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Cardiac digital twins (CDTs) of human cardiac electrophysiology (EP) are digital replicas of patient hearts that match like-for-like clinical observations. The electrocardiogram (ECG), as the most prevalent non-invasive observation of cardiac electro
Externí odkaz:
http://arxiv.org/abs/2407.17146
Autor:
Arnold, Robert, Prassl, Anton J., Neic, Aurel, Thaler, Franz, Augustin, Christoph M., Gsell, Matthias A. F., Gillette, Karli, Manninger, Martin, Scherr, Daniel, Plank, Gernot
Background and Objective: Data from electro-anatomical mapping (EAM) systems are playing an increasingly important role in computational modeling studies for the patient-specific calibration of digital twin models. However, data exported from commerc
Externí odkaz:
http://arxiv.org/abs/2403.10394
Late gadolinium enhanced (LGE) magnetic resonance (MR) imaging is widely established to assess the viability of myocardial tissue of patients after acute myocardial infarction (MI). We propose the Cascading Refinement CNN (CaRe-CNN), which is a fully
Externí odkaz:
http://arxiv.org/abs/2312.11315
Autor:
K. Ahuja, M. Vandenabeele, F. Nami, E. Lefevere, J. Van hoecke, S. Bergmans, M. Claes, T. Vervliet, K. Neyrinck, T. Burg, D. De Herdt, P. Bhaskar, Y. Zhu, Z. J. Looser, J. Loncke, W. Gsell, M. Plaas, P. Agostinis, J. V. Swinnen, L. Van Den Bosch, G. Bultynck, A. S. Saab, E. Wolfs, Y. C. Chai, U. Himmelreich, C. Verfaillie, L. Moons, L. De Groef
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-23 (2024)
Abstract Wolfram syndrome (WS) is a rare childhood disease characterized by diabetes mellitus, diabetes insipidus, blindness, deafness, neurodegeneration and eventually early death, due to autosomal recessive mutations in the WFS1 (and WFS2) gene. Wh
Externí odkaz:
https://doaj.org/article/1fc5ac8a195045e784ceddeab1da8565
Hardening cyber physical assets is both crucial and labor-intensive. Recently, Machine Learning (ML) in general and Reinforcement Learning RL) more specifically has shown great promise to automate tasks that otherwise would require significant human
Externí odkaz:
http://arxiv.org/abs/2304.11052
Autor:
Amy Clarke, Julia Skerjanz, Mathias A. F. Gsell, Patrick Wiedner, Hazel Erkan-Candag, Klaus Groschner, Thomas Stockner, Oleksandra Tiapko
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The transient receptor potential canonical type 3 (TRPC3) channel plays a pivotal role in regulating neuronal excitability in the brain via its constitutive activity. The channel is intricately regulated by lipids and has previously been dem
Externí odkaz:
https://doaj.org/article/de6a853f0fa045d0a376f178fdcb572b
Autor:
Gillette, Karli, Gsell, Matthias A. F., Nagel, Claudia, Bender, Jule, Winkler, Bejamin, Williams, Steven E., Bär, Markus, Schäffter, Tobias, Dössel, Olaf, Plank, Gernot, Loewe, Axel
Mechanistic cardiac electrophysiology models allow for personalized simulations of the electrical activity in the heart and the ensuing electrocardiogram (ECG) on the body surface. As such, synthetic signals possess known ground truth labels of the u
Externí odkaz:
http://arxiv.org/abs/2211.15997
Autor:
Ismay A. E. deBeijer, Eline Bouwman, Renée L. Mulder, Philippa Steensma, Morven C. Brown, Vera Araújo‐Soares, Magdalena Balcerek, Edit Bardi, Jeanette Falck Winther, Line Elmerdahl Frederiksen, Marloes vanGorp, Sara Oberti, Rebecca J. vanKalsbeek, Tomas Kepak, Katerina Kepakova, Hannah Gsell, Anita Kienesberger, Raphaële vanLitsenburg, Luzius Mader, Gisela Michel, Monica Muraca, Selina R. van denOever, Helena J. H. van derPal, Katharina Roser, Roderick Skinner, Iridi Stolman, Anne Uyttebroeck, Leontien C. M. Kremer, Jacqueline Loonen, Elvira C. vanDalen, Saskia M. F. Pluijm, the PanCareFollowUp Consortium
Publikováno v:
Cancer Medicine, Vol 13, Iss 12, Pp n/a-n/a (2024)
Abstract Background Healthy behaviors are paramount in preventing long‐term adverse health outcomes in childhood, adolescent, and young adult (CAYA) cancer survivors. We systematically reviewed and synthesized existing literature on barriers, facil
Externí odkaz:
https://doaj.org/article/b953b9af67da49ee88e9ca2cdbcdc8e0
Autor:
Selina R. van den Oever, Tessa Fuchs, Gill A. Levitt, Riccardo Haupt, Renée L. Mulder, Ana Amariutei, Edit Bardi, Tom Becker, Morven Brown, Hannah Gsell, Jaap den Hartogh, Samira Essiaf, Monica Muraca, Emma Potter, Carina Schneider, Elaine Sugden, Zuzana Tomášiková, Herma Vermeulen, Leontien C.M. Kremer, Roderick Skinner, Helena J.H. van der Pal
Publikováno v:
EJC Paediatric Oncology, Vol 3, Iss , Pp 100165- (2024)
Background: Having sufficient knowledge of cancer diagnosis, treatment and late effects in survivors of childhood, adolescent, and young adult (CAYA) cancer is important for effective self-management and optimising health outcomes. Therefore, in coll
Externí odkaz:
https://doaj.org/article/3732033e0e034e64a6b4a81507279590
Autor:
Liesa J. Weiler‐Wichtl, Carina Schneider, Hannah Gsell, Anna‐Maria Maletzky, Anita Kienesberger, Claas Röhl, Albina Bocolli, Johannes Gojo, Rita Hansl, Anna Zettl, Maximilian Hopfgartner, Ulrike Leiss
Publikováno v:
Cancer Reports, Vol 7, Iss 5, Pp n/a-n/a (2024)
Abstract Background Patient and public involvement and engagement (PPIE) in healthcare research is crucial for effectively addressing patients' needs and setting appropriate research priorities. However, there is a lack of awareness and adequate meth
Externí odkaz:
https://doaj.org/article/8b0bf19689a94ca39a038a3ad49d7787