Allicin inhibits SARS-CoV-2 replication and abrogates the antiviral host response in the Calu-3 proteome

Autor: Verena Nadin Fritsch, Haike Antelmann, Lorenz Adrian, Kirstin Mösbauer, Jörg Bernhardt, Gruhlke Mch, Daniela Niemeyer, Alan J. Slusarenko

The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) pandemic is a major health burden. Volatile garlic organosulfur compounds, such as the thiol-reactive allicin (diallyl thiosulfinate) exert strong antimicrobial activity against various

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f7ee3b437050eb152981a9fc0a773faf
https://doi.org/10.1101/2021.05.15.444275

Combating Black Fungus: Using Allicin as a Potent Antifungal Agent against Mucorales.

Autor: Schier C; Department of Plant Physiology, RWTH Aachen University, Worringer Weg 1, 52074 Aachen, Germany.; Institute of Immunology, RWTH Aachen University Hospital, Pauwelsstraße 30, 52074 Aachen, Germany., Gruhlke MCH; GENAWIF e.V.-Society for Natural Compound and Active Ingredient Research, Lukasstraße 1, 52070 Aachen, Germany.; Institute of Applied Microbiology-iAMB, Aachener Biology and Biotechnology-ABBt, RWTH Aachen University, 52074 Aachen, Germany., Reucher G; Institute of Immunology, RWTH Aachen University Hospital, Pauwelsstraße 30, 52074 Aachen, Germany., Slusarenko AJ; Department of Plant Physiology, RWTH Aachen University, Worringer Weg 1, 52074 Aachen, Germany.; GENAWIF e.V.-Society for Natural Compound and Active Ingredient Research, Lukasstraße 1, 52070 Aachen, Germany., Rink L; Institute of Immunology, RWTH Aachen University Hospital, Pauwelsstraße 30, 52074 Aachen, Germany.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 15; Vol. 24 (24). Date of Electronic Publication: 2023 Dec 15.

Allicin as a Volatile or Nebulisable Antimycotic for the Treatment of Pulmonary Mycoses: In Vitro Studies Using a Lung Flow Test Rig.

Autor: Schier C; Department of Plant Physiology, RWTH Aachen University, 52074 Aachen, Germany., Foerster Née Reiter J; GENAWIF e.V.-Society for Natural Compound and Active Ingredient Research, 52070 Aachen, Germany., Heupel M; Landwirtschaftskammer Rheinland, 50765 Köln-Auweiler, Germany., Dörner P; Chair of Fluid Mechanics and Institute of Aerodynamics, RWTH Aachen University, 52062 Aachen, Germany., Klaas M; Chair of Fluid Mechanics and Institute of Aerodynamics, RWTH Aachen University, 52062 Aachen, Germany., Schröder W; Chair of Fluid Mechanics and Institute of Aerodynamics, RWTH Aachen University, 52062 Aachen, Germany., Rink L; Institute of Immunology, RWTH Aachen University Hospital, 52074 Aachen, Germany., Slusarenko AJ; Department of Plant Physiology, RWTH Aachen University, 52074 Aachen, Germany.; GENAWIF e.V.-Society for Natural Compound and Active Ingredient Research, 52070 Aachen, Germany., Gruhlke MCH; Department of Plant Physiology, RWTH Aachen University, 52074 Aachen, Germany.; GENAWIF e.V.-Society for Natural Compound and Active Ingredient Research, 52070 Aachen, Germany.; Institute of Applied Microbiology-iAMB, Aachener Biology and Biotechnology-ABBt, RWTH Aachen University, 52074 Aachen, Germany.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2022 Jun 14; Vol. 23 (12). Date of Electronic Publication: 2022 Jun 14.

The Effect of Allicin on the Proteome of SARS-CoV-2 Infected Calu-3 Cells.

Autor: Mösbauer K; Institute of Virology, Berlin Institute of Health, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Berlin, Germany.; German Centre for Infection Research (DZIF), Berlin, Germany., Fritsch VN; Institute for Biology-Microbiology, Freie Universität Berlin, Berlin, Germany., Adrian L; Department Environmental Biotechnology, Helmholtz Centre for Environmental Research-UFZ, Leipzig, Germany.; Fachgebiet Geobiotechnologie, Technische Universität Berlin, Berlin, Germany., Bernhardt J; Institute for Microbiology, University of Greifswald, Greifswald, Germany., Gruhlke MCH; Department of Plant Physiology, RWTH Aachen University, Aachen, Germany., Slusarenko AJ; Department of Plant Physiology, RWTH Aachen University, Aachen, Germany., Niemeyer D; Institute of Virology, Berlin Institute of Health, Charité-Universitätsmedizin Berlin, Freie Universität Berlin, Berlin, Germany.; German Centre for Infection Research (DZIF), Berlin, Germany., Antelmann H; Institute for Biology-Microbiology, Freie Universität Berlin, Berlin, Germany.

Publikováno v: Frontiers in microbiology [Front Microbiol] 2021 Oct 28; Vol. 12, pp. 746795. Date of Electronic Publication: 2021 Oct 28 (Print Publication: 2021).

Allicin, the Odor of Freshly Crushed Garlic: A Review of Recent Progress in Understanding Allicin's Effects on Cells.

Autor: Borlinghaus J; Department of Plant Physiology, RWTH Aachen University, 52056 Aachen, Germany., Foerster Née Reiter J; Department of Plant Physiology, RWTH Aachen University, 52056 Aachen, Germany., Kappler U; School of Chemistry and Molecular Biosciences, University of Queensland, St. Lucia, Qld 4072, Australia., Antelmann H; Institute of Biology-Microbiology, Freie Universität Berlin, 14195 Berlin, Germany., Noll U; Department of Plant Physiology, RWTH Aachen University, 52056 Aachen, Germany., Gruhlke MCH; Department of Plant Physiology, RWTH Aachen University, 52056 Aachen, Germany., Slusarenko AJ; Department of Plant Physiology, RWTH Aachen University, 52056 Aachen, Germany.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2021 Mar 10; Vol. 26 (6). Date of Electronic Publication: 2021 Mar 10.