Insights into the Mechanism of Paraoxonase-1: Comparing the Reactivity of the Six-Bladed β-Propeller Hydrolases.

Autor: Grunkemeyer TJ; Department of Chemistry & Biochemistry and ‡Ohio State Biochemistry Program, The Ohio State University, Columbus, Ohio 43210, United States., Mata DG; Department of Chemistry & Biochemistry and ‡Ohio State Biochemistry Program, The Ohio State University, Columbus, Ohio 43210, United States., Doddapaneni K; Department of Chemistry & Biochemistry and ‡Ohio State Biochemistry Program, The Ohio State University, Columbus, Ohio 43210, United States., Murali S; Department of Chemistry & Biochemistry and ‡Ohio State Biochemistry Program, The Ohio State University, Columbus, Ohio 43210, United States., Magliery TJ; Department of Chemistry & Biochemistry and ‡Ohio State Biochemistry Program, The Ohio State University, Columbus, Ohio 43210, United States.

Publikováno v: Biochemistry [Biochemistry] 2024 Dec 17; Vol. 63 (24), pp. 3287-3299.

The antiviral enzyme viperin inhibits cholesterol biosynthesis.

Autor: Grunkemeyer TJ; Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA., Ghosh S; Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA., Patel AM; Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA., Sajja K; Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA., Windak J; Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA., Basrur V; Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA., Kim Y; Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA., Nesvizhskii AI; Department of Pathology, University of Michigan, Ann Arbor, Michigan, USA; Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, Michigan, USA., Kennedy RT; Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA., Marsh ENG; Department of Chemistry, University of Michigan, Ann Arbor, Michigan, USA; Department of Biological Chemisrty, University of Michigan, Ann Arbor, Michigan, USA. Electronic address: nmarsh@umich.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2021 Jul; Vol. 297 (1), pp. 100824. Date of Electronic Publication: 2021 May 23.

A hinge migration mechanism unlocks the evolution of green-to-red photoconversion in GFP-like proteins.

Autor: Kim H; Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287, USA., Zou T; Center for Biological Physics, Department of Physics, Arizona State University, Tempe, AZ 85287, USA., Modi C; Institute for Cellular and Molecular Biology, The University of Texas, Austin, TX 78712, USA., Dörner K; Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287, USA., Grunkemeyer TJ; Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287, USA., Chen L; Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287, USA., Fromme R; Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287, USA., Matz MV; Section of Integrative Biology, The University of Texas, Austin, TX 78712, USA., Ozkan SB; Center for Biological Physics, Department of Physics, Arizona State University, Tempe, AZ 85287, USA. Electronic address: banu.ozkan@asu.edu., Wachter RM; Department of Chemistry and Biochemistry, Arizona State University, Tempe, AZ 85287, USA; Center for Bioenergy and Photosynthesis, Arizona State University, Tempe, AZ 85287, USA. Electronic address: rwachter@asu.edu.

Publikováno v: Structure (London, England : 1993) [Structure] 2015 Jan 06; Vol. 23 (1), pp. 34-43.