Role of Sodium-Dependent Vitamin C Transporter-2 and Ascorbate in Regulating the Hypoxic Pathway in Cultured Glioblastoma Cells.

Autor: Burgess ER; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand.; Department of Immunobiochemistry, Mannheim Institute for Innate Immunology (MI3), Heidelberg University, Medical Faculty Mannheim, Mannheim, Germany., Praditi C; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand.; Mātai Hāora, Centre for Redox Biology and Medicine, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand., Phillips E; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand., Vissers MCM; Mātai Hāora, Centre for Redox Biology and Medicine, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand., Robinson BA; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand.; Canterbury Regional Cancer and Haematology Service, Te Whatu Ora, Waitaha/Canterbury, Christchurch, New Zealand., Dachs GU; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand., Wiggins GAR; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand.

Publikováno v: Journal of cellular biochemistry [J Cell Biochem] 2024 Oct 09, pp. e30658. Date of Electronic Publication: 2024 Oct 09.

Ascorbate Uptake and Retention by Breast Cancer Cell Lines and the Intracellular Distribution of Sodium-Dependent Vitamin C Transporter 2.

Autor: Praditi C; Mātai Hāora-Centre for Redox Biology and Medicine, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch 8011, New Zealand., Bozonet SM; Mātai Hāora-Centre for Redox Biology and Medicine, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch 8011, New Zealand., Dachs GU; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch 8011, New Zealand., Vissers MCM; Mātai Hāora-Centre for Redox Biology and Medicine, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch 8011, New Zealand.

Publikováno v: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2023 Oct 30; Vol. 12 (11). Date of Electronic Publication: 2023 Oct 30.

Ascorbate content of clinical glioma tissues is related to tumour grade and to global levels of 5-hydroxymethyl cytosine.

Autor: Crake RLI; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand.; Metastasis Research Laboratory, GIGA-Cancer, University of Liège, Liege, Belgium., Burgess ER; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand., Wiggins GAR; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand., Magon NJ; Centre for Free Radical Research, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand., Das AB; Centre for Free Radical Research, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand.; Peter MacCallum Cancer Centre, 305 Grattan St, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Parkville, VIC, Australia., Vissers MCM; Centre for Free Radical Research, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand., Morrin HR; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand.; Cancer Society Tissue Bank, University of Otago Christchurch, Christchurch, New Zealand., Royds JA; Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand., Slatter TL; Department of Pathology, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand., Robinson BA; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand.; Canterbury Regional Cancer and Haematology Service, Canterbury District Health Board, Christchurch, New Zealand.; Department of Medicine, University of Otago Christchurch, Christchurch, New Zealand., Phillips E; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand., Dachs GU; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago Christchurch, Christchurch, New Zealand. gabi.dachs@otago.ac.nz.

Publikováno v: Scientific reports [Sci Rep] 2022 Sep 01; Vol. 12 (1), pp. 14845. Date of Electronic Publication: 2022 Sep 01.

Restoring Tumour Selectivity of the Bioreductive Prodrug PR-104 by Developing an Analogue Resistant to Aerobic Metabolism by Human Aldo-Keto Reductase 1C3.

Autor: Abbattista MR; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand., Ashoorzadeh A; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand., Guise CP; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand., Mowday AM; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand., Mittra R; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand., Silva S; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand., Hicks KO; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand., Bull MR; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand., Jackson-Patel V; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand., Lin X; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand., Prosser GA; School of Biological Sciences, Victoria University of Wellington, Wellington 6011, New Zealand.; School of Life Sciences, University of Dundee, Dundee DD1 5EH, UK., Lambie NK; Department of Anatomical Pathology, Canterbury Health Laboratories, Christchurch 8140, New Zealand., Dachs GU; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand.; Department of Pathology and Biomedical Science, University of Otago, Christchurch 8140, New Zealand., Ackerley DF; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand.; School of Biological Sciences, Victoria University of Wellington, Wellington 6011, New Zealand., Smaill JB; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand., Patterson AV; Auckland Cancer Society Research Centre, School of Medical Sciences, The University of Auckland, Auckland 1142, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, Auckland 1142, New Zealand.

Publikováno v: Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2021 Nov 26; Vol. 14 (12). Date of Electronic Publication: 2021 Nov 26.

Effect of immune modulation on the skeletal muscle mitochondrial exercise response: An exploratory study in mice with cancer.

Autor: Buss LA; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand., Hock B; Hematology Research Group, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand., Merry TL; Discipline of Nutrition, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, University of Auckland, Auckland, New Zealand., Ang AD; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand., Robinson BA; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand.; Canterbury Regional Cancer and Hematology Service, Canterbury District Health Board, Christchurch, New Zealand., Currie MJ; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand., Dachs GU; Mackenzie Cancer Research Group, Department of Pathology and Biomedical Science, University of Otago, Christchurch, New Zealand.

Publikováno v: PloS one [PLoS One] 2021 Oct 19; Vol. 16 (10), pp. e0258831. Date of Electronic Publication: 2021 Oct 19 (Print Publication: 2021).