Výsledky vyhledávání - "Grundman, Jennifer"

Understanding how genetic variation exerts its effects on the human brain in health and disease has been greatly informed by functional genomic characterization. Studies over the last decade have demonstrated robust evidence of convergent transcripti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38632a882e34d318d1d9fbecad4b85a1
https://doi.org/10.1101/2023.03.10.530869

Zobrazit plný text záznamu

Akademický článek

Tau isoforms drive differential transposable element and gene expression: Molecular and cell biology/tau.

Autor: Grundman, Jennifer Ann, Spencer, Brian, Rissman, Robert A.

Publikováno v: Alzheimer's & Dementia: The Journal of the Alzheimer's Association; Dec2020 Supplement S11, Vol. 16 Issue 11, p1-1, 1p

Zobrazit plný text záznamu

Single-cell genomics and regulatory networks for 388 human brains.

Autor: Emani PS; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Liu JJ; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Clarke D; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Jensen M; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Warrell J; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Gupta C; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, 53706, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, 53705, USA., Meng R; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Lee CY; Department of Computer Science, University of California, Irvine, CA, 92697, USA., Xu S; Department of Computer Science, University of California, Irvine, CA, 92697, USA., Dursun C; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Lou S; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Chen Y; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Chu Z; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA., Galeev T; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Hwang A; Department of Computer Science, University of California, Irvine, CA, 92697, USA.; Mathematical, Computational and Systems Biology, University of California, Irvine, CA, 92697, USA., Li Y; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA.; Department of Computer Science, Yale University, New Haven, CT, 06520, USA., Ni P; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Zhou X; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Bakken TE; Allen Institute for Brain Science, Seattle, WA, 98109, USA., Bendl J; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Bicks L; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA., Chatterjee T; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Cheng L; Tempus Labs, Inc., Chicago, IL, 60654, USA., Cheng Y; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA.; Department of Opthalmology, Perlman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA., Dai Y; Department of Computer Science, University of California, Irvine, CA, 92697, USA., Duan Z; Department of Computer Science, University of California, Irvine, CA, 92697, USA., Flaherty M; Tempus Labs, Inc., Chicago, IL, 60654, USA., Fullard JF; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Gancz M; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Garrido-Martín D; Department of Genetics, Microbiology and Statistics, Universitat de Barcelona, Barcelona, 08028, Spain., Gaynor-Gillett S; Tempus Labs, Inc., Chicago, IL, 60654, USA.; Department of Biology, Cornell College, Mount Vernon, IA, 52314, USA., Grundman J; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA., Hawken N; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA., Henry E; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Hoffman GE; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Mental Illness Research Education and Clinical Center, James J. Peters VA Medical Center, Bronx, NY, 10468, USA.; Center for Precision Medicine and Translational Therapeutics, James J. Peters VA Medical Center, Bronx, NY, 10468, USA., Huang A; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA., Jiang Y; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Jin T; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, 53706, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, 53705, USA., Jorstad NL; Allen Institute for Brain Science, Seattle, WA, 98109, USA., Kawaguchi R; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA.; Center for Autism Research and Treatment, Semel Institute, University of California, Los Angeles, CA, 90095, USA., Khullar S; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, 53706, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, 53705, USA., Liu J; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA., Liu J; Department of Computer Science, University of California, Irvine, CA, 92697, USA., Liu S; Waisman Center, University of Wisconsin-Madison, Madison, WI, 53705, USA., Ma S; Department of Neuroscience, Yale University, New Haven, CT, 06510, USA.; Institute of Neuroscience, CAS Center for Excellence in Brain Science and Intelligence Technology, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, 200031, China., Margolis M; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA., Mazariegos S; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA., Moore J; Department of Genomics and Computational Biology, UMass Chan Medical School, Worcester, MA, 01605, USA., Moran JR; Tempus Labs, Inc., Chicago, IL, 60654, USA., Nguyen E; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Phalke N; Department of Genomics and Computational Biology, UMass Chan Medical School, Worcester, MA, 01605, USA., Pjanic M; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Pratt H; Department of Genomics and Computational Biology, UMass Chan Medical School, Worcester, MA, 01605, USA., Quintero D; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA., Rajagopalan AS; Department of Computer Science, Yale University, New Haven, CT, 06520, USA., Riesenmy TR; Department of Statistics & Data Science, Yale University, New Haven, CT, 06520, USA., Shedd N; Department of Genomics and Computational Biology, UMass Chan Medical School, Worcester, MA, 01605, USA., Shi M; Tempus Labs, Inc., Chicago, IL, 60654, USA., Spector M; Tempus Labs, Inc., Chicago, IL, 60654, USA., Terwilliger R; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, 06520, USA., Travaglini KJ; Allen Institute for Brain Science, Seattle, WA, 98109, USA., Wamsley B; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA., Wang G; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Xia Y; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Xiao S; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA., Yang AC; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Zheng S; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA., Gandal MJ; Interdepartmental Program in Bioinformatics, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, 19104, USA.; Lifespan Brain Institute, The Children's Hospital of Philadelphia, Philadelphia, PA, 19104, USA., Lee D; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA., Lein ES; Allen Institute for Brain Science, Seattle, WA, 98109, USA.; Department of Neurological Surgery, University of Washington, Seattle, WA, 98195, USA.; Department of Laboratory Medicine and Pathology, University of Washington, Seattle, WA, 98195, USA., Roussos P; Center for Disease Neurogenomics, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.; Mental Illness Research Education and Clinical Center, James J. Peters VA Medical Center, Bronx, NY, 10468, USA.; Center for Precision Medicine and Translational Therapeutics, James J. Peters VA Medical Center, Bronx, NY, 10468, USA., Sestan N; Department of Neuroscience, Yale University, New Haven, CT, 06510, USA., Weng Z; Department of Genomics and Computational Biology, UMass Chan Medical School, Worcester, MA, 01605, USA., White KP; Yong Loo Lin School of Medicine, National University of Singapore, 117597, Singapore., Won H; Department of Genetics, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA., Girgenti MJ; Department of Psychiatry, Yale University School of Medicine, New Haven, CT, 06520, USA.; Wu Tsai Institute, Yale University, New Haven, CT, 06520, USA.; Clinical Neuroscience Division, National Center for Posttraumatic Stress Disorder, Veterans Affairs Connecticut Healthcare System, West Haven, CT, 06516, USA., Zhang J; Department of Computer Science, University of California, Irvine, CA, 92697, USA., Wang D; Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, 53706, USA.; Waisman Center, University of Wisconsin-Madison, Madison, WI, 53705, USA.; Department of Computer Sciences, University of Wisconsin-Madison, Madison, WI, 53706, USA., Geschwind D; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA.; Center for Autism Research and Treatment, Semel Institute, University of California, Los Angeles, CA, 90095, USA.; Department of Psychiatry, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, 90095, USA.; Institute for Precision Health, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, USA., Gerstein M; Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT, 06520, USA.; Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, 06520, USA.; Department of Computer Science, Yale University, New Haven, CT, 06520, USA.; Department of Statistics & Data Science, Yale University, New Haven, CT, 06520, USA.; Department of Biomedical Informatics & Data Science, Yale University, New Haven, CT, 06520, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Mar 30. Date of Electronic Publication: 2024 Mar 30.

