Data from Autoantibody Development under Treatment with Immune-Checkpoint Inhibitors

Autor: Diane van der Woude, René E.M. Toes, John B. Haanen, Tom W.J. Huizinga, Jaap A. Bakker, Annette Grummels, Els M.E. Verdegaal, Ellen H. Kapiteijn, Elisa A. Rozeman, Emma C. de Moel

Immune-checkpoint inhibitors (ICIs) activate the immune system to assault cancer cells in a manner that is not antigen specific. We hypothesized that tolerance may also be broken to autoantigens, resulting in autoantibody formation, which could be as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dfd65fb79cf617d2789e87015744582
https://doi.org/10.1158/2326-6066.c.6548081

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Anticentromere Antibody Levels and Isotypes and the Development of Systemic Sclerosis

Autor: Annette Grummels, Hans Scherer, Marie-Elise Truchetet, Jeska K de Vries-Bouwstra, Suzana Jordan, Karin Melsens, Tom W J Huizinga, Vanessa Smith, Nina M van Leeuwen, René E. M. Toes, Jaap A. Bakker, M. Boonstra, Anna-Maria Hoffmann-Vold, Sophie I E Liem, Oliver Distler

Publikováno v: Arthritis & rheumatology (Hoboken, N.J.), 73(12), 2338-2347. John Wiley and Sons Ltd
ARTHRITIS & RHEUMATOLOGY
Arthritis and Rheumatology, 2338-2347. WILEY
STARTPAGE=2338;ENDPAGE=2347;TITLE=Arthritis and Rheumatology

Objective: Little is known on the disease course of very early systemic sclerosis (SSc). Among the information yet to be elucidated is whether anticentromere antibody (ACA) isotype levels can serve as biomarkers for future SSc development and for org

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bace20848da31a10e038b77ac2b0af19
https://pubmed.ncbi.nlm.nih.gov/35536755

Presence of IgM anti-topoisomerase I antibodies is associated with disease progression in anti-topoisomerase I IgG positive systemic sclerosis

Autor: Boonstra, Maaike, Bakker, Jaap A, Grummels, Annette, Ninaber, Maarten K, Ajmone Marsan, Nina, Wortel, Corrie M, Huizinga, Tom W J, Jordan, Suzana, Hoffman-Vold, Anna-Maria, Distler, Oliver, Toes, René E M, Scherer, Hans Ulrich, de Vries-Bouwstra, Jeska K

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07cb8b0d515de5d25f398e553d03d535

Expansion of CMV-specific CD8+CD45RA+CD27- T cells in B-cell chronic lymphocytic leukemia

Autor: Mackus, WendelinaJ. M., Frakking, FlorineN.J., Grummels, Annette, Gamadia, LailaE., de Bree, GodelieveJ., Hamann, Dörte, van Lier, René A.W., van Oers, MarinusH.J. ^*

Publikováno v: In Blood 1 August 2003 102(3):1057-1063