Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Guadalupe Fernández‐Villullas"'
1
Akademický článek
Genome-Wide DNA Methylation in Early-Onset-Dementia Patients Brain Tissue and Lymphoblastoid Cell Lines
Autor: Oscar Ramos-Campoy, Aina Comas-Albertí, David Hervás, Sergi Borrego-Écija, Beatriz Bosch, Juan Sandoval, Laura Fort-Aznar, Fermín Moreno-Izco, Guadalupe Fernández-Villullas, Laura Molina-Porcel, Mircea Balasa, Albert Lladó, Raquel Sánchez-Valle, Anna Antonell
Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 10, p 5445 (2024)
Epigenetics, a potential underlying pathogenic mechanism of neurodegenerative diseases, has been in the scope of several studies performed so far. However, there is a gap in regard to analyzing different forms of early-onset dementia and the use of L
Externí odkaz: https://doaj.org/article/de7e140399df458ea0f0d4fc83440904
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2
Akademický článek
Early‐onset Alzheimer's disease shows a distinct neuropsychological profile and more aggressive trajectories of cognitive decline than late‐onset
Autor: Adrià Tort‐Merino, Neus Falgàs, Isabel E. Allen, Mircea Balasa, Jaume Olives, José Contador, Magdalena Castellví, Jordi Juncà‐Parella, Núria Guillén, Sergi Borrego‐Écija, Bea Bosch, Guadalupe Fernández‐Villullas, Oscar Ramos‐Campoy, Anna Antonell, Lorena Rami, Raquel Sánchez‐Valle, Albert Lladó
Publikováno v: Annals of Clinical and Translational Neurology, Vol 9, Iss 12, Pp 1962-1973 (2022)
Abstract Objectives Early‐ and late‐onset Alzheimer's disease (EOAD and LOAD) share the same neuropathological traits but show distinct cognitive features. We aimed to explore baseline and longitudinal outcomes of global and domain‐specific cog
Externí odkaz: https://doaj.org/article/abe403be0281408b803f9a1bb91e097a
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4
Akademický článek
Hippocampal atrophy has limited usefulness as a diagnostic biomarker on the early onset Alzheimer's disease patients: A comparison between visual and quantitative assessment
Autor: Neus Falgàs, Raquel Sánchez-Valle, Núria Bargalló, Mircea Balasa, Guadalupe Fernández-Villullas, Beatriz Bosch, Jaume Olives, Adrià Tort-Merino, Anna Antonell, Cristina Muñoz-García, María León, Oriol Grau, Magdalena Castellví, Nina Coll-Padrós, Lorena Rami, Alberto Redolfi, Albert Lladó
Publikováno v: NeuroImage: Clinical, Vol 23, Iss , Pp - (2019)
NIA-AA diagnostic criteria include volumetric or visual rating measures of hippocampal atrophy (HA) as a diagnostic biomarker of Alzheimer's disease (AD). We aimed to determine its utility as a diagnostic biomarker for early onset Alzheimer's disease
Externí odkaz: https://doaj.org/article/d33a4d3eeca449459df72bae85e101e3
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5
The APOE4 effect: structural brain differences in Alzheimer's disease according to the age at symptom onset
Autor: Gonzalo Forno, Jose Contador, Agnès Pérez‐Millan, Nuria Guillen, Neus Falgàs, Jordi Sarto, Adrià Tort‐Merino, Magdalena Castellví, Beatriz Bosch, Guadalupe Fernández‐Villullas, Mircea Balasa, Anna Antonell, Roser Sala‐ Llonch, Raquel Sanchez‐Valle, Michael Hornberger, Albert Lladó
Publikováno v: European Journal of Neurology. 30:597-605
How the APOE genotype can differentially affect cortical and subcortical memory structures in biomarker-confirmed early-onset (EOAD) and late-onset (LOAD) Alzheimer's disease (AD) was assessed.Eighty-seven cerebrospinal fluid (CSF) biomarker-confirme
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35bbf3e24a0e63a56178b766fb478cd0
https://doi.org/10.1111/ene.15657
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7
Sex differences in early-onset Alzheimer's disease
Autor: José Contador, Agnès Pérez‐Millan, Nuria Guillén, Jordi Sarto, Adrià Tort‐Merino, Mircea Balasa, Neus Falgàs, Magdalena Castellví, Sergi Borrego‐Écija, Jordi Juncà‐Parella, Beatriz Bosch, Guadalupe Fernández‐Villullas, Oscar Ramos‐Campoy, Anna Antonell, Nuria Bargalló, Raquel Sanchez‐Valle, Roser Sala‐Llonch, Albert Lladó
Publikováno v: European journal of neurologyREFERENCES. 29(12)
Sex is believed to drive heterogeneity in Alzheimer's disease (AD), although evidence in early-onset AD (EOAD;lt;65 years) is scarce.We included 62 EOAD patients and 44 healthy controls (HCs) with core AD cerebrospinal fluid (CSF) biomarkers, neurofi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::658701df0614eaeef7cf063759c26a58
https://pubmed.ncbi.nlm.nih.gov/36005384
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8
Contribution of CSF biomarkers to early‐onset Alzheimer's disease and frontotemporal dementia neuroimaging signatures
Autor: Sergi Borrego-Écija, Oscar Ramos-Campoy, Neus Falgàs, Mircea Balasa, Josep M. Augé, Albert Lladó, Henrik Zetterberg, Adrià Tort-Merino, Magdalena Castellví, Jaume Olives, Mariona Ruiz‐Peris, Raquel Sánchez-Valle, Guadalupe Fernández-Villullas, Núria Bargalló, Anna Antonell, Agnés Pérez‐Millan, Roser Sala-Llonch, Kaj Blennow
Publikováno v: Dipòsit Digital de la UB
Universidad de Barcelona
Human Brain Mapping
Prior studies have described distinct patterns of brain gray matter and white matter alterations in Alzheimer's disease (AD) and frontotemporal lobar degeneration (FTLD), as well as differences in their cerebrospinal fluid (CSF) biomarkers profiles.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbd87c52d8c1f0228a1628f9fa16c967
https://doi.org/10.1002/hbm.24925
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10
Baseline MRI atrophy predicts 2-year cognitive outcomes in early-onset Alzheimer's disease
Autor: José, Contador, Agnès, Pérez-Millan, Nuria, Guillen, Adrià, Tort-Merino, Mircea, Balasa, Neus, Falgàs, Jaume, Olives, Magdalena, Castellví, Sergi, Borrego-Écija, Beatriz, Bosch, Guadalupe, Fernández-Villullas, Oscar, Ramos-Campoy, Anna, Antonell, Nuria, Bargalló, Raquel, Sanchez-Valle, Roser, Sala-Llonch, Albert, Lladó
Publikováno v: Journal of neurology. 269(5)
MRI atrophy predicts cognitive status in AD. However, this relationship has not been investigated in early-onset AD (EOAD, 65 years) patients with a biomarker-based diagnosis.Forty eight EOAD (MMSE ≥ 15; A + T + N +) and forty two age-matched healt
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::904942bd11e4c7981fef42844ad65901
https://pubmed.ncbi.nlm.nih.gov/34665329
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