Zobrazit plný text záznamu

Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies.

Autor: Nazeen S; Division of Movement Disorders, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Wang X; Division of Movement Disorders, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Zielinski D; Division of Movement Disorders, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Whitehead Institute of Biomedical Research, Cambridge, MA, USA., Lam I; Division of Movement Disorders, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Hallacli E; Division of Movement Disorders, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Xu P; Division of Movement Disorders, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Ethier E; Division of Movement Disorders, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Strom R; Division of Movement Disorders, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Zanella CA; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Nithianandam V; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Ritter D; The Center for Stem Cell Biology, Sloan-Kettering Institute for Cancer Research, New York, NY, USA., Henderson A; The Center for Stem Cell Biology, Sloan-Kettering Institute for Cancer Research, New York, NY, USA., Saurat N; The Center for Stem Cell Biology, Sloan-Kettering Institute for Cancer Research, New York, NY, USA., Afroz J; The Center for Stem Cell Biology, Sloan-Kettering Institute for Cancer Research, New York, NY, USA., Nutter-Upham A; Whitehead Institute of Biomedical Research, Cambridge, MA, USA., Benyamini H; Whitehead Institute of Biomedical Research, Cambridge, MA, USA., Copty J; Garvan Institute of Medical Research, Sydney, NSW, Australia., Ravishankar S; Garvan Institute of Medical Research, Sydney, NSW, Australia., Morrow A; Division of Movement Disorders, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA., Mitchel J; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Program in Health Sciences & Technology, Harvard Medical School & Massachusetts Institute of Technology, Boston, MA., Neavin D; Garvan Institute of Medical Research, Sydney, NSW, Australia., Gupta R; Garvan Institute of Medical Research, Sydney, NSW, Australia., Farbehi N; Garvan Institute of Medical Research, Sydney, NSW, Australia., Grundman J; Department of Human Genetics, University of California, Los Angeles, Los Angeles, CA, USA., Myers RH; Department of Neurology, Boston University School of Medicine, Boston, MA, USA., Scherzer CR; Division of Movement Disorders, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Trojanowski JQ; Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia, PA, USA., Van Deerlin VM; Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia, PA, USA., Cooper AA; Garvan Institute of Medical Research, Sydney, NSW, Australia., Lee EB; Center for Neurodegenerative Disease Research, University of Pennsylvania, Philadelphia, PA, USA., Erlich Y; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Lindquist S; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA., Peng J; Department of Computer Science, University of Illinois Urbana-Champaign, Champaign, IL, USA., Geschwind DH; Center for Autism Research and Treatment, Semel Institute, Program in Neurogenetics, Department of Neurology and Department of Human Genetics, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA., Powell J; Garvan Institute of Medical Research, Sydney, NSW, Australia.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Studer L; The Center for Stem Cell Biology, Sloan-Kettering Institute for Cancer Research, New York, NY, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Feany MB; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA., Sunyaev SR; Division of Genetics, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Khurana V; Division of Movement Disorders, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Harvard Stem Cell Institute, Cambridge, MA, USA.; Aligning Science Across Parkinson's (ASAP) Collaborative Research Network, Chevy Chase, MD, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Mar 07. Date of Electronic Publication: 2024 Mar 07.

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání