Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Guadalupe Dominguez‑Gomez"'
Autor:
Alejandro Schcolnik-Cabrera, Alma Chavez-Blanco, Guadalupe Dominguez-Gomez, Mandy Juarez, Ariana Vargas-Castillo, Rafael Isaac Ponce-Toledo, Donna Lai, Sheng Hua, Armando R. Tovar, Nimbe Torres, Delia Perez-Montiel, Jose Diaz-Chavez, Alfonso Duenas-Gonzalez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The malignant energetic demands are satisfied through glycolysis, glutaminolysis and de novo synthesis of fatty acids, while the host curses with a state of catabolism and systemic inflammation. The concurrent inhibition of both, tumor anabo
Externí odkaz:
https://doaj.org/article/f99339e0268a4075931c6a4545b04390
Autor:
Aurora Gonzalez-Fierro, Adriana Romo-Pérez, Alma Chávez-Blanco, Guadalupe Dominguez-Gomez, Alfonso Duenas-Gonzalez
Publikováno v:
Clinical Drug Investigation. 43:227-239
Autor:
Elisa García-Martínez, Leonardo S. Lino-Silva, Adriana Romo-Pérez, Alma Chavez-Blanco, Guadalupe Dominguez-Gomez, Lucia Taja-Chayeb, Horacio N Lopez-Basave, Alejandro E Padilla-Rosciano, Consuelo Diaz-Romero, Catalina Trejo-Becerril, Aurora González-Fierro, Alfonso Duenas-González
PurposeThe malignant metabolic phenotype characterized by high rates of glycolysis, glutaminolysis and de novo synthesis of fatty acids is also observed in gastric carcinoma. These alterations can be used as therapeutical opportunities with the use o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::806663b36bcbcf32b4f3ab4e8d75b4d2
https://doi.org/10.21203/rs.3.rs-1743405/v1
https://doi.org/10.21203/rs.3.rs-1743405/v1
Autor:
Elisa García-Martínez, Leonardo S. Lino-Silva, Adriana Romo-Pérez, Alma Chavez-Blanco, Guadalupe Dominguez-Gomez, Lucia Taja-Chayeb, Horacio N. Lopez-Basave, Alejandro E. Padilla Rosciano, Consuelo Diaz-Romero, Catalina Trejo-Becerril, Aurora Gonzalez-Fierro, Alfonso Duenas-Gonzalez
Publikováno v:
SSRN Electronic Journal.
Autor:
Alfonso Duenas-Gonzalez, Adriana Romo-Perez, Guadalupe Dominguez-Gomez, Alma Chavez-Blanco, Lucia Taja-Chayeb, Aurora Gonzalez-Fierro, Consuelo Diaz-Romero, Horacio Noe Lopez-Basave
Publikováno v:
Current cancer drug targets. 22(9)
Background: Worldwide, gastric cancer is ranked the fifth malignancy in incidence and the third malignancy in mortality. Gastric cancer causes an altered metabolism that can be therapeutically exploited. Objective: The objective of this study is to p
Autor:
Guadalupe Dominguez-Gomez, L Taja-Chayeb, Aurora Gonzalez-Fierro, Catalina Trejo-Becerril, S Vidal-Millán, Adriana Romo-Pérez, Alma Chavez-Blanco, Alfonso Dueñas-González, Enrique Pérez-Cárdenas
Publikováno v:
Clinics and research in hepatology and gastroenterology. 46(4)
It is estimated that up to 10% of gastric carcinomas show familial aggregation. In contrast, around 1-3 % (approximately 33,000 yearly) are genuinely hereditary. Hereditary diffuse gastric cancer (HDGC) is a rare malignancy characterized by autosomal
Autor:
Donna Lai, Alfonso Dueñas González, Alejandro Schcolnik‑Cabrera, Guadalupe Dominguez‑Gomez, Sheng Hua, Armando R. Tovar, Mandy Juarez, Alma Chavez‑Blanco, Jose Diaz‑Chavez
Publikováno v:
Oncol Lett
Cancer upregulates glycolysis, glutaminolysis and lipogenesis, and induces a catabolic state in patients. The concurrent inhibition of both tumor anabolism and host catabolism, and the energetic consequences of such an approach, have not previously b
Autor:
Marisol Ramírez‑Yautentzi, Alejandro Schcolnik‑Cabrera, Alma Chavez‑Blanco, Alfonso Dueñas González, Rocío Morales‑Bárcenas, Jose Diaz‑Chavez, Lucía Taja‑Chayeb, Guadalupe Dominguez‑Gomez
Publikováno v:
Oncology Letters
Lonidamine, 6-Diazo-5-oxo-L-norleucine (DON) and orlistat are well known inhibitors of glycolysis, glutaminolysis and of de novo fatty acid synthesis, respectively. Although their antitumor effects have been explored in detail, the potential inhibiti
Autor:
Berenice Prestegui Martel, Alma Delia Chávez-Blanco, Guadalupe Domínguez-Gómez, Alfonso Dueñas González, Patricia Gaona-Aguas, Raúl Flores-Mejía, Selma Alin Somilleda-Ventura, Octavio Rodríguez-Cortes, Rocío Morales-Bárcena, Alberto Martínez Muñoz, Cesar Miguel Mejia Barradas, Jessica Elena Mendieta Wejebe, José Correa Basurto
Publikováno v:
Molecules, Vol 29, Iss 15, p 3509 (2024)
In this work, we performed anti-proliferative assays for the compound N-(2-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA) on breast cancer (BC) cells (MCF-7, SKBR3, and triple-negative BC (TNBC) MDA-MB-231 cells) to explore its pharmacological mechani
Externí odkaz:
https://doaj.org/article/a948e4b9f6f941f78c57e492e1d76e31
Autor:
Guadalupe Dominguez‑Gomez, Alejandro Schcolnik‑Cabrera, Jose Diaz‑Chavez, Alfonso Dueñas González, Dominique Cortez‑Pedroza, Fredy Beltran‑Anaya, Aurora Gonzalez‑Fierro, Lucía Taja Chayeb, Alberto Cedro‑Tanda, Alfredo Hidalgo‑Miranda, Alma Chavez‑Blanco
Publikováno v:
Oncology reports. 42(3)
Ribavirin exhibits inhibitory effects on the epigenetic enzyme enhancer of zeste homolog 2 (EZH2), which participates in lymphomagenesis. Additionally, preclinical and clinical studies have demonstrated the anti‑lymphoma activity of this drug. To f