genomic alterations contributing to tumorigenesis of T cell acute lymphoblastic leukemia/lymphoma (T-ALL) have been uncovered, the contributions of non-tumor cells and their associated signals in the tumor micro