Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Gu Zhan"'
Publikováno v:
Zeitschrift für Kristallographie - New Crystal Structures, Vol 239, Iss 5, Pp 865-867 (2024)
C24H25FN4O10, triclinic, P1̄ (no. 2), a = 7.7217(3) Å, b = 9.9451(4) Å, c = 15.9291(6) Å, α = 101.741(1)∘, β = 98.762(1)∘, γ = 96.148(1)∘, V = 1171.56(8) Å3, Z = 2, Rgt(F) = 0.0389, wRref(F2) = 0.1162, T = 170 K.
Externí odkaz:
https://doaj.org/article/f1f2ae7d976a4f9984b95d81067b9c42
Publikováno v:
Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)
Abstract Heteroaromatic N‐oxides, renowned for their highly polar N─O bond and robust structure, exhibit significant bioactivities and have played a pivotal role in various drug development projects since the discovery of Minoxidil. Moreover, het
Externí odkaz:
https://doaj.org/article/b7c626486f754ce4b634582b60e09e2d
Autor:
Fu Peng, Minru Liao, Wenke Jin, Wei Liu, Zixiang Li, Zhichao Fan, Ling Zou, Siwei Chen, Lingjuan Zhu, Qian Zhao, Gu Zhan, Liang Ouyang, Cheng Peng, Bo Han, Jin Zhang, Leilei Fu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-17 (2024)
Abstract Sirtuin 3 (SIRT3) is well known as a conserved nicotinamide adenine dinucleotide+ (NAD+)-dependent deacetylase located in the mitochondria that may regulate oxidative stress, catabolism and ATP production. Accumulating evidence has recently
Externí odkaz:
https://doaj.org/article/0c9da444ccf442e3b3e6e2e182b75a0c
Publikováno v:
Communications Chemistry, Vol 6, Iss 1, Pp 1-13 (2023)
Abstract Significant progress has been made in asymmetric synthesis through the use of transition metal catalysts combined with Lewis bases. However, the use of a dual catalytic system involving 4-aminopyridine and transition metal has received littl
Externí odkaz:
https://doaj.org/article/acdbd68d9ebd47ef9e02037e56cb9460
Publikováno v:
Frontiers in Chemistry, Vol 12 (2024)
Externí odkaz:
https://doaj.org/article/bf48ce9e6e484d99af7e77ab0f4b1e0a
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-49 (2022)
Abstract Regulated cell death (RCD) is a critical and active process that is controlled by specific signal transduction pathways and can be regulated by genetic signals or drug interventions. Meanwhile, RCD is closely related to the occurrence and th
Externí odkaz:
https://doaj.org/article/2effabe59bb24f469761afe92af68337
Autor:
Meng-Lan Luo, Qian Zhao, Xiang-Hong He, Xin Xie, Hong-Ping Zhu, Feng-Ming You, Cheng Peng, Gu Zhan, Wei Huang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114574- (2023)
Allosteric modulation is a direct and effective method for regulating the function of biological macromolecules, which play vital roles in various cellular activities. Unlike orthosteric modulators, allosteric modulators bind to sites distant from th
Externí odkaz:
https://doaj.org/article/2f425f18ba55454e8fce847445fae2cb
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Indole alkaloids are widely distributed in nature and have been particularly studied because of their diverse biological activities, such as anti-inflammatory, anti-tumor, anti-bacterial, and anti-oxidant activities. Many kinds of indole alkaloids ha
Externí odkaz:
https://doaj.org/article/a9f2fb299945449fbbde0625ab52f5f0
Publikováno v:
Journal of Hematology & Oncology, Vol 15, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/d4d6a7b648e74573837ec4d793d393b0
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 309-313 (2016)
7-Azaisatin and 7-azaoxindole skeletons are valuable building blocks in diverse biologically active substances. Here 7-azaisatins turned out to be more efficient electrophiles than the analogous isatins in the enantioselective Morita–Baylis–Hillm
Externí odkaz:
https://doaj.org/article/be7b037f8f3c48438229222206ab5dda