Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Grzegorz Rempala"'
Autor:
Anna Cebula, Michal Kuczma, Edyta Szurek, Maciej Pietrzak, Natasha Savage, Wessam R. Elhefnawy, Grzegorz Rempala, Piotr Kraj, Leszek Ignatowicz
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Autoreactive T cells are normally eliminated during their maturation in the thymus, but an unknown number of autoreactive CD4+ T cells escape to the periphery. Here the authors show, by comparing the T cell receptors of mice sufficient or deficient i
Externí odkaz:
https://doaj.org/article/f0ecadad87d6496c8f838eae6f2b9404
Autor:
Lauren M. Browning, Caroline Miller, Michal Kuczma, Maciej Pietrzak, Yu Jing, Grzegorz Rempala, Pawel Muranski, Leszek Ignatowicz, Piotr Kraj
Publikováno v:
Cell Reports, Vol 33, Iss 1, Pp 108219- (2020)
Summary: Bone morphogenic proteins (BMPs) are members of the transforming growth factor β (TGF-β) cytokine family promoting differentiation, homeostasis, and self-renewal of multiple tissues. We show that signaling through the bone morphogenic prot
Externí odkaz:
https://doaj.org/article/667fc846294b4f0a8093f179d49af5a6
Autor:
Lukasz Wojciech, Edyta Szurek, Michal Kuczma, Anna Cebula, Wessam R. Elhefnawy, Maciej Pietrzak, Grzegorz Rempala, Leszek Ignatowicz
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract In the gut, various subsets of intraepithelial T cells (IELs) respond to self or non-self-antigens derived from the body, diet, commensal and pathogenic microbiota. Dominant subset of IELs in the small intestine are TCRαβCD8αα+ cells, wh
Externí odkaz:
https://doaj.org/article/17fae1688ad846f5801bedc8c82b0475
Autor:
Roshan Mascarenhas, Maciej Pietrzak, Ryan M Smith, Amy Webb, Danxin Wang, Audrey C Papp, Julia K Pinsonneault, Michal Seweryn, Grzegorz Rempala, Wolfgang Sadee
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136798 (2015)
mRNA translation into proteins is highly regulated, but the role of mRNA isoforms, noncoding RNAs (ncRNAs), and genetic variants remains poorly understood. mRNA levels on polysomes have been shown to correlate well with expressed protein levels, poin
Externí odkaz:
https://doaj.org/article/034eadc90dc14c379ab2f79d10520787
Autor:
Edyta Szurek, Anna Cebula, Lukasz Wojciech, Maciej Pietrzak, Grzegorz Rempala, Pawel Kisielow, Leszek Ignatowicz
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141161 (2015)
Helios transcription factor and semaphorin receptor Nrp-1 were originally described as constitutively expressed at high levels on CD4+Foxp3+ T regulatory cells of intrathymic origin (tTregs). On the other hand, CD4+Foxp3+ Tregs generated in the perip
Externí odkaz:
https://doaj.org/article/994a36e571b541ec8e496972d802fd2e
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e22585 (2011)
Ribosomal deficits are documented in mild cognitive impairment (MCI), which often represents an early stage Alzheimer's disease (AD), as well as in advanced AD. The nucleolar rRNA genes (rDNA), transcription of which is critical for ribosomal biogene
Externí odkaz:
https://doaj.org/article/26c78544896646b08091bf963dea16d5
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2194
Survival analysis is tremendously powerful, and is a popular methodology for analyzing time to event models in bioinformatics. Furthermore, several of its extensions can simultaneously perform variable selection in conjunction with model estimation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8da03158259e635220aa1d731378052e
https://pubmed.ncbi.nlm.nih.gov/32926363
https://pubmed.ncbi.nlm.nih.gov/32926363
Autor:
Lauren M, Browning, Caroline, Miller, Michal, Kuczma, Maciej, Pietrzak, Yu, Jing, Grzegorz, Rempala, Pawel, Muranski, Leszek, Ignatowicz, Piotr, Kraj
Publikováno v:
Cell Rep
Bone morphogenic proteins (BMPs) are members of the transforming growth factor β (TGF-β) cytokine family promoting differentiation, homeostasis, and self-renewal of multiple tissues. We show that signaling through the bone morphogenic protein recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f783c69f62c09443b7fa1b079204c080
https://pubmed.ncbi.nlm.nih.gov/33027660
https://pubmed.ncbi.nlm.nih.gov/33027660
Autor:
Anna, Cebula, Michal, Kuczma, Edyta, Szurek, Maciej, Pietrzak, Natasha, Savage, Wessam R, Elhefnawy, Grzegorz, Rempala, Piotr, Kraj, Leszek, Ignatowicz
Publikováno v:
Nature Communications
Thymic central tolerance eliminates most immature T cells with autoreactive T cell receptors (TCR) that recognize self MHC/peptide complexes. Regardless, an unknown number of autoreactive CD4+Foxp3− T cells escape negative selection and in the peri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a5f551a863bafb72cfa641dc5926e693
https://pubmed.ncbi.nlm.nih.gov/31653839
https://pubmed.ncbi.nlm.nih.gov/31653839
Autor:
Lauren M, Browning, Maciej, Pietrzak, Michal, Kuczma, Colin P, Simms, Agnieszka, Kurczewska, Justin M, Refugia, Dustin J, Lowery, Grzegorz, Rempala, Dmitriy, Gutkin, Leszek, Ignatowicz, Pawel, Muranski, Piotr, Kraj
Publikováno v:
Sci Signal
The cytokines of the transforming growth factor–β (TGF-β) family promote the growth and differentiation of multiple tissues but the role of only the founding member, TGF-β, in regulating the immune responses has been extensively studied. TGF-β
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5fe66c1ff3fb66a78940b41eb01b0bf7
https://pubmed.ncbi.nlm.nih.gov/30154100
https://pubmed.ncbi.nlm.nih.gov/30154100