Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Grzegorz Wȩgrzyn"'
Autor:
Karolina Wiśniewska, Lidia Gaffke, Magdalena Żabińska, Grzegorz Węgrzyn, Karolina Pierzynowska
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 3, Pp 2678-2700 (2024)
Mucopolysaccharidoses (MPS) are a group of diseases caused by mutations in genes encoding lysosomal enzymes that catalyze reactions of glycosaminoglycan (GAG) degradation. As a result, GAGs accumulate in lysosomes, impairing the proper functioning of
Externí odkaz:
https://doaj.org/article/472ea883eaf540f3a8f99f9256047e04
Autor:
Magdalena Podlacha, Lidia Gaffke, Łukasz Grabowski, Jagoda Mantej, Michał Grabski, Małgorzata Pierzchalska, Karolina Pierzynowska, Grzegorz Węgrzyn, Alicja Węgrzyn
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract One of the hopes for overcoming the antibiotic resistance crisis is the use of bacteriophages to combat bacterial infections, the so-called phage therapy. This therapeutic approach is generally believed to be safe for humans and animals as p
Externí odkaz:
https://doaj.org/article/df9c80bb398e4f7098d62910ccb6774c
Autor:
Karolina Wiśniewska, Jakub Wolski, Magdalena Żabińska, Aneta Szulc, Lidia Gaffke, Karolina Pierzynowska, Grzegorz Węgrzyn
Publikováno v:
Diagnostics, Vol 14, Iss 16, p 1734 (2024)
Mucopolysaccharidoses (MPS) comprise a group of 12 metabolic disorders where defects in specific enzyme activities lead to the accumulation of glycosaminoglycans (GAGs) within lysosomes. This classification expands to 13 when considering MPS IIIE. Th
Externí odkaz:
https://doaj.org/article/c7db7486ac5c48ea955d6d2002499884
Autor:
Michał Grabski, Jan Gawor, Marta Cegłowska, Robert Gromadka, Hanna Mazur-Marzec, Grzegorz Węgrzyn
Publikováno v:
Microorganisms, Vol 12, Iss 8, p 1628 (2024)
Compounds derived from natural sources pave the way for novel drug development. Cyanobacteria is an ubiquitous phylum found in various habitats. The fitness of those microorganisms, within different biotopes, is partially dependent on secondary metab
Externí odkaz:
https://doaj.org/article/a06a32d3a21c4024927bfa86fb7c95dc
Autor:
Krzysztof Sitko, Sarolta Kárpáti, Grzegorz Węgrzyn, Grzegorz Mincewicz, Magdalena Trzeciak, Michael Kasperkiewicz, Stefan Tukaj
Publikováno v:
Frontiers in Medicine, Vol 10 (2024)
Heat shock protein 90 alpha (Hsp90α) is one of the key intra- and extracellular chaperones responsible for the biological activity of various signaling molecules that are involved in (auto)immune-mediated inflammatory diseases. Recent epidemiologic
Externí odkaz:
https://doaj.org/article/9fc912abf4204c8ab6f0d0a8963215aa
Autor:
Aneta Szulc, Karolina Wiśniewska, Magdalena Żabińska, Lidia Gaffke, Maria Szota, Zuzanna Olendzka, Grzegorz Węgrzyn, Karolina Pierzynowska
Publikováno v:
Foods, Vol 13, Iss 12, p 1931 (2024)
Over the past decades, there has been a significant increase in the burden of neurological diseases, including neurodegenerative disorders, on a global scale. This is linked to a widespread demographic trend in which developed societies are aging, le
Externí odkaz:
https://doaj.org/article/9f92d664106c44f98f1b70cbd3ecee1f
Autor:
Łukasz Grabowski, Karolina Pierzynowska, Katarzyna Kosznik-Kwaśnicka, Małgorzata Stasiłojć, Grażyna Jerzemowska, Alicja Węgrzyn, Grzegorz Węgrzyn, Magdalena Podlacha
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe problem of antibiotic resistance is a global one, involving many industries and entailing huge financial outlays. Therefore, the search for alternative methods to combat drug-resistant bacteria has a priority status. Great potential i
Externí odkaz:
https://doaj.org/article/c0dd1f53083f43f5be1656282ed525f4
Autor:
Florian Turbant, Emeline Esnouf, Francois Rosaz, Frank Wien, Grzegorz Węgrzyn, Hugo Chauvet, Véronique Arluison
Publikováno v:
Microorganisms, Vol 12, Iss 1, p 53 (2023)
Due to their two-cell membranes, Gram-negative bacteria are particularly resistant to antibiotics. Recent investigations aimed at exploring new target proteins involved in Gram-negative bacteria adaptation helped to identify environmental changes enc
Externí odkaz:
https://doaj.org/article/38c5a37af48a4494a832daa981cefd94
Autor:
Estera Rintz, Takashi Higuchi, Hiroshi Kobayashi, Deni S. Galileo, Grzegorz Wegrzyn, Shunji Tomatsu
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 24, Iss , Pp 71-87 (2022)
More than 50 lysosomal storage diseases (LSDs) are associated with lysosomal dysfunctions with the frequency of 1:5,000 live births. As a result of missing enzyme activity, the lysosome dysfunction accumulates undegraded or partially degraded molecul
Externí odkaz:
https://doaj.org/article/c83e54ba5bdb496cb03c6ad380a4ec53
Publikováno v:
BMC Genomics, Vol 23, Iss 1, Pp 1-12 (2022)
Abstract Background Enterohemorrhagic Escherichia coli (EHEC) is an emerging health challenge worldwide and outbreaks caused by this pathogen poses a serious public health concern. Shiga toxin (Stx) is the major virulence factor of EHEC, and the stx
Externí odkaz:
https://doaj.org/article/c0b0b6de781d40739230481519baff37