Zobrazeno 1 - 10
of 10
pro vyhledávání: '"GuHCl, guanidine hydrochloride"'
Autor:
Naomi Mihira, Misaki Sekiguchi, Kenichi Nagata, Takashi Saito, Toshio Ohshima, Kaori Sato, Hiroki Sasaguri, Takaomi C. Saido, Naoto Watamura, Ryo Fujioka
Publikováno v:
The Journal of Biological Chemistry
We previously developed single App knock-in mouse models of Alzheimer's disease (AD) harboring the Swedish and Beyreuther/Iberian mutations with or without the Arctic mutation (AppNL-G-F and AppNL-F mice, respectively). These models showed Aβ pathol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c901230fb3cfb1cf28cfd7fab0de79ae
https://doi.org/10.1016/j.jbc.2021.101004
https://doi.org/10.1016/j.jbc.2021.101004
Autor:
John R. Atack, Wei-Feng Xue, Louise C. Serpell, Ana Caroline Raulin, Youssra K. Al-Hilaly, John McGeehan, Lucas Kraft
Publikováno v:
Journal of Molecular Biology
Raulin, A-C, Kraft, L, Al-Hilaly, Y, Xue, W-F, McGeehan, J, Atack, J & Serpell, L C 2019, ' The molecular basis for Apolipoprotein E4 as the major risk factor for late onset Alzheimer's disease ', Journal of Molecular Biology, vol. 431, no. 12, pp. 2248-2265 . https://doi.org/10.1016/j.jmb.2019.04.019
Raulin, A-C, Kraft, L, Al-Hilaly, Y, Xue, W-F, McGeehan, J, Atack, J & Serpell, L C 2019, ' The molecular basis for Apolipoprotein E4 as the major risk factor for late onset Alzheimer's disease ', Journal of Molecular Biology, vol. 431, no. 12, pp. 2248-2265 . https://doi.org/10.1016/j.jmb.2019.04.019
Apolipoprotein E4 (ApoE4) is one of three (E2, E3 and E4) human isoforms of an α-helical, 299-amino-acid protein. Homozygosity for the ε4 allele is the major genetic risk factor for developing late-onset Alzheimer's disease (AD). ApoE2, ApoE3 and A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05a9d6a9f7dcb0650d86ec70dd141851
http://sro.sussex.ac.uk/id/eprint/83616/7/1-s2.0-S0022283619302268-main.pdf
http://sro.sussex.ac.uk/id/eprint/83616/7/1-s2.0-S0022283619302268-main.pdf
Autor:
Andras Lukacs, András Kengyel, Elek Telek, Henriett Halász, Kristof Karadi, Beáta Bugyi, Miklós Nyitrai, József Kardos, Zsuzsanna Fekete
Publikováno v:
The Journal of Biological Chemistry
The lesser-known unconventional myosin 16 protein is essential in proper neuronal functioning and has been implicated in cell cycle regulation. Its longer Myo16b isoform contains a C-terminal tail extension (Myo16Tail), which has been shown to play a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61ea193c50307e98951fb7f431981c6b
https://doi.org/10.1016/j.jbc.2021.100716
https://doi.org/10.1016/j.jbc.2021.100716
Publikováno v:
Journal of Molecular Biology
Repeat proteins are formed from units of 20–40 aa that stack together into quasi one-dimensional non-globular structures. This modular repetitive construction means that, unlike globular proteins, a repeat protein's equilibrium folding and thus the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::d5c41e13bfb955ec7037f0ccc89544ca
http://europepmc.org/articles/PMC4871810
http://europepmc.org/articles/PMC4871810
Autor:
Xu Shen, Shuying Peng, Jianhua Shen, Tao Sun, Liduo Yue, Fei Ye, Yuan Wang, Guo-wei Li, Hualiang Jiang, Jing Chen, Yiming Yang, Haibin Luo, Youhua Xie, Yi Du
Publikováno v:
Biophysical Chemistry
The major biochemical and thermodynamic features of nucelocapsid protein of SARS coronavirus (SARS_NP) were characterized by use of non-denatured gel electrophoresis, size-exclusion chromatographic and surface plasmon resonance (SPR) techniques. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29348ea93d8ad1e888a9a45c47373ee
http://europepmc.org/articles/PMC7116930
http://europepmc.org/articles/PMC7116930
Publikováno v:
Biochimie
Type III galactosemia results from reduced activity of the enzyme UDP-galactose 4′-epimerase. Five disease-associated alleles (G90E, V94M, D103G, N34S and L183P) and three artificial alleles (Y105C, N268D, and M284K) were tested for their ability t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337347e0300d78eaca08593005b28af5
https://pubmed.ncbi.nlm.nih.gov/21703329
https://pubmed.ncbi.nlm.nih.gov/21703329
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Autor:
Oehme D; The Ritchie Centre, Monash Institute of Medical Research, Monash University, Clayton, Victoria;, Ghosh P, Shimmon S, Wu J, McDonald C, Troupis JM, Goldschlager T, Rosenfeld JV, Jenkin G
Publikováno v:
Journal of neurosurgery. Spine [J Neurosurg Spine] 2014 Jun; Vol. 20 (6), pp. 657-69. Date of Electronic Publication: 2014 Apr 04.