Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Grzegorz, Kazek"'
Autor:
Marta Szwajca, Grzegorz Kazek, Natalia Śmierciak, Józef Mizera, Lucyna Pomierny-Chamiolo, Krzysztof Szwajca, Beata Biesaga, Maciej Pilecki
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
AimSchizophrenia involves complex interactions between biological and environmental factors, including childhood trauma, cognitive impairments, and premorbid adjustment. Predicting its severity and progression remains challenging. Biomarkers like gli
Externí odkaz:
https://doaj.org/article/3b76d4beeb6d481db4640737300da143
Autor:
Grzegorz Kazek, Monika Głuch-Lutwin, Barbara Mordyl, Elżbieta Menaszek, Monika Kubacka, Anna Jurowska, Dariusz Cież, Bartosz Trzewik, Janusz Szklarzewicz, Monika A. Papież
Publikováno v:
Pharmaceuticals, Vol 17, Iss 2, p 229 (2024)
In the text, the synthesis and characteristics of the novel ONS-type vanadium (V) complexes with thioanilide derivatives of amino acids are described. They showed the inhibition of human protein tyrosine phosphatases (PTP1B, LAR, SHP1, and SHP2) in t
Externí odkaz:
https://doaj.org/article/12c73147d33048dbb272b70c13fc6acf
Autor:
Natalia Śmierciak, Wirginia Krzyściak, Marta Szwajca, Grzegorz Kazek, Katarzyna Urbanek, Amira Bryll, Maciej Pilecki
Publikováno v:
Psychiatria i Psychologia Kliniczna, Vol 18, Iss 4, Pp 388-398 (2018)
Schizofrenia należy do coraz poważniejszych problemów medycznych i społecznych. Pomimo postępu w farmakoterapii i innych formach terapii psychoz pozostaje ona zaburzeniem o chronicznym i degradującym przebiegu. Kilka dekad badań nad jej uwar
Externí odkaz:
https://doaj.org/article/546960004cfd4f88bd9c259171bbf75c
Autor:
Grzegorz Kazek, Monika Głuch-Lutwin, Barbara Mordyl, Monika Kubacka, Anna Jurowska, Dariusz Cież, Bartosz Trzewik, Janusz Szklarzewicz, Monika A. Papież
In the text, the synthesis and characteristics of the novel ONS-type vanadium(V) complexes with thioanilide derivatives of amino acids are described. They have shown inhibition of human protein tyrosine phosphatases (PTP1B, LAR, SHP1 and SHP2) in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b333397af47ec3fc0767c1c3afd442da
https://doi.org/10.20944/preprints202304.0713.v2
https://doi.org/10.20944/preprints202304.0713.v2
Autor:
Kinga Sałaciak, Natalia Malikowska-Racia, Klaudia Lustyk, Agata Siwek, Monika Głuch-Lutwin, Grzegorz Kazek, Justyna Popiół, Jacek Sapa, Henryk Marona, Dorota Żelaszczyk, Karolina Pytka
Publikováno v:
Pharmaceuticals, Vol 14, Iss 8, p 744 (2021)
The increasing number of patients reporting depressive symptoms requires the design of new antidepressants with higher efficacy and limited side effects. As our previous research showed, 2-methoxyphenylpiperazine derivatives are promising candidates
Externí odkaz:
https://doaj.org/article/ffe77bfce64941849e5dbfd0d2020f70
Autor:
Grzegorz Kazek, Monika Głuch-Lutwin, Barbara Mordyl, Monika Kubacka, Anna Jurowska, Dariusz Cież, Bartosz Trzewik, Janusz Szklarzewicz, Monika A. Papież
The synthesis and characteristics of the novel ONS-type vanadium(V) complexes with thioanilidine derivatives of aminoacids have been described. They showed inhibition of human protein tyrosine phosphatases (PTP1B, LAR, SHP1 and SHP2) in the submicrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a2bc2c5fb7c6e1d7ddfa5f95b8d340ca
https://doi.org/10.20944/preprints202304.0713.v1
https://doi.org/10.20944/preprints202304.0713.v1
Autor:
Maciej Hodorowicz, Elżbieta Menaszek, Barbara Mordyl, Janusz Szklarzewicz, Jacek Sapa, Anna Jurowska, Grzegorz Kazek
Publikováno v:
Transition Metal Chemistry. 46:201-217
Twenty-four oxidovanadium(IV,V) complexes with tridentate Schiff base ligands based on 5-nitrosalicylaldehyde, 5-methoxysalicylaldehyde, or 5-sulfosalicylaldehyde and respective hydrazide were isolated, and characterized using physicochemical and spe
Autor:
Karolina Pytka, Leszek Nowiński, Marek Bednarski, Małgorzata Szafarz, Emma J. Mitchell, Henryk Marona, Kinga Sałaciak, Monika Głuch-Lutwin, Agata Siwek, Magdalena Jastrzębska-Więsek, Anna Partyka, Marcin Kołaczkowski, Natalia Szkaradek, Anna Wesołowska, Jacek Sapa, Grzegorz Kazek
Publikováno v:
Journal of Psychopharmacology. 34:1431-1442
Background: Our previous studies showed that xanthone derivatives with N-(2-methoxyphenyl)piperazine fragment have an affinity to the 5-HT1A receptor and show antidepressant-like properties in rodents. In this study, we tested three xanthone derivati
Autor:
Małgorzata Zygmunt, Marietta Ślusarczyk, Agnieszka Jankowska, Artur Świerczek, Adrian Bryła, Szczepan Mogilski, Grzegorz Kazek, Jacek Sapa, Elżbieta Wyska, Grażyna Chłoń-Rzepa
BackgroundTo verify the validity of the proposed pain treatment approach, which is based on concomitant blocking of the Transient Receptor Potential Ankyrin 1 (TRPA1) channel and phosphodiesterases (PDEs) 4B/7A activity, we continued our pharmacologi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de2c7fb7310db6c5b7ab4d7c41a3ab8f
https://ruj.uj.edu.pl/xmlui/handle/item/298315
https://ruj.uj.edu.pl/xmlui/handle/item/298315
Autor:
Jozef Mizera, Grzegorz Kazek, Bartosz Pomierny, Beata Bystrowska, Ewa Niedzielska-Andres, Lucyna Pomierny-Chamiolo
Publikováno v:
Molecular neurobiology. 59(9)
The problem of an unbalanced diet, overly rich in fats, affects a significant proportion of the population, including women of childbearing age. Negative metabolic and endocrine outcomes for offspring associated with maternal high-fat diet during pre