Revisiting the conformational state of albumin conjugated to gold nanoclusters: A self-assembly pathway to giant superstructures unraveled.

Autor: Michał Kluz, Hanna Nieznańska, Robert Dec, Igor Dzięcielewski, Bartosz Niżyński, Grzegorz Ścibisz, Wojciech Puławski, Grzegorz Staszczak, Ewelina Klein, Julita Smalc-Koziorowska, Wojciech Dzwolak

Publikováno v: PLoS ONE, Vol 14, Iss 6, p e0218975 (2019)

Bovine serum albumin (BSA) is often employed as a proteinaceous component for synthesis of luminescent protein-stabilized gold nanoclusters (AuNC): intriguing systems with many potential applications. Typically, the formation of BSA-AuNC conjugate oc

Externí odkaz: https://doaj.org/article/cc0ade19bd0242b4b42b65d915dd99d3

Reversible Freeze-Induced β-Sheet-to-Disorder Transition in Aggregated Homopolypeptide System

Autor: Mateusz Fortunka, Marcin Guza, Matylda Wacławska, Robert Dec, Wojciech Puławski, Grzegorz Ścibisz, Wojciech Dzwolak

Publikováno v: The journal of physical chemistry. B. 123(43)

Conformational transitions involving aggregated proteins or peptides are of paramount biomedical and biotechnological importance. Here, we report an unusual freeze-induced structural reorganization within a β-sheet-rich ionic coaggregate of poly(l-l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b0bcd887332d76592b312b647a2a2ec
https://pubmed.ncbi.nlm.nih.gov/31584823

β

Autor: Sylwia, Berbeć, Robert, Dec, Dmitry, Molodenskiy, Beata, Wielgus-Kutrowska, Christian, Johannessen, Agnieszka, Hernik-Magoń, Fernando, Tobias, Agnieszka, Bzowska, Grzegorz, Ścibisz, Timothy A, Keiderling, Dmitri, Svergun, Wojciech, Dzwolak

Publikováno v: The journal of physical chemistry. B. 122(50)

Replacing water with dimethyl sulfoxide (DMSO) completely reshapes the free-energy landscapes of solvated proteins. In DMSO, a powerful hydrogen-bond (HB) acceptor, formation of HBs between backbone NH groups and solvent is favored over HBs involving

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3548feae4abd0bd9f1fc1ccc33be213f
https://pubmed.ncbi.nlm.nih.gov/30427196

β 2 -Type Amyloidlike Fibrils of Poly- l -glutamic Acid Convert into Long, Highly Ordered Helices upon Dissolution in Dimethyl Sulfoxide

Autor: Agnieszka Hernik-Magoń, Sylwia Berbeć, Dmitri I. Svergun, Christian Johannessen, Robert Dec, Agnieszka Bzowska, Fernando Tobias, Timothy A. Keiderling, Wojciech Dzwolak, Grzegorz Ścibisz, Beata Wielgus-Kutrowska, Dmitry S. Molodenskiy

Publikováno v: The Journal of Physical Chemistry B
The journal of physical chemistry : B : condensed matter, materials, surfaces, interfaces and biophysical

Replacing water with dimethyl sulfoxide (DMSO) completely reshapes the free-energy landscapes of solvated proteins. In DMSO, a powerful hydrogen-bond (HB) acceptor, formation of HBs between backbone NH groups and solvent is favored over HBs involving

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fecf67c6095cac0ee161b6f55c166f7d