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pro vyhledávání: '"Grune, Tilman (Prof. Dr.)"'
The Maillard reaction generates protein modifications which can accumulate during hyperglycemia or aging and may have inflammatory consequences. The proteasome is one of the major intracellular systems involved in the proteolytic degradation of modif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______266::9d122a353d7ba92be4d53b98c905e470
https://publishup.uni-potsdam.de/files/52757/pmnr1224.pdf
https://publishup.uni-potsdam.de/files/52757/pmnr1224.pdf
Autor:
Wiedmer, Petra (Dr.), Jung, Tobias, Castro, Jose Pedro, Pomatto, Laura C. D., Sun, Patrick Y., Davies, Kelvin J. A., Grune, Tilman (Prof. Dr.)
Sarcopenia represents a muscle-wasting syndrome characterized by progressive and generalized degenerative loss of skeletal muscle mass, quality, and strength occurring during normal aging. Sarcopenia patients are mainly suffering from the loss in mus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______266::4f922b3a11d19dcc073b9b45e31fea58
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/58249
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/58249
Autor:
Castro, Jose Pedro, Fernando, Raquel, Reeg, Sandra (Dr.), Meinl, Walter, Almeida, Henrique, Grune, Tilman (Prof. Dr.)
Aging is accompanied by the accumulation of oxidized proteins. To remove them, cells employ the proteasomal and autophagy-lysosomal systems; however, if the clearance rate is inferior to its formation, protein aggregates form as a hallmark of proteos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______266::1b58f2f6d14a16cdb213ec42804b8f35
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/50258
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/50258
Purpose of review In addition to the currently available lysosomotropic drugs and autophagy whole-body knockout mouse models, we provide alternative methods that enable the modulation and detection of autophagic flux in vivo, discussing advantages an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______266::c11d8b5f35b3b49e2f5488787fb06a50
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/48201
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/48201
Autor:
Stuetz, Wolfgang, Weber, Daniela (Dr.), Dollé, Martijn E. T., Jansen, Eugène, Grubeck-Loebenstein, Beatrix, Fiegl, Simone, Toussaint, Olivier, Bernhardt, Juergen, Gonos, Efstathios S., Franceschi, Claudio, Sikora, Ewa, Moreno-Villanueva, María, Breusing, Nicolle, Grune, Tilman (Prof. Dr.), Bürkle, Alexander
Blood micronutrient status may change with age. We analyzed plasma carotenoids, α-/γ-tocopherol, and retinol and their associations with age, demographic characteristics, and dietary habits (assessed by a short food frequency questionnaire) in a cr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______266::b1f17f7df0b6cd283ab4a4ddb6293079
https://publishup.uni-potsdam.de/files/40765/pmnr_449.online.pdf
https://publishup.uni-potsdam.de/files/40765/pmnr_449.online.pdf
Autor:
Castro, José Pedro, Wardelmann, Kristina (Dr.), Grune, Tilman (Prof. Dr. med.), Kleinridders, André (Prof. Dr.)
The brain orchestrates organ function and regulates whole body metabolism by the concerted action of neurons and glia cells in the central nervous system. To do so, the brain has tremendously high energy consumption and relies mainly on glucose utili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e49a9f65193df0f21dc86f6c0307d1ed
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/53025
https://publishup.uni-potsdam.de/frontdoor/index/index/docId/53